VINBLASTINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C46H58N4O9
Molecular Weight	810.9741
Optical Activity	UNSPECIFIED
Defined Stereocenters	9 / 9
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of VINBLASTINE

Structure Search

SMILES

[H][C@@]12N3CC[C@@]14C5=CC(=C(OC)C=C5N(C)[C@@]4([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC)[C@]6(C[C@@]7([H])CN(C[C@](O)(CC)C7)CCC8=C6NC9=C8C=CC=C9)C(=O)OC

InChI

InChIKey=JXLYSJRDGCGARV-CFWMRBGOSA-N

InChI=1S/C46H58N4O9/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3/t28-,37-,38+,39+,42-,43+,44+,45-,46-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C46H58N4O9
Molecular Weight	810.9741
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	8 / 9
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:11:22 UTC 2023` Edited by `admin` on `Fri Dec 15 15:11:22 UTC 2023`
Record UNII	5V9KLZ54CY
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VINBLASTINE

Official Name

English

VINBLASTINE [VANDF]

Common Name

English

vinblastine [INN]

Common Name

English

VINCRISTINE SULFATE IMPURITY H [EP IMPURITY]

Common Name

English

Vinblastine [WHO-DD]

Common Name

English

VINBLASTINA

Brand Name

English

NSC-47842

Code

English

VINBLASTINE [HSDB]

Common Name

English

VINDESINE SULFATE IMPURITY B [EP IMPURITY]

Common Name

English

VINBLASTINE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C932

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

WHO-VATC

QL01CA01

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

LIVERTOX

1029

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

NDF-RT

N0000007780

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

NDF-RT

N0000007780

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

NDF-RT

N0000175612

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

8.2

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

WHO-ATC

L01CA01

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

EPA PESTICIDE CODE

600072

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

NCI_THESAURUS

C67422

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

Code System Code Type Description

ChEMBL

CHEMBL159

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

FDA UNII

5V9KLZ54CY

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

DRUG CENTRAL

2823

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

DRUG BANK

DB00570

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

PUBCHEM

13342

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

DAILYMED

5V9KLZ54CY

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

HSDB

3263

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

MESH

D014747

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

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CHEBI

27375

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

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MERCK INDEX

m11449

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

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Merck Index

ECHA (EC/EINECS)

212-734-0

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

LACTMED

Vinblastine

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

EVMPD

SUB00052MIG

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

NSC

47842

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

IUPHAR

6851

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

NCI_THESAURUS

C930

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

SMS_ID

100000079086

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

CAS

865-21-4

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

RXCUI

11198

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

RxNorm

WIKIPEDIA

VINBLASTINE

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

EPA CompTox

DTXSID8021430

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

INN

1101

Created by admin on Fri Dec 15 15:11:23 UTC 2023 , Edited by admin on Fri Dec 15 15:11:23 UTC 2023

PRIMARY

Related Record Type Details


					Y49M64GZ4Q

MRP-1

TRANSPORTER -> SUBSTRATE

Amount:


					N00W22YO2B

VINBLASTINE SULFATE

SALT/SOLVATE -> PARENT


					WCI46BYD7T

BSEP

TRANSPORTER -> SUBSTRATE


					GL0S96GM0A

MDR-3

TRANSPORTER -> SUBSTRATE

Related Record Type Details


					PN45E4NV2N

Vinblastine N-Oxide

PRODRUG -> METABOLITE ACTIVE

Amount:

Related Record Type Details


					T5IRO3534A

VINCRISTINE SULFATE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					CPH2U7DNDY

VINDESINE SULFATE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					5V9KLZ54CY

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Route of Elimination	PHARMACOKINETIC

Route of Elimination	PHARMACOKINETIC