FLORBETAPIR F-18

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H25FN2O3
Molecular Weight	359.425
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of FLORBETAPIR F-18

Structure Search

SMILES

CNC1=CC=C(\C=C\C2=CC=C(OCCOCCOCC[18F])N=C2)C=C1

InChI

InChIKey=YNDIAUKFXKEXSV-CRYLGTRXSA-N

InChI=1S/C20H25FN2O3/c1-22-19-7-4-17(5-8-19)2-3-18-6-9-20(23-16-18)26-15-14-25-13-12-24-11-10-21/h2-9,16,22H,10-15H2,1H3/b3-2+/i21-1

HIDE SMILES / InChI

Molecular Formula	C20H25FN2O3
Molecular Weight	359.425
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:29:50 UTC 2023` Edited by `admin` on `Sat Dec 16 17:29:50 UTC 2023`
Record UNII	6W15Z5R0RU
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FLORBETAPIR F-18

Official Name

English

florbetapir (¹⁸F) [INN]

Common Name

English

FLORBETAPIR(18-F)

Common Name

English

FLORBETAPIR F 18

Common Name

English

AV45 F-18

Common Name

English

18F-AV45

Common Name

English

AMYVID

Brand Name

English

FLORBETAPIR F-18 [USAN]

Common Name

English

Florbetapir (18f) [WHO-DD]

Common Name

English

4-((1E)-2-(6-(2-(2-(2-(18F)FLUOROETHOXY)ETHOXY)ETHOXY)PYRIDIN-3-YL)ETHENYL)-N- METHYLBENZENAMINE

Common Name

English

FLORBETAPIR (18F)

Official Name

English

FLORBETAPIR, F-18

Common Name

English

18F-AV-45

Code

English

FLORBETAPIR F-18 [ORANGE BOOK]

Common Name

English

FLORBETAPIR (18F) [EMA EPAR]

Common Name

English

AV-45 F-18

Code

English

FLORBETAPIR F 18 [MI]

Common Name

English

(18F)AV-45

Code

English

BENZENAMINE, 4-((1E)-2-(6-(2-(2-(2-(FLUORO-18F)ETHOXY)ETHOXY)ETHOXY)-3- PYRIDINYL)ETHENYL)-N- METHYL-

Common Name

English

Classification Tree Code System Code

WHO-ATC

V09AX05

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

NDF-RT

N0000177914

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

EMA ASSESSMENT REPORTS

AMYVID (AUTHORIZED: RADIONUCLIDE IMAGING)

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

NDF-RT

N0000175871

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

WHO-VATC

QV09AX05

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

Code System Code Type Description

INN

9193

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

NDF-RT

N0000175869

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

Positron Emitting Activity [MoA]

DRUG CENTRAL

4285

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

LACTMED

Florbetapir F 18

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

EVMPD

SUB33779

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

USAN

WW-07

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

DRUG BANK

DB09149

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

FDA UNII

6W15Z5R0RU

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

CHEBI

66880

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

NCI_THESAURUS

C171884

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

MESH

C545186

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

WIKIPEDIA

Florbetapir_(18F)

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

ChEMBL

CHEMBL1908919

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

EPA CompTox

DTXSID80241898

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

MERCK INDEX

m5410

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

Merck Index

CAS

956103-76-7

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

DAILYMED

6W15Z5R0RU

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

PUBCHEM

24822371

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

SMS_ID

100000127658

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

RXCUI

1427224

Created by admin on Sat Dec 16 17:29:51 UTC 2023 , Edited by admin on Sat Dec 16 17:29:51 UTC 2023

PRIMARY

RxNorm

Related Record Type Details


					042A8N37WH

HUMAN .BETA.-AMYLOID PEPTIDE (1-42)

TARGET->RADIOLIGAND

Related Record Type Details


					AWY45KCG4T

2-(2-(2-FLUOROETHOXY)ETHOXY)ETHANOL F-18

METABOLITE -> PARENT

Comments:

The metabolites have shown lower uptake in the brain and lower affinity for binding to beta amyloid thus, it is concluded that there will be minimal interference from the metabolites to the PET image from 18F-AV-45 in the brain.


					QA68TUY9BJ

N-DESMETHYL N-ACETYL FLORBETAPIR F-18

METABOLITE INACTIVE -> PARENT

Interaction Type:

IN-VIVO

Related Record Type Details


					6W15Z5R0RU

FLORBETAPIR F-18

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC