U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C20H30O2
Molecular Weight 302.451
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 5
Charge 0

SHOW SMILES / InChI
Structure of ICOSAPENT

SMILES

CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O

InChI

InChIKey=JAZBEHYOTPTENJ-JLNKQSITSA-N
InChI=1S/C20H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22)/b4-3-,7-6-,10-9-,13-12-,16-15-

HIDE SMILES / InChI
Molecular Formula C20H30O2
Molecular Weight 302.451
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 5
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:35:07 UTC 2023
Edited
by admin
on Fri Dec 15 16:35:07 UTC 2023
Record UNII
AAN7QOV9EA
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ICOSAPENT
INN  
INN  
Official Name English
EPA
Common Name English
EICOSAPENTAENOIC ACID (EPA) (C20:5) (CONSTITUENT OF KRILL OIL) [DSC]
Common Name English
TIMNODONIC ACID
Common Name English
Eicosapentaenoic acid [WHO-DD]
Common Name English
ALL-CIS-FATTY ACID 20:5 OMEGA-3
Common Name English
INCROMEGA E 7010SR
Common Name English
ROPUFA 70
Common Name English
icosapent [INN]
Common Name English
(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-EICOSAPENTAENOIC ACID
Systematic Name English
(ALL-Z)-5,8,11,14,17-EICOSAPENTAENOIC ACID
Common Name English
EICOSAPENTAENOATE
Systematic Name English
EICOSAPENTAENOIC ACID [INCI]
Common Name English
EICOSAPENTAENOIC ACID [MI]
Common Name English
EICOSAPENTAENOIC ACID (EPA) (C20:5 N3)
Common Name English
EICOSAPENTAENOIC ACID [USP-RS]
Common Name English
C20:5 (N-3)
Common Name English
EICOSAPENTAENOIC ACID
INCI   MART.   MI   VANDF   WHO-DD  
INCI  
Official Name English
EICOSAPENTAENOIC ACID (C20:5 N3)
Common Name English
EICOSAPENTAENOIC ACID [VANDF]
Common Name English
EICOSAPENTAENOIC ACID [MART.]
Common Name English
EPA 45G
Code English
Classification Tree Code System Code
LOINC 75097-6
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
LOINC 88998-0
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
FDA ORPHAN DRUG 283409
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
LOINC 90911-9
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
LIVERTOX 342
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
EU-Orphan Drug EU/3/09/666
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
LOINC 88996-4
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
NCI_THESAURUS C67080
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
DSLD 3820 (Number of products:4)
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
LOINC 35173-4
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
LOINC 90908-5
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
DSLD 1011 (Number of products:2641)
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
LOINC 90909-3
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
LOINC 88999-8
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
LOINC 88997-2
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
LOINC 90912-7
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
Code System Code Type Description
CHEBI
36006
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
RS_ITEM_NUM
1234293
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
SMS_ID
100000079270
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
MESH
D015118
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
FDA UNII
AAN7QOV9EA
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
CHEBI
28364
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
INN
6328
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
CAS
10417-94-4
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
WIKIPEDIA
EICOSAPENTAENOIC ACID
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
ChEMBL
CHEMBL460026
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
CHEBI
61330
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
EPA CompTox
DTXSID9041023
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
DAILYMED
AAN7QOV9EA
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
DRUG CENTRAL
3174
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
EVMPD
SUB13664MIG
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
CAS
25378-27-2
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
NON-SPECIFIC SUBSTITUTION
MERCK INDEX
m4848
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY Merck Index
CHEBI
58562
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
CHEBI
84883
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
NCI_THESAURUS
C68434
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
CAS
1553-41-9
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
NON-SPECIFIC STEREOCHEMISTRY
RXCUI
618597
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
ALTERNATIVE
IUPHAR
7441
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
RXCUI
90
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
DRUG BANK
DB00159
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
PUBCHEM
446284
Created by admin on Fri Dec 15 16:35:07 UTC 2023 , Edited by admin on Fri Dec 15 16:35:07 UTC 2023
PRIMARY
Related Record Type Details
KRILL OIL
PARENT -> CONSTITUENT ALWAYS PRESENT
USP
Structure of ICOSAPENT SODIUM
SALT/SOLVATE -> PARENT
FISH OIL
LIPID -> FATTY ACID
Structure of ICOSABUTATE
DERIVATIVE -> PARENT
COD LIVER OIL
PARENT -> CONSTITUENT ALWAYS PRESENT
USP
Structure of Icosapent lysine salt
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of ICOSAPENT ETHYL
PARENT -> METABOLITE ACTIVE
EPA is mainly metabolized by the liver via beta-oxidation similar to dietary fatty acids. Beta oxidation splits the long carbon chain of EPA into acetyl Coenzyme A, which is converted into energy via the Krebs cycle. Cytochrome P450-mediated metabolism is a minor pathway of elimination of EPA.
MAJOR
PLASMA
Related Record Type Details
Structure of ICOSAPENT
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966