Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C23H17FN6O2 |
| Molecular Weight | 428.4185 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CN(N=C(C2=CC=NN2C3=CC=CC=C3)C1=O)C4=CC=C(C=C4F)N5C=CC=N5
InChI
InChIKey=KVHRYLNQDWXAGI-UHFFFAOYSA-N
InChI=1S/C23H17FN6O2/c1-32-21-15-29(19-9-8-17(14-18(19)24)28-13-5-11-25-28)27-22(23(21)31)20-10-12-26-30(20)16-6-3-2-4-7-16/h2-15H,1H3
| Molecular Formula | C23H17FN6O2 |
| Molecular Weight | 428.4185 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:39:56 UTC 2023
by
admin
on
Sat Dec 16 08:39:56 UTC 2023
|
| Record UNII |
6650W303H0
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
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Official Name | English | ||
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Systematic Name | English | ||
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Code | English | ||
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Common Name | English | ||
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Systematic Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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FDA ORPHAN DRUG |
689219
Created by
admin on Sat Dec 16 08:39:56 UTC 2023 , Edited by admin on Sat Dec 16 08:39:56 UTC 2023
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EU-Orphan Drug |
EU/3/19/2154
Created by
admin on Sat Dec 16 08:39:56 UTC 2023 , Edited by admin on Sat Dec 16 08:39:56 UTC 2023
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|
FDA ORPHAN DRUG |
689319
Created by
admin on Sat Dec 16 08:39:56 UTC 2023 , Edited by admin on Sat Dec 16 08:39:56 UTC 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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EF-96
Created by
admin on Sat Dec 16 08:39:56 UTC 2023 , Edited by admin on Sat Dec 16 08:39:56 UTC 2023
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PRIMARY | |||
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1238697-26-1
Created by
admin on Sat Dec 16 08:39:56 UTC 2023 , Edited by admin on Sat Dec 16 08:39:56 UTC 2023
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PRIMARY | |||
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46848915
Created by
admin on Sat Dec 16 08:39:56 UTC 2023 , Edited by admin on Sat Dec 16 08:39:56 UTC 2023
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PRIMARY | |||
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6650W303H0
Created by
admin on Sat Dec 16 08:39:56 UTC 2023 , Edited by admin on Sat Dec 16 08:39:56 UTC 2023
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PRIMARY | |||
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C166905
Created by
admin on Sat Dec 16 08:39:56 UTC 2023 , Edited by admin on Sat Dec 16 08:39:56 UTC 2023
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PRIMARY | |||
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DB14774
Created by
admin on Sat Dec 16 08:39:56 UTC 2023 , Edited by admin on Sat Dec 16 08:39:56 UTC 2023
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PRIMARY | |||
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100000178413
Created by
admin on Sat Dec 16 08:39:56 UTC 2023 , Edited by admin on Sat Dec 16 08:39:56 UTC 2023
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PRIMARY | |||
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10456
Created by
admin on Sat Dec 16 08:39:56 UTC 2023 , Edited by admin on Sat Dec 16 08:39:56 UTC 2023
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PRIMARY |
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Its selectivity over other PDEs could be up to 15 000-fold. Its pharmacokinetics were promising, including high brain penetration in mice
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