LOMUSTINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H16ClN3O2
Molecular Weight	233.695
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LOMUSTINE

Structure Search

SMILES

ClCCN(N=O)C(=O)NC1CCCCC1

InChI

InChIKey=GQYIWUVLTXOXAJ-UHFFFAOYSA-N

InChI=1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)

HIDE SMILES / InChI

Molecular Formula	C9H16ClN3O2
Molecular Weight	233.695
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:15:59 UTC 2023` Edited by `admin` on `Fri Dec 15 16:15:59 UTC 2023`
Record UNII	7BRF0Z81KG
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

LOMUSTINE

Official Name

English

LOMUSTINE [USP MONOGRAPH]

Common Name

English

1-(2-CHLOROETHYL)-3-CYCLOHEXYL-1-NITROSOUREA [IARC]

Common Name

English

1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea

Systematic Name

English

LOMUSTINE [HSDB]

Common Name

English

LOMUSTINE [EP MONOGRAPH]

Common Name

English

CEENU

Brand Name

English

CCN-U

Code

English

LOMUSTINE [MART.]

Common Name

English

CCNU

Code

English

LOMUSTINE [VANDF]

Common Name

English

UREA, N-(2-CHLOROETHYL)-N'-CYCLOHEXYL-N-NITROSO-

Systematic Name

English

LOMUSTINE [USP-RS]

Common Name

English

LOMUSTINE [ORANGE BOOK]

Common Name

English

Lomustine [WHO-DD]

Common Name

English

NSC-79037

Code

English

LOMUSTINE [USAN]

Common Name

English

LOMUSTINE [MI]

Common Name

English

lomustine [INN]

Common Name

English

Classification Tree Code System Code

LIVERTOX

NBK548631

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

NCI_THESAURUS

C699

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

NDF-RT

N0000000236

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

WHO-VATC

QL01AD02

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

WHO-ATC

L01AD02

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

NDF-RT

N0000175558

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

Code System Code Type Description

SMS_ID

100000082024

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

EVMPD

SUB08567MIG

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

CAS

13010-47-4

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

MERCK INDEX

m6891

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

Merck Index

PUBCHEM

3950

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

EPA CompTox

DTXSID2023222

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

DRUG CENTRAL

1596

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

DAILYMED

7BRF0Z81KG

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

RXCUI

6466

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

RxNorm

HSDB

6519

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

WIKIPEDIA

LOMUSTINE

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

MESH

D008130

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

IUPHAR

7214

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

NCI_THESAURUS

C617

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

DRUG BANK

DB01206

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

NSC

79037

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

RS_ITEM_NUM

1369419

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

ECHA (EC/EINECS)

235-859-2

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

CHEBI

6520

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

INN

3184

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

FDA UNII

7BRF0Z81KG

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

ChEMBL

CHEMBL514

Created by admin on Fri Dec 15 16:15:59 UTC 2023 , Edited by admin on Fri Dec 15 16:15:59 UTC 2023

PRIMARY

Related Record Type Details


					7BRF0Z81KG

LOMUSTINE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

EP

Amount:

Related Record Type Details


					ZV7823VVIM

1,3-DICYCLOHEXYLUREA

IMPURITY -> PARENT

Comments:

No more than one such impurity (carmustine related compound A, lomustine related compound B, or lomustine related compound C) is greater than 0.2%.

Interaction Type:

CHROMATOGRAPHIC PURITY (TLC)

Qualification:

USP

Amount:


					3PU8X9N1UI

3-(2-CHLOROETHYL)-1-CYCLOHEXYL-1-NITROSOUREA

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					ZV7823VVIM

1,3-DICYCLOHEXYLUREA

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					C001066WH2

1-(2-CHLOROETHYL)-3-CYCLOHEXYLUREA

IMPURITY -> PARENT

Comments:

No more than one such impurity (carmustine related compound A, lomustine related compound B, or lomustine related compound C) is greater than 0.2%.

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					67617YV44S

1,3-BIS(2-CHLOROETHYL)UREA

IMPURITY -> PARENT

Comments:

No more than one such impurity (carmustine related compound A, lomustine related compound B, or lomustine related compound C) is greater than 0.2%.

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					67617YV44S

1,3-BIS(2-CHLOROETHYL)UREA

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					C001066WH2

1-(2-CHLOROETHYL)-3-CYCLOHEXYLUREA

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					7BRF0Z81KG

LOMUSTINE

ACTIVE MOIETY