CHLORAMPHENICOL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C11H12Cl2N2O5
Molecular Weight	323.129
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CHLORAMPHENICOL

Structure Search

SMILES

OC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)C1=CC=C(C=C1)[N+]([O-])=O

InChI

InChIKey=WIIZWVCIJKGZOK-RKDXNWHRSA-N

InChI=1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)/t8-,9-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C11H12Cl2N2O5
Molecular Weight	323.129
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:00:29 UTC 2023` Edited by `admin` on `Fri Dec 15 15:00:29 UTC 2023`
Record UNII	66974FR9Q1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CHLORAMPHENICOL

Official Name

English

CHLORAMPHENICOL [MI]

Common Name

English

CHLOROPTIC-P S.O.P. COMPONENT CHLORAMPHENICOL

Common Name

English

NSC-3069

Code

English

OPHTHOCHLOR

Brand Name

English

CHLOROMYCETIN

Brand Name

English

CHLORAMPHENICOL [MART.]

Common Name

English

CHLORAMPHENICOL [HSDB]

Common Name

English

MYCHEL

Brand Name

English

Chloramphenicol [WHO-DD]

Common Name

English

CHLORAMPHENICOL COMPONENT OF CHLOROMYXIN

Common Name

English

CHLOROPTIC

Brand Name

English

CHLORAMPHENICOL [USP-RS]

Common Name

English

CHLORAMPHENICOLUM

Common Name

English

D-THREO-(-)-2,2-DICHLORO-N-(.BETA.-HYDROXY-.ALPHA.-(HYDROXYMETHYL)-P-NITROPHENETHYL)ACETAMIDE

Common Name

English

CHLORAMPHENICOL [GREEN BOOK]

Common Name

English

CHLORAMPHENICOL [WHO-IP]

Common Name

English

2,2-DICHLORO-N-((1R,2R)-2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL)ACETAMIDE

Systematic Name

English

OPHTHOCORT COMPONENT CHLORAMPHENICOL

Common Name

English

chloramphenicol [INN]

Common Name

English

CHLORAMPHENICOL [ORANGE BOOK]

Common Name

English

CHLORAMPHENICOL COMPONENT OF CHLOROMYCETIN HYDROCORTISONE

Common Name

English

CHLORAMPHENICOL COMPONENT OF CHLOROPTIC-P S.O.P.

Common Name

English

OPTOMYCIN

Brand Name

English

NOVOMYCETIN

Common Name

English

CHLORAMPHENICOL [VANDF]

Common Name

English

CHLOROMYCETIN HYDROCORTISONE COMPONENT CHLORAMPHENICOL

Common Name

English

ELASE-CHLOROMYCETIN COMPONENT CHLORAMPHENICOL

Common Name

English

CHLORAMPHENICOL [USP MONOGRAPH]

Common Name

English

CHLORAMPHENICOL [JAN]

Common Name

English

CHLORAMPHENICOL COMPONENT OF ELASE-CHLOROMYCETIN

Common Name

English

CHLORAMPHENICOLUM [HPUS]

Common Name

English

SYNTHOMYCETIN

Common Name

English

CHLORAMPHENICOL [IARC]

Common Name

English

CHLORAMPHENICOLUM [WHO-IP LATIN]

Common Name

English

CHLORAMPHENICOL [EP MONOGRAPH]

Common Name

English

AMPHICOL

Brand Name

English

CHLORAMPHENICOL COMPONENT OF OPHTHOCORT

Common Name

English

CHLOROMYXIN COMPONENT CHLORAMPHENICOL

Common Name

English

ECONOCHLOR

Brand Name

English

ACETAMIDE, 2,2-DICHLORO-N-(2-HYDROXY-1-(HYDROXYMETHYL)-2-(4-NITROPHENYL)ETHYL)-, (R-(R*,R*))-

Common Name

English

CHLOROFAIR

Brand Name

English

Classification Tree Code System Code

WHO-VATC

QD10AF03

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

NCI_THESAURUS

C258

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-ATC

G01AA05

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-ATC

S03AA08

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-VATC

QD06AX02

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-VATC

QG01AA55

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-VATC

QJ01BA01

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

CFR

21 CFR 524.390

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

CFR

21 CFR 530.41

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-VATC

QS03AA08

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-ATC

D10AF03

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-ATC

D06AX02

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

CFR

21 CFR 520.390

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

IARC

Chloramphenicol

WHO-VATC

QJ51BA01

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-VATC

QJ51RB01

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-VATC

QS02AA01

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

NDF-RT

N0000175479

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

NDF-RT

N0000175479

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

CFR

21 CFR 522.390

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-ATC

J01BA01

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

NDF-RT

N0000175480

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.2.2

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-VATC

QG01AA05

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-ATC

S01AA01

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

CFR

21 CFR 520.390A

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

LIVERTOX

NBK548105

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-ATC

S02AA01

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

WHO-VATC

QS01AA01

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

CFR

21 CFR 520.390B

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

Code System Code Type Description

MESH

D002701

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

CAS

56-75-7

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

INN

977

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

NCI_THESAURUS

C363

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

EPA CompTox

DTXSID7020265

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

HSDB

3027

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

ECHA (EC/EINECS)

200-287-4

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

PUBCHEM

5959

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

DRUG BANK

DB00446

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

MERCK INDEX

m3347

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

Merck Index

ChEMBL

CHEMBL130

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

DAILYMED

66974FR9Q1

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

NSC

3069

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

ALANWOOD

chloramphenicol

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

LACTMED

Chloramphenicol

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

FDA UNII

66974FR9Q1

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

DRUG CENTRAL

589

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

CHEBI

17698

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

EVMPD

SUB06173MIG

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

SMS_ID

100000092772

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

WIKIPEDIA

CHLORAMPHENICOL

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

RS_ITEM_NUM

1107004

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

RXCUI

2348

Created by admin on Fri Dec 15 15:00:29 UTC 2023 , Edited by admin on Fri Dec 15 15:00:29 UTC 2023

PRIMARY

RxNorm

Related Record Type Details


					0M77ZW789J

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B7

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MAJOR


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> INHIBITOR

Interaction Type:

COMPETITIVE INHIBITOR

Qualification:

Ki

Amount:


					3318TFY23Q

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A9

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MINOR


					FGQ0BCJ2G9

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A6

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MINOR


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME->WEAK INHIBITOR

Interaction Type:

COMPETITIVE INHIBITOR

Qualification:

Ki

Amount:


					65P5WPF3BJ

METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS

TARGET ORGANISM->INHIBITOR

Amount:


					L9DP834D1P

CYTOCHROME P450 2C9

METABOLIC ENZYME -> NON-INHIBITOR


					L0423Z5LDW

CYTOCHROME P450 2C8

METABOLIC ENZYME -> NON-INHIBITOR


					FMO6OC31WV

CHLORAMPHENICOL MONOETHANOLAMINE SUCCINATE

SALT/SOLVATE -> PARENT


					03BYF220B6

CYTOCHROME P450 2E1

METABOLIC ENZYME -> NON-INHIBITOR

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					081I12ZA58

CYTOCHROME P450 2C19

METABOLIC ENZYME -> INHIBITOR

Comments:

MIXED INHIBITION

Interaction Type:

MAJOR

Qualification:

Ki

Amount:

Related Record Type Details


					Z42JE4RY2X

CHLORAMPHENICOL 1-O-GLUCURONIDE

METABOLITE -> PARENT

Interaction Type:

MINOR


					5N9C7NNS4Q

CHLORAMPHENICOL 3-GLUCORONIDE

METABOLITE -> PARENT

Interaction Type:

MAJOR

Related Record Type Details


					8FB0B566G6

2-AMINO-1-(4-NITROPHENYL)-1,3-PROPANEDIOL

IMPURITY -> PARENT


					NX859P8MB0

4-NITROBENZALDEHYDE

IMPURITY -> PARENT

Amount:

Related Record Type Details


					66974FR9Q1

CHLORAMPHENICOL

ACTIVE MOIETY

Comments:

Colourless to greyish white or yellowish white, needle-like crystals or elongated plates or a crystalline powder; odourless.

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC