CEFTRIAXONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H18N8O7S3
Molecular Weight	554.58
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of CEFTRIAXONE

Structure Search

SMILES

[H][C@]12SCC(CSC3=NC(=O)C(=O)NN3C)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\C4=CSC(N)=N4)C(O)=O

InChI

InChIKey=VAAUVRVFOQPIGI-SPQHTLEESA-N

InChI=1S/C18H18N8O7S3/c1-25-18(22-12(28)13(29)23-25)36-4-6-3-34-15-9(14(30)26(15)10(6)16(31)32)21-11(27)8(24-33-2)7-5-35-17(19)20-7/h5,9,15H,3-4H2,1-2H3,(H2,19,20)(H,21,27)(H,23,29)(H,31,32)/b24-8-/t9-,15-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C18H18N8O7S3
Molecular Weight	554.58
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	1
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:37:21 UTC 2023` Edited by `admin` on `Fri Dec 15 15:37:21 UTC 2023`
Record UNII	75J73V1629
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CEFTRIAXONE

Official Name

English

5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-(((2-AMINO-4-THIAZOLYL)(METHOXYIMINO)ACETYL)AMINO)-8-OXO-3-(((1,2,5,6-TETRAHYDRO-2-METHYL-5,6-DIOXO-1,2,4-TRIAZIN-3-YL)THIO)METHYL)-, (6R-(6.ALPHA.,7.BETA.(Z)))-

Common Name

English

Ceftriaxone [WHO-DD]

Common Name

English

CEFTRIAXON

Common Name

English

ceftriaxone [INN]

Common Name

English

CEFTRIAXONE [MI]

Common Name

English

CEFTRIAXONE [VANDF]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QJ01DD04

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

WHO-ATC

J01DD54

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

LIVERTOX

NBK548258

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

WHO-VATC

QJ01DD54

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

WHO-ATC

J01DD63

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NCI_THESAURUS

C357

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.2.1

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

LIVERTOX

NBK548666

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000175488

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

WHO-ATC

J01DD04

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

NDF-RT

N0000011161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

EU-Orphan Drug

EU/3/14/1425

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

Code System Code Type Description

PUBCHEM

5479530

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

WIKIPEDIA

CEFTRIAXONE

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

FDA UNII

75J73V1629

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

NCI_THESAURUS

C62020

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

DRUG BANK

DB01212

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

RXCUI

2193

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

RxNorm

MERCK INDEX

m3225

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

Merck Index

ECHA (EC/EINECS)

277-405-6

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

DAILYMED

75J73V1629

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

SMS_ID

100000093034

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

IUPHAR

5326

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

LACTMED

Ceftriaxone

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

CAS

73384-59-5

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

EVMPD

SUB07431MIG

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

EPA CompTox

DTXSID0022773

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

MESH

D002443

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

INN

4923

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

CHEBI

29007

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

ChEMBL

CHEMBL161

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

DRUG CENTRAL

564

Created by admin on Fri Dec 15 15:37:21 UTC 2023 , Edited by admin on Fri Dec 15 15:37:21 UTC 2023

PRIMARY

Related Record Type Details


					023Z5BR09K

CEFTRIAXONE SODIUM

SALT/SOLVATE -> PARENT

Amount:


					R598PB148Q

CEFTRIAXONE SODIUM ANHYDROUS

SALT/SOLVATE -> PARENT

Amount:


					6A002O1K0R

INHIBITOR -> TARGET

Comments:

in vivo mechanism of action of ribaxamase, degradation of β-lactam antibiotics in the human intestine


					4HZ67LW8L7

OAT-4

TRANSPORTER -> INHIBITOR


					I81U7H57XI

OAT-1

TRANSPORTER -> INHIBITOR


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					ZWJ2Y6JZWY

OAT-3

TRANSPORTER -> INHIBITOR

Related Record Type Details


					75J73V1629

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC