ICOSAPENT ETHYL

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H34O2
Molecular Weight	330.5042
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	5
Charge	0

SHOW SMILES / InChI

Structure of ICOSAPENT ETHYL

Structure Search

SMILES

CCOC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CC

InChI

InChIKey=SSQPWTVBQMWLSZ-AAQCHOMXSA-N

InChI=1S/C22H34O2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24-4-2/h5-6,8-9,11-12,14-15,17-18H,3-4,7,10,13,16,19-21H2,1-2H3/b6-5-,9-8-,12-11-,15-14-,18-17-

HIDE SMILES / InChI

Molecular Formula	C22H34O2
Molecular Weight	330.5042
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	5
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:39:15 UTC 2023` Edited by `admin` on `Fri Dec 15 15:39:15 UTC 2023`
Record UNII	6GC8A4PAYH
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ICOSAPENT ETHYL

Official Name

English

AMR-101

Code

English

EICOSAPENTAENOIC ACID ETHYL ESTER

Systematic Name

English

AMR 101

Code

English

Eicosapentaenoic acid ethyl ester [WHO-DD]

Common Name

English

ETHYL EICOSAPENTAENOIC ACID

Systematic Name

English

ICOSAPENT ETHYL [ORANGE BOOK]

Common Name

English

VASCEPA

Brand Name

English

ETHYL ICOSAPENT

Common Name

English

ETHYL ICOSAPENTATE

Common Name

English

ETHYL EICOSAPENTAENOATE

Systematic Name

English

EICOSAPENTAENOIC ACID ETHYL ESTER [MART.]

Common Name

English

5,8,11,14,17-EICOSAPENTAENOIC ACID, ETHYL ESTER, (5Z,8Z,11Z,14Z,17Z)-

Common Name

English

ETHYL ALL-CIS-5,8,11,14,17-ICOSAPENTAENOIC ACID

Common Name

English

TIMNODONIC ACID ETHYL ESTER

Common Name

English

NSC-759597

Code

English

AMR101

Code

English

EPADEL

Common Name

English

ICOSAPENT ETHYL [VANDF]

Common Name

English

Ethyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate

Systematic Name

English

ICOSAPENT ETHYL [USAN]

Common Name

English

EICOSAPENTAENOIC ACID ETHYL ESTER [USP-RS]

Common Name

English

EICOSAPENTAENOIC ACID ETHYL ESTER [MI]

Common Name

English

ICOSAPENT ETHYL ESTER

Common Name

English

ETHYL ICOSAPENTATE [JAN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

134300

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

EU-Orphan Drug

EU/3/00/013

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

NCI_THESAURUS

C29703

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

Code System Code Type Description

DRUG BANK

DB08887

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

CHEBI

84883

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

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RS_ITEM_NUM

1234307

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

NSC

759597

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

PUBCHEM

9831415

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

EPA CompTox

DTXSID601018686

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

ChEMBL

CHEMBL2095209

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

USAN

YY-57

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

FDA UNII

6GC8A4PAYH

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

DRUG CENTRAL

1413

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

EVMPD

SUB32403

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

CAS

86227-47-6

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

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MERCK INDEX

m4848

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

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Merck Index

ChEMBL

CHEMBL1200711

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

RXCUI

1304974

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

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RxNorm

SMS_ID

100000124506

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

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DAILYMED

6GC8A4PAYH

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

NCI_THESAURUS

C72986

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

WIKIPEDIA

ETHYL EICOSAPENTAENOIC ACID

Created by admin on Fri Dec 15 15:39:15 UTC 2023 , Edited by admin on Fri Dec 15 15:39:15 UTC 2023

PRIMARY

Related Record Type Details


					AAN7QOV9EA

ICOSAPENT

METABOLITE ACTIVE -> PARENT

Comments:

EPA is mainly metabolized by the liver via beta-oxidation similar to dietary fatty acids. Beta oxidation splits the long carbon chain of EPA into acetyl Coenzyme A, which is converted into energy via the Krebs cycle. Cytochrome P450-mediated metabolism is a minor pathway of elimination of EPA.

Interaction Type:

MAJOR

Qualification:

PLASMA

Related Record Type Details


					AAN7QOV9EA

ICOSAPENT

ACTIVE MOIETY