LUBIPROSTONE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H32F2O5
Molecular Weight	390.4619
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12CC(=O)[C@H](CCCCCCC(O)=O)[C@@]1([H])CC[C@@](O)(O2)C(F)(F)CCCC

InChI

InChIKey=WGFOBBZOWHGYQH-MXHNKVEKSA-N

InChI=1S/C20H32F2O5/c1-2-3-11-19(21,22)20(26)12-10-15-14(16(23)13-17(15)27-20)8-6-4-5-7-9-18(24)25/h14-15,17,26H,2-13H2,1H3,(H,24,25)/t14-,15-,17-,20-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C20H32F2O5
Molecular Weight	390.4619
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:45:42 UTC 2023` Edited by `admin` on `Sat Dec 16 16:45:42 UTC 2023`
Record UNII	7662KG2R6K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LUBIPROSTONE

Official Name

English

AMITIZA

Brand Name

English

LUBIPROSTONE [JAN]

Common Name

English

RU-0211

Code

English

lubiprostone [INN]

Common Name

English

Lubiprostone [WHO-DD]

Common Name

English

7-[(2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl]heptanoic acid

Systematic Name

English

LUBIPROSTONE [USAN]

Common Name

English

(-)-7-((2R,4AR,5R,7AR)-2-(1,1-DIFLUOROPENTYL)-2-HYDROXY-6-OXOOCTAHYDROCYCLOPENTA(B)PYRAN-5-YL)HEPTANOIC ACID

Common Name

English

LUBIPROSTONE [VANDF]

Common Name

English

LUBIPROSTONE [ORANGE BOOK]

Common Name

English

LUBIPROSTONE [MI]

Common Name

English

PROSTAN-1-OIC ACID, 16,16-DIFLUORO-11-HYDROXY-9,15-DIOXO-, (11.ALPHA.)-

Common Name

English

LUBIPROSTONE [MART.]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000175456

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

WHO-VATC

QA06AX03

Created by admin on Sat Dec 16 16:45:43 UTC 2023 , Edited by admin on Sat Dec 16 16:45:43 UTC 2023

WHO-ATC

A06AX03

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

LIVERTOX

NBK548000

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

NCI_THESAURUS

C78568

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

NDF-RT

N0000175573

Created by admin on Sat Dec 16 16:45:43 UTC 2023 , Edited by admin on Sat Dec 16 16:45:43 UTC 2023

Code System Code Type Description

SMS_ID

100000124449

Created by admin on Sat Dec 16 16:45:43 UTC 2023 , Edited by admin on Sat Dec 16 16:45:43 UTC 2023

PRIMARY

ChEMBL

CHEMBL1201134

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

PUBCHEM

157920

Created by admin on Sat Dec 16 16:45:43 UTC 2023 , Edited by admin on Sat Dec 16 16:45:43 UTC 2023

PRIMARY

MERCK INDEX

m6919

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

Merck Index

DAILYMED

7662KG2R6K

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

INN

8254

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

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RXCUI

623033

Created by admin on Sat Dec 16 16:45:43 UTC 2023 , Edited by admin on Sat Dec 16 16:45:43 UTC 2023

PRIMARY

RxNorm

WIKIPEDIA

Lubiprostone

Created by admin on Sat Dec 16 16:45:43 UTC 2023 , Edited by admin on Sat Dec 16 16:45:43 UTC 2023

PRIMARY

DRUG CENTRAL

4123

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

DRUG BANK

DB01046

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

MESH

C506401

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

IUPHAR

4242

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

CAS

333963-40-9

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

ALTERNATIVE

FDA UNII

7662KG2R6K

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

EVMPD

SUB32077

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

EPA CompTox

DTXSID5048639

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

USAN

NN-66

Created by admin on Sat Dec 16 16:45:43 UTC 2023 , Edited by admin on Sat Dec 16 16:45:43 UTC 2023

PRIMARY

NCI_THESAURUS

C66040

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

LACTMED

Lubiprostone

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

CAS

136790-76-6

Created by admin on Sat Dec 16 16:45:42 UTC 2023 , Edited by admin on Sat Dec 16 16:45:42 UTC 2023

PRIMARY

Related Record Type Details


					7662KG2R6K

LUBIPROSTONE

EXCRETED UNCHANGED

Comments:

The radioactive dose was primarily excreted in urine via the kidneys (63% of the radiolabeled dose), while around 32% of the radiolabeled dose was excreted in feces.

Amount: