INDINAVIR SULFATE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C36H47N5O4.H2O4S
Molecular Weight	711.868
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of INDINAVIR SULFATE

Structure Search

SMILES

OS(O)(=O)=O.CC(C)(C)NC(=O)[C@@H]1CN(CC2=CN=CC=C2)CCN1C[C@@H](O)C[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H]4[C@H](O)CC5=C4C=CC=C5

InChI

InChIKey=NUBQKPWHXMGDLP-BDEHJDMKSA-N

InChI=1S/C36H47N5O4.H2O4S/c1-36(2,3)39-35(45)31-24-40(22-26-12-9-15-37-21-26)16-17-41(31)23-29(42)19-28(18-25-10-5-4-6-11-25)34(44)38-33-30-14-8-7-13-27(30)20-32(33)43;1-5(2,3)4/h4-15,21,28-29,31-33,42-43H,16-20,22-24H2,1-3H3,(H,38,44)(H,39,45);(H2,1,2,3,4)/t28-,29+,31+,32-,33+;/m1./s1

HIDE SMILES / InChI

Molecular Formula	H2O4S
Molecular Weight	98.078
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C36H47N5O4
Molecular Weight	613.7895
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:56:04 UTC 2023` Edited by `admin` on `Fri Dec 15 15:56:04 UTC 2023`
Record UNII	771H53976Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

INDINAVIR SULFATE

Official Name

English

CRIXIVAN

Brand Name

English

L-735524

Code

English

INDINAVIR SULFATE [WHO-IP]

Common Name

English

INDINAVIR SULFATE [VANDF]

Common Name

English

INDINAVIR SULFATE [MI]

Common Name

English

D-ERYTHRO-PENTONAMIDE, 2,3,5-TRIDEOXY-N-(2,3-DIHYDRO-2-HYDROXY-1H-INDEN-1-YL)-5-(2-(((1,1-DIMETHYLETHYL)AMINO)CARBONYL)-4-(3-PYRIDINYLMETHYL)-1-PIPERAZINYL)-2-(PHENYLMETHYL)-, (1(1S,2R,5(S))-, SULFATE (1:1) (SALT)

Common Name

English

INDINAVIR SULPHATE [EMA EPAR]

Common Name

English

Indinavir sulfate [WHO-DD]

Common Name

English

NSC-697197

Code

English

MK-639

Code

English

INDINAVIRI SULFAS [WHO-IP LATIN]

Common Name

English

(.ALPHA.R,.GAMMA.S,2S)-.ALPHA.-BENZYL-2-(TERT-BUTYLCARBAMOYL)-.GAMMA.-HYDROXY-N-((1S,2R)-2-HYDROXY-1-INDANYL)-4-(3-PYRIDYLMETHYL)-1-PIPERAZINEVALERAMIDE SULPHATE (1:1) (SALT)

Common Name

English

D-ERYTHRO-PENTONAMIDE, 2,3,5-TRIDEOXY-N-(2,3-DIHYDRO-2-HYDROXY-1H-INDEN-1-YL)-5-(2-(((1,1-DIMETHYLETHYL)AMINO)CARBONYL)-4-(3-PYRIDINYLMETHYL)-1-PIPERAZINYL)-2-(PHENYLMETHYL)-, (1(1S,2R,5(S))-, SULPHATE (1:1) (SALT)

Common Name

English

L-735,524

Code

English

INDINAVIR SULFATE [USAN]

Common Name

English

INDINAVIR SULFATE [MART.]

Common Name

English

(αR,γS,2S)-α-Benzyl-2-(tert-butylcarbamoyl)-γ-hydroxy-N-[(1S,2R)-2-hydroxy-1-indanyl]-4-(3-pyridylmethyl)-1-piperazinevaleramide sulfate (1:1) (salt)

Common Name

English

INDINAVIR SULFATE [ORANGE BOOK]

Common Name

English

INDINAVIR SULPHATE

Common Name

English

INDINAVIR SULFATE [HSDB]

Common Name

English

INDINAVIR SULFATE [USP MONOGRAPH]

Common Name

English

Classification Tree Code System Code

EMA ASSESSMENT REPORTS

CRIXIVAN (AUTHORIZED: HIV INFECTIONS)

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

NCI_THESAURUS

C97366

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

Code System Code Type Description

PUBCHEM

5462355

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

CAS

157810-81-6

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

FDA UNII

771H53976Q

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

SMS_ID

100000086983

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

EPA CompTox

DTXSID1044221

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

HSDB

7158

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

NCI_THESAURUS

C1662

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

NSC

697197

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

DRUG BANK

DBSALT000338

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

DAILYMED

771H53976Q

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

USAN

HH-15

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

ChEMBL

CHEMBL115

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

WHO INTERNATIONAL PHARMACOPEIA

INDINAVIR SULFATE

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

Description: A white or almost white powder. Solubility: Freely soluble in water, soluble in methanol. Category: Antiretroviral (protease inhibitor). Storage: Indinavir sulfate should be kept in a tightly closed container, protected from light.Additional information: Indinavir sulfate occurs as the monoethanolate which is hygroscopic. It converts to the hydrate upon loss of ethanol and exposure to moist air. Definition: Indinavir sulfate contains not less than 98.5% and not more than 101.0% of (C36H47N5O4,H2O4S), calculated with reference to the anhydrous and ethanol free substance.

MERCK INDEX

m6253

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

Merck Index

RXCUI

203153

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

RxNorm

EVMPD

SUB02666MIG

Created by admin on Fri Dec 15 15:56:04 UTC 2023 , Edited by admin on Fri Dec 15 15:56:04 UTC 2023

PRIMARY

Related Record Type Details


					34OB95C8AE

INDINAVIR SULFATE ETHANOLATE

SALT/SOLVATE -> PARENT


					34OB95C8AE

INDINAVIR SULFATE ETHANOLATE

SUBSTANCE->BASIS OF STRENGTH


					771H53976Q

INDINAVIR SULFATE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

USP

Amount:


					34OB95C8AE

INDINAVIR SULFATE ETHANOLATE

SOLVATE->ANHYDROUS

Related Record Type Details


					98N2VRY18Z

DESNICOTINYL INDINAVIR

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					H89N2P83I5

DIINDANYL INDINAVIR

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					4L1DMF47VA

INDINAVIR LACTONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					53K77K57XZ

(2S)-N-(1,1-DIMETHYLETHYL)PIPERAZINE-2-CARBOXAMIDE

IMPURITY -> PARENT


					LU3GK925A8

1-AMINO-2-INDANOL, CIS-(-)-

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					59JB7S9VY9

N-(N,O-ISOPROPYLIDENE-(2R)-HYDROXY INDAN-(1S)-YL)-(2R)-BENZYL-(4S,5)-EPOXY PENTANAMIDE

IMPURITY -> PARENT


					AUG7A0JP5E

INDINAVIR, THREO-

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:

Related Record Type Details


					9MG78X43ZT

INDINAVIR ANHYDROUS

ACTIVE MOIETY