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Details

Stereochemistry ACHIRAL
Molecular Formula C7H6ClN3O4S2
Molecular Weight 295.723
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHLOROTHIAZIDE

SMILES

NS(=O)(=O)C1=C(Cl)C=C2N=CNS(=O)(=O)C2=C1

InChI

InChIKey=JBMKAUGHUNFTOL-UHFFFAOYSA-N
InChI=1S/C7H6ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-3H,(H,10,11)(H2,9,12,13)

HIDE SMILES / InChI
Molecular Formula C7H6ClN3O4S2
Molecular Weight 295.723
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:17:37 UTC 2023
Edited
by admin
on Fri Dec 15 15:17:37 UTC 2023
Record UNII
77W477J15H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CHLOROTHIAZIDE
EP   GREEN BOOK   HSDB   INN   JAN   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD  
INN  
Official Name English
CHLOROTHIAZIDE [ORANGE BOOK]
Common Name English
CHLOROTHIAZIDE [VANDF]
Common Name English
CHLOROTHIAZIDE [JAN]
Common Name English
6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Systematic Name English
CHLOROTHIAZIDE [GREEN BOOK]
Common Name English
DIURIL
Brand Name English
HYDROCHLOROTHIAZIDE IMPURITY, CHLOROTHIAZIDE- [USP IMPURITY]
Common Name English
CHLOROTHIAZIDE [HSDB]
Common Name English
NSC-25693
Code English
2H-1,2,4-BENZOTHIADIAZINE-7-SULFONAMIDE, 6-CHLORO-, 1,1-DIOXIDE
Systematic Name English
chlorothiazide [INN]
Common Name English
CHLOROTHIAZIDE [USP MONOGRAPH]
Common Name English
CHLOROTHIAZIDE [USP IMPURITY]
Common Name English
CHLOROTHIAZIDE [MART.]
Common Name English
HYDROCHLOROTHIAZIDE IMPURITY A [EP IMPURITY]
Common Name English
Chlorothiazide [WHO-DD]
Common Name English
CHLOROTHIAZIDE [MI]
Common Name English
CHLOROTHIAZIDE [EP IMPURITY]
Common Name English
Classification Tree Code System Code
WHO-ATC C03AB04
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
WHO-ATC C03AA04
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
NDF-RT N0000166469
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
WHO-VATC QC03AB04
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
NCI_THESAURUS C49185
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
NDF-RT N0000175419
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
CFR 21 CFR 520.420
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
WHO-VATC QC03AA04
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
NDF-RT N0000166469
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
LIVERTOX 194
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
WHO-VATC QC03AH01
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
NDF-RT N0000175359
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
WHO-ATC C03AH01
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
Code System Code Type Description
FDA UNII
77W477J15H
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
CHEBI
3640
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
INN
636
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
EVMPD
SUB06198MIG
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
MESH
D002740
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
WIKIPEDIA
CHLOROTHIAZIDE
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
HSDB
3030
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
DAILYMED
77W477J15H
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-404-9
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
DRUG BANK
DB00880
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
EPA CompTox
DTXSID0022800
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
LACTMED
Chlorothiazide
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
CAS
58-94-6
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
ChEMBL
CHEMBL842
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
MERCK INDEX
m3441
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY Merck Index
DRUG CENTRAL
609
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
RS_ITEM_NUM
1121005
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
SMS_ID
100000081850
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
RXCUI
2396
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY RxNorm
IUPHAR
4835
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
NSC
25693
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
NCI_THESAURUS
C28924
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
PUBCHEM
2720
Created by admin on Fri Dec 15 15:17:37 UTC 2023 , Edited by admin on Fri Dec 15 15:17:37 UTC 2023
PRIMARY
Related Record Type Details
Structure of CHLOROTHIAZIDE HYDROCHLORIDE
SALT/SOLVATE -> PARENT
OAT-1
TRANSPORTER -> INHIBITOR
OAT-4
TRANSPORTER -> INHIBITOR
OAT-2
TRANSPORTER -> INHIBITOR
Structure of N-(2-AMINO-4-CHLORO-5-SULFAMOYL-PHENYL)SULFONYLFORMAMIDE
DEGRADENT -> PARENT
CARBONIC ANHYDRASE 1
TARGET -> INHIBITOR
OAT-3
TRANSPORTER -> INHIBITOR
Structure of CHLOROTHIAZIDE SODIUM
SALT/SOLVATE -> PARENT
Structure of 4-Chloro-6-(formylamino)-1,3-benzenedisulfonamide
DEGRADENT -> PARENT
Produced thru Hydrolytic degradation in acidic conditions.
Related Record Type Details
Structure of CHLOROTHIAZIDE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of HYDROCHLOROTHIAZIDE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of CHLOROTHIAZIDE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
NIH
NCATS
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