Vancomycin

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NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C66H75Cl2N9O24
Molecular Weight	1449.254
Optical Activity	UNSPECIFIED
Defined Stereocenters	18 / 18
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of Vancomycin

Structure Search

SMILES

[H][C@@]2(O[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1)[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2OC3=C4OC5=CC=C(C=C5Cl)[C@@H](O)[C@@H](NC(=O)[C@@H](CC(C)C)NC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]6C(C=C3OC7=C(Cl)C=C(C=C7)[C@@H](O)[C@@H]8NC(=O)[C@H](NC6=O)C9=CC(=C(O)C=C9)C%10=C(C=C(O)C=C%10O)[C@H](NC8=O)C(O)=O)=C4

InChI

InChIKey=MYPYJXKWCTUITO-LYRMYLQWSA-N

InChI=1S/C66H75Cl2N9O24/c1-23(2)12-34(71-5)58(88)76-49-51(83)26-7-10-38(32(67)14-26)97-40-16-28-17-41(55(40)101-65-56(54(86)53(85)42(22-78)99-65)100-44-21-66(4,70)57(87)24(3)96-44)98-39-11-8-27(15-33(39)68)52(84)50-63(93)75-48(64(94)95)31-18-29(79)19-37(81)45(31)30-13-25(6-9-36(30)80)46(60(90)77-50)74-61(91)47(28)73-59(89)35(20-43(69)82)72-62(49)92/h6-11,13-19,23-24,34-35,42,44,46-54,56-57,65,71,78-81,83-87H,12,20-22,70H2,1-5H3,(H2,69,82)(H,72,92)(H,73,89)(H,74,91)(H,75,93)(H,76,88)(H,77,90)(H,94,95)/t24-,34+,35-,42+,44-,46+,47+,48-,49+,50-,51+,52+,53+,54-,56+,57+,65-,66-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C66H75Cl2N9O24
Molecular Weight	1449.254
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	18 / 18
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:07:18 UTC 2023` Edited by `admin` on `Sat Dec 16 17:07:18 UTC 2023`
Record UNII	6Q205EH1VU
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Vancomycin

Official Name

English

vancomycin [INN]

Common Name

English

VANCOMYCIN [ORANGE BOOK]

Common Name

English

VANCOMYCIN [MI]

Common Name

English

VANCOMYCIN [USP IMPURITY]

Common Name

English

VANCOMYCIN [HSDB]

Common Name

English

Vancomycin [WHO-DD]

Common Name

English

VANCOMYCIN [USP MONOGRAPH]

Common Name

English

VANCOMYCIN [MART.]

Common Name

English

Classification Tree Code System Code

LIVERTOX

NBK548881

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.2.2

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

NCI_THESAURUS

C61101

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

NDF-RT

N0000007889

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

WHO-VATC

QA07AA09

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

FDA ORPHAN DRUG

867521

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

FDA ORPHAN DRUG

361211

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

WHO-ATC

J01XA01

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

WHO-VATC

QJ01XA01

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

WHO-ATC

A07AA09

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

NDF-RT

N0000007889

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

CFR

21 CFR 862.3950

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

NDF-RT

N0000175491

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

Code System Code Type Description

EVMPD

SUB05076MIG

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

FDA UNII

6Q205EH1VU

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

PUBCHEM

14969

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

LACTMED

Vancomycin

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

DRUG CENTRAL

2807

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

MESH

D014640

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

EPA CompTox

DTXSID0042664

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

ECHA (EC/EINECS)

215-772-6

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

WIKIPEDIA

VANCOMYCIN

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

DAILYMED

6Q205EH1VU

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

CHEBI

76842

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

ChEMBL

CHEMBL262777

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

MERCK INDEX

m11386

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

Merck Index

SMS_ID

100000085801

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

CAS

1404-90-6

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

INN

680

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

RXCUI

11124

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

RxNorm

HSDB

3262

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

NCI_THESAURUS

C925

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

DRUG BANK

DB00512

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

CHEBI

28001

Created by admin on Sat Dec 16 17:07:19 UTC 2023 , Edited by admin on Sat Dec 16 17:07:19 UTC 2023

PRIMARY

Related Record Type Details


					71WO621TJD

VANCOMYCIN HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					1BVK9QMW8G

D-ALANYL-D-ALANINE

TARGET->LIGAND


					65P5WPF3BJ

METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS

TARGET ORGANISM->INHIBITOR

Amount:

Related Record Type Details


					6Q205EH1VU

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MIC	BIOLOGICAL				SUSCEPTIBILITY: INTERMEDIATE PATHOGEN: S. AUREUS

MIC	BIOLOGICAL				PATHOGEN: STREPTOCOCCI OTHER THAN S. PNEUMONIAE SUSCEPTIBILITY: SUSCEPTIBLE

MIC	BIOLOGICAL				PATHOGEN: ENTEROCOCCI AND COAGULASE-NEGATIVE STAPHYLOCOCCI SUSCEPTIBILITY: INTERMEDIATE

MIC	BIOLOGICAL				PATHOGEN: S. AUREUS SUSCEPTIBILITY: RESISTANT
MIC	BIOLOGICAL				SUSCEPTIBILITY: SUSCEPTIBLE PATHOGEN: S. AUREUS

MIC	BIOLOGICAL				SUSCEPTIBILITY: SUSCEPTIBLE PATHOGEN: ENTEROCOCCI AND COAGULASE-NEGATIVE STAPHYLOCOCCI

Biological Half-life	PHARMACOKINETIC				POPULATION: CHILDREN AND ADOLESCENTS > 3 YEARS

Volume of Distribution	PHARMACOKINETIC				POPULATION: PEDIATRICS

Biological Half-life	PHARMACOKINETIC				POPULATION: NEWBORNS

Biological Half-life	PHARMACOKINETIC				POPULATION: INFANTS AND CHILDREN 3 MONTHS TO 4 YEARS

Biological Half-life	PHARMACOKINETIC				RENAL FUNCTION: NORMAL

Volume of Distribution	PHARMACOKINETIC				POPULATION: ADULTS

Volume of Distribution	PHARMACOKINETIC				POPULATION: NEONATES

MIC	BIOLOGICAL				PATHOGEN: ENTEROCOCCI AND COAGULASE-NEGATIVE STAPHYLOCOCCI SUSCEPTIBILITY: RESISTANT

Biological Half-life	PHARMACOKINETIC				RENAL FUNCTION: END-STAGE RENAL DISEASE