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Details

Stereochemistry ABSOLUTE
Molecular Formula C37H67NO13
Molecular Weight 733.9268
Optical Activity UNSPECIFIED
Defined Stereocenters 18 / 18
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Erythromycin

SMILES

[H][C@@]1(C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)O[C@H]2[C@H](C)[C@@H](O[C@]3([H])O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]2C

InChI

InChIKey=ULGZDMOVFRHVEP-RWJQBGPGSA-N
InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1

HIDE SMILES / InChI
Molecular Formula C37H67NO13
Molecular Weight 733.9268
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 18 / 18
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:10:08 UTC 2023
Edited
by admin
on Sat Dec 16 17:10:08 UTC 2023
Record UNII
63937KV33D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Erythromycin
EP   GREEN BOOK   HSDB   INN   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
INN  
Official Name English
ERYTHROMYCIN [MART.]
Common Name English
Erythromycin [WHO-DD]
Common Name English
TORLAMICINA
Common Name English
ROBIMYCIN
Brand Name English
A/T/S
Brand Name English
ERYTHROMYCINUM [WHO-IP LATIN]
Common Name English
ERYTHROMYCIN [ORANGE BOOK]
Common Name English
ERYGEL
Brand Name English
E-SOLVE 2
Brand Name English
ERYTHROMYCIN [HSDB]
Common Name English
ERYCETTE
Brand Name English
ERYTHROMYCIN COMPONENT OF BENZAMYCIN
Common Name English
E-GLADES
Brand Name English
NSC-55929
Code English
ERYTHRA-DERM
Brand Name English
ERYTHROMYCIN-A
Common Name English
E-BASE
Brand Name English
ERYTHROMYCIN A
Common Name English
ERYTHROMYCIN [EP MONOGRAPH]
Common Name English
PCE (ERYTHROMYCIN)
Brand Name English
ERYTHRO-STATIN
Brand Name English
ERYTHROMYCIN ESTOLATE IMPURITY, FREE ERYTHROMYCIN- [USP IMPURITY]
Common Name English
ERY-TAB
Brand Name English
PANTOMICINA
Common Name English
ERYTHROMYCIN [WHO-IP]
Common Name English
R-P MYCIN
Brand Name English
ILOTYCIN
Brand Name English
ERYTHROMYCIN [GREEN BOOK]
Common Name English
ERYTHROMYCIN ESTOLATE IMPURITY, FREE ERYTHROMYCIN [EP IMPURITY]
Common Name English
erythromycin [INN]
Common Name English
T-STAT
Brand Name English
STATICIN
Brand Name English
J01FA01
Code English
ERYDERM
Brand Name English
SANSAC
Brand Name English
ERYTHROMYCIN [JAN]
Common Name English
EMGEL
Brand Name English
AKNE-MYCIN
Brand Name English
BENZAMYCIN COMPONENT ERYTHROMYCIN
Common Name English
ERYTHROMYCIN [VANDF]
Common Name English
ERYMAX
Brand Name English
ERYTHROMYCIN [MI]
Common Name English
ERYTHROMYCIN [USP MONOGRAPH]
Common Name English
E-MYCIN
Brand Name English
ERYC
Brand Name English
ERYTHROMYCIN [USP-RS]
Common Name English
C-SOLVE-2
Brand Name English
Classification Tree Code System Code
NDF-RT N0000007529
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
WHO-ATC S01AA17
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
WHO-ATC D10AF52
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
LIVERTOX NBK547881
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
WHO-ATC D10AF02
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
NDF-RT N0000175877
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
WHO-VATC QJ51RF02
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 6.2.2
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
CFR 21 CFR 520.823
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
WHO-VATC QD10AF02
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
WHO-VATC QS01AA17
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
NDF-RT N0000007529
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
NDF-RT N0000009982
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
NCI_THESAURUS C261
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
WHO-VATC QJ01FA01
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
WHO-VATC QJ51FA01
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
NDF-RT N0000175935
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
WHO-ATC J01FA01
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
CFR 21 CFR 522.820
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
CFR 21 CFR 526.820
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
CFR 21 CFR 556.230
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
CFR 21 CFR 558.248
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
NDF-RT N0000007529
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
Code System Code Type Description
ChEMBL
CHEMBL2110577
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
ChEMBL
CHEMBL532
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
PUBCHEM
12560
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
NSC
55929
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
LACTMED
Erythromycin
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
IUPHAR
1456
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
SMS_ID
100000092382
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
EVMPD
SUB06605MIG
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
RS_ITEM_NUM
1242000
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
HSDB
3074
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
FDA UNII
63937KV33D
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
DRUG CENTRAL
1048
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
DAILYMED
63937KV33D
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
CHEBI
64268
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
INN
39
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
DRUG BANK
DB00199
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
RXCUI
4053
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY RxNorm
WHO INTERNATIONAL PHARMACOPEIA
ERYTHROMYCIN
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY Description: White or slightly yellow crystals or powder; odourless or almost odourless.Solubility: Soluble in 1000 parts of water but less soluble in hot water; freely soluble in ethanol (~750 g/l) TS and ether R.Category: Antibacterial drug.Storage: Erythromycin should be kept in a tightly closed container, protected from light.Additional information: Erythromycin is slightly hygroscopic.Definition: Erythromycin is a mixture of substances produced by the growth of certain strains of Streptomyces erythreus. The main component of the mixture is erythromycin A with lesser amounts of erythromycins B and C.
EPA CompTox
DTXSID4022991
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
WIKIPEDIA
ERYTHROMYCIN
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
MERCK INDEX
m5009
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY Merck Index
NCI_THESAURUS
C476
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
CAS
114-07-8
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
CHEBI
42355
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
MESH
D004917
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
ECHA (EC/EINECS)
204-040-1
Created by admin on Sat Dec 16 17:10:13 UTC 2023 , Edited by admin on Sat Dec 16 17:10:13 UTC 2023
PRIMARY
Related Record Type Details
Structure of ERYTHROMYCIN MONOHYDRATE
SOLVATE->ANHYDROUS
Structure of ERYTHROMYCIN DIHYDRATE
SOLVATE->ANHYDROUS
MULTIDRUG RESISTANCE PROTEIN 1
TRANSPORTER -> INHIBITOR
MULTIDRUG RESISTANCE PROTEIN 1
TRANSPORTER -> SUBSTRATE
CYTOCHROME P450 3A4
METABOLIC ENZYME -> SUBSTRATE
CYTOCHROME P450 3A5
METABOLIC ENZYME -> SUBSTRATE
Structure of ERYTHROMYCIN HYDRIODIDE MONOHYDRATE
SALT/SOLVATE -> PARENT
Structure of ERYTHROMYCIN OXALATE DIHYDRATE
SALT/SOLVATE -> PARENT
CYTOCHROME P450 3A12 (CANINE)
METABOLIC ENZYME -> SUBSTRATE
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Structure of ERYTHROMYCIN C-13
LABELED -> NON-LABELED
Structure of ERYTHROMYCIN ESTOLATE
SUBSTANCE->BASIS OF STRENGTH
ALDEHYDE OXIDASE
METABOLIC ENZYME -> INHIBITOR
IC50
Structure of ERYTHROMYCIN N-METHYL C-14
LABELED -> NON-LABELED
CYTOCHROME P450 1A2 (CANINE)
METABOLIC ENZYME -> SUBSTRATE
Related Record Type Details
Structure of PSEUDOERYTHROMYCIN A ENOL ETHER
IMPURITY -> PARENT
Structure of ERYTHROMYCIN A N-OXIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of ERYTHROMYCIN F
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of PSEUDOERYTHROMYCIN A HEMIKETAL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of ERYTHROMYCIN D
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of Erythromycin
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC POPULATION: ADULTS

MIC BIOLOGICAL SUSCEPTIBILITY: S. PNEUMONIAE, S. PYOGENES

MIC BIOLOGICAL SUSCEPTIBILITY: S. PNEUMONIAE, S. PYOGENES

Tmax PHARMACOKINETIC COMBINATION FORM: ERYTHROMYCIN ETHYLSUCCINATE

FOOD EFFECT: DELAYED Tmax

Biological Half-life PHARMACOKINETIC POPULATION: END-STAGE RENAL DISEASE

Volume of Distribution PHARMACOKINETIC
MIC BIOLOGICAL SUSCEPTIBILITY: S. AUREUS

MIC BIOLOGICAL SUSCEPTIBILITY: S. AUREUS

Tmax PHARMACOKINETIC FOOD EFFECT: DELAYED Tmax

COMBINATION FORM: ERYTHROMYCIN STEARATE

Tmax PHARMACOKINETIC FOOD EFFECT: BASE

COMBINATION FORM: ERYTHROMYCIN BASE

MIC BIOLOGICAL SUSCEPTIBILITY: S. PNEUMONIAE, S. PYOGENES

Biological Half-life PHARMACOKINETIC POPULATION: NEONATES (LESS THAN OR EQUAL TO 15 DAYS OF AGE)

MIC BIOLOGICAL SUSCEPTIBILITY: S. AUREUS

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