CYCLOBENZAPRINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H21N
Molecular Weight	275.3874
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CYCLOBENZAPRINE

Structure Search

SMILES

CN(C)CCC=C1C2=C(C=CC=C2)C=CC3=C1C=CC=C3

InChI

InChIKey=JURKNVYFZMSNLP-UHFFFAOYSA-N

InChI=1S/C20H21N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-14H,7,15H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C20H21N
Molecular Weight	275.3874
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:16:52 UTC 2023` Edited by `admin` on `Sat Dec 16 16:16:52 UTC 2023`
Record UNII	69O5WQQ5TI
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CYCLOBENZAPRINE

Official Name

English

CYCLOBENZAPRINE [MI]

Common Name

English

MK-130 (AS THE BASE)

Code

English

Cyclobenzaprine [WHO-DD]

Common Name

English

MK-130

Systematic Name

English

cyclobenzaprine [INN]

Common Name

English

CYCLOBENZAPRINE [VANDF]

Common Name

English

CYCLOBENZAPRINE [USP IMPURITY]

Common Name

English

N,N-DIMETHYL-5H-DIBENZO(A,D)CYCLOHEPTENE-(SUP .DELTA.5,.GAMMA.)-PROPYLAMINE

Common Name

English

TNX-102

Code

English

AMITRIPTYLINE HYDROCHLORIDE IMPURITY B [EP IMPURITY]

Common Name

English

NORTRIPTYLINE HYDROCHLORIDE IMPURITY E [EP IMPURITY]

Common Name

English

1-PROPANAMINE, 3-(5H-DIBENZO(A,D)CYCLOHEPTEN-5-YLIDENE)-N,N-DIMETHYL-

Systematic Name

English

3-(5H-DIBENZO(A,D)(7)ANNULEN-5-YLIDENE)-N,N-DIMETHYLPROPAN-1-AMINE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29696

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

NDF-RT

N0000175737

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

NDF-RT

N0000175730

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

WHO-VATC

QM03BX08

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

LIVERTOX

NBK548894

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

WHO-ATC

M03BX08

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

Code System Code Type Description

LACTMED

Cyclobenzaprine

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

EVMPD

SUB06849MIG

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

FDA UNII

69O5WQQ5TI

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

DRUG CENTRAL

751

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

WIKIPEDIA

CYCLOBENZAPRINE

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

ECHA (EC/EINECS)

206-145-8

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

ChEMBL

CHEMBL669

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

MERCK INDEX

m3976

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

Merck Index

IUPHAR

7152

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

SMS_ID

100000083730

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

DRUG BANK

DB00924

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

CAS

303-53-7

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

HSDB

8305

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

INN

791

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

MESH

C004704

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

NCI_THESAURUS

C28947

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

CHEBI

3996

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

DAILYMED

69O5WQQ5TI

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

RXCUI

21949

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

RxNorm

PUBCHEM

2895

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

EPA CompTox

DTXSID0046933

Created by admin on Sat Dec 16 16:16:53 UTC 2023 , Edited by admin on Sat Dec 16 16:16:53 UTC 2023

PRIMARY

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SALT/SOLVATE -> PARENT


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METABOLIC ENZYME -> INHIBITOR

Qualification:

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METABOLITE -> PARENT


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METABOLITE -> PARENT


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METABOLITE -> PARENT


					T6JP526G33

2-HYDROXYCYCLOBENZAPRINE

METABOLITE -> PARENT


					T6X8KQ83F4

NORCYCLOBENZAPRINE

METABOLITE -> PARENT

Interaction Type:

MAJOR


					85C2J6324P

CYCLOBENZAPRINE N-GLUCURONIDE

METABOLITE -> PARENT


					7TP3TV1XES

CYCLOBENZAPRINE N-OXIDE

METABOLITE -> PARENT

Related Record Type Details


					26LUD4JO9K

AMITRIPTYLINE HYDROCHLORIDE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					26LUD4JO9K

AMITRIPTYLINE HYDROCHLORIDE

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					00FN6IH15D

NORTRIPTYLINE HYDROCHLORIDE

PARENT -> IMPURITY

Comments:

UNSPECIFIED

Qualification:

EP

Related Record Type Details


					69O5WQQ5TI

CYCLOBENZAPRINE

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Route of Elimination	PHARMACOKINETIC				EXCRETED UNCHANGED, RENAL PHARMACOKINETIC

PROTEIN BINDING	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC				ORAL, EXTENDED-RELEASE PHARMACOKINETIC ORAL, EXTENDED-RELEASE (ELDERLY OLDER THAN 65 YEARS) PHARMACOKINETIC

ORAL BIOAVAILABILITY	PHARMACOKINETIC

Tmax	PHARMACOKINETIC				ORAL, EXTENDED-RELEASE CAPSULE (15 mg DOSE) PHARMACOKINETIC ORAL, EXTENDED-RELEASE CAPSULE (30 mg DOSE) PHARMACOKINETIC