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Details

Stereochemistry ABSOLUTE
Molecular Formula C27H36N2O4
Molecular Weight 452.5857
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of REPAGLINIDE

SMILES

CCOC1=C(C=CC(CC(=O)N[C@@H](CC(C)C)C2=C(C=CC=C2)N3CCCCC3)=C1)C(O)=O

InChI

InChIKey=FAEKWTJYAYMJKF-QHCPKHFHSA-N
InChI=1S/C27H36N2O4/c1-4-33-25-17-20(12-13-22(25)27(31)32)18-26(30)28-23(16-19(2)3)21-10-6-7-11-24(21)29-14-8-5-9-15-29/h6-7,10-13,17,19,23H,4-5,8-9,14-16,18H2,1-3H3,(H,28,30)(H,31,32)/t23-/m0/s1

HIDE SMILES / InChI
Molecular Formula C27H36N2O4
Molecular Weight 452.5857
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:52:42 UTC 2023
Edited
by admin
on Fri Dec 15 15:52:42 UTC 2023
Record UNII
668Z8C33LU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
REPAGLINIDE
EMA EPAR   EP   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
USAN   INN  
Official Name English
REPAGLINIDE [EP MONOGRAPH]
Common Name English
NSC-759893
Code English
PRANDIN
Brand Name English
REPAGLINIDE [MART.]
Common Name English
REPAGLINIDE [VANDF]
Common Name English
Repaglinide [WHO-DD]
Common Name English
A10BX02
Code English
REPAGLINIDE [USAN]
Common Name English
AGEE-623ZW
Code English
REPAGLINIDE [USP-RS]
Common Name English
REPAGLINIDE [ORANGE BOOK]
Common Name English
REPAGLINIDE [JAN]
Common Name English
REPAGLINIDE [MI]
Common Name English
(+)-2-ETHOXY-.ALPHA.-(((S)-.ALPHA.-ISOBUTYL-O-PIPERIDINOBENZYL)CARBAMOYL)-P-TOLUIC ACID
Common Name English
REPAGLINIDE [USP MONOGRAPH]
Common Name English
AG-EE 623 ZW
Code English
AG-EE-623-ZW
Code English
AG-EE-623ZW
Code English
REPAGLINIDE [EMA EPAR]
Common Name English
repaglinide [INN]
Common Name English
(S)-2-ETHOXY-4-(2-(METHYL-1-(2-(1-PIPERIDINYL)PHENYL)BUTYLAMINO)-2-OXOETHYL)-BENZOIC ACID
Systematic Name English
Classification Tree Code System Code
WHO-VATC QA10BD14
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
WHO-ATC A10BD14
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
NDF-RT N0000175448
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
WHO-VATC QA10BX02
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
WHO-ATC A10BX02
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
LIVERTOX NBK548879
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
NDF-RT N0000175428
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
NCI_THESAURUS C98079
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
Code System Code Type Description
PUBCHEM
65981
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
ChEMBL
CHEMBL1272
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
INN
6818
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
DRUG CENTRAL
2366
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
WIKIPEDIA
REPAGLINIDE
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
LACTMED
Repaglinide
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
RS_ITEM_NUM
1600813
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
DAILYMED
668Z8C33LU
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
SMS_ID
100000091273
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
NSC
759893
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
EVMPD
SUB10280MIG
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
RXCUI
73044
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY RxNorm
FDA UNII
668Z8C33LU
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
IUPHAR
6841
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
DRUG BANK
DB00912
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
EPA CompTox
DTXSID3023552
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
CAS
135062-02-1
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
USAN
KK-76
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
NCI_THESAURUS
C47703
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
MERCK INDEX
m9526
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY Merck Index
MESH
C072379
Created by admin on Fri Dec 15 15:52:42 UTC 2023 , Edited by admin on Fri Dec 15 15:52:42 UTC 2023
PRIMARY
Related Record Type Details
Structure of REPAGLINIDE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
EP
OATP-8
TRANSPORTER -> INHIBITOR
CYTOCHROME P450 2C8
METABOLIC ENZYME -> SUBSTRATE
OATP-B
TRANSPORTER -> INHIBITOR
OCT-1
TRANSPORTER -> INHIBITOR
Structure of REPAGLINIDE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
OATP1B1
TRANSPORTER -> INHIBITOR
ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8
TARGET -> INHIBITOR
Related Record Type Details
Structure of 2-DESPIPERIDYL-2-AMINO REPAGLINIDE
METABOLITE -> PARENT
CYP2C8 and 3A4 in vitro
FECAL; PLASMA; URINE
Structure of 2-DESPIPERIDINYL-2-(4-CARBOXYBUTYL)AMINO)REPAGLINIDE
METABOLITE INACTIVE -> PARENT
CYP2C8 and 3A4 in vitro
MAJOR
FECAL
Structure of REPAGLINIDE ACYL-.BETA.-D-GLUCURONIDE
METABOLITE -> PARENT
PLASMA; URINE
Related Record Type Details
Structure of REPAGLINIDE, (-)-
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of REPAGLINIDE, (-)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of REPAGLINIDE ETHYL ESTER
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 3-ETHOXY-4-ETHOXYCARBONYLPHENYLACETIC ACID
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of REPAGLINIDE ETHYL ESTER
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 2-DESISOPROPYL-2-PHENYL REPAGLINIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 4-(CARBOXYMETHYL)-2-ETHOXYBENZOIC ACID
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 3-ETHOXY-4-ETHOXYCARBONYLPHENYLACETIC ACID
IMPURITY -> PARENT
correction factors: for the calculation of contents, multiply the peak areas of the following impurity by the corresponding correction factor: impurity B = 0.7
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 4-(CARBOXYMETHYL)-2-ETHOXYBENZOIC ACID
IMPURITY -> PARENT
correction factors: for the calculation of contents, multiply the peak areas of the following impurity by the corresponding correction factor: impurity A = 0.6
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-METHYL-1-(2-PIPERIDINOPHENYL)-1-BUTYLAMINE, (S)-
IMPURITY -> PARENT
correction factors: for the calculation of contents, multiply the peak areas of the following impurity by the corresponding correction factor: impurity C = 3.1
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of REPAGLINIDE
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