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Details

Stereochemistry ACHIRAL
Molecular Formula C26H29NO.C6H8O7
Molecular Weight 563.6381
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of TAMOXIFEN CITRATE

SMILES

OC(=O)CC(O)(CC(O)=O)C(O)=O.CC\C(=C(/C1=CC=CC=C1)C2=CC=C(OCCN(C)C)C=C2)C3=CC=CC=C3

InChI

InChIKey=FQZYTYWMLGAPFJ-OQKDUQJOSA-N
InChI=1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-;

HIDE SMILES / InChI
Molecular Formula C26H29NO
Molecular Weight 371.5146
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE
Molecular Formula C6H8O7
Molecular Weight 192.1235
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:21:03 UTC 2023
Edited
by admin
on Fri Dec 15 15:21:03 UTC 2023
Record UNII
7FRV7310N6
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TAMOXIFEN CITRATE
EP   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
USAN  
Official Name English
NOLVADEX
Brand Name English
NOURYTAM
Common Name English
TAMOFENE
Brand Name English
SOLTAMOX
Brand Name English
ETHANAMINE, 2-(4-(1,2-DIPHENYL-1-BUTENYL)PHENOXY)-N,N-DIMETHYL, (Z)-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1)
Common Name English
TAMOXIFEN CITRATE [MI]
Common Name English
TAMOXIFEN CITRATE [WHO-IP]
Common Name English
TAMOXIFEN CITRATE [USAN]
Common Name English
TAMOXIFEN CITRATE [ORANGE BOOK]
Common Name English
TAMOXIFEN CITRATE [MART.]
Common Name English
TOMAXASTA
Common Name English
ICI-46474
Code English
TAMOXIFEN CITRATE [VANDF]
Common Name English
ZITAZONIUM
Brand Name English
I.C.I.46474 CITRATE
Code English
NSC-180973
Code English
KESSAR
Brand Name English
NSC-757345
Code English
TAMOXIFEN CITRATE [EP MONOGRAPH]
Common Name English
ICI 46,474
Code English
TAMOXIFEN CITRATE [USP-RS]
Common Name English
TAMOXIFEN CITRATE [USP MONOGRAPH]
Common Name English
TAMOXIFEN CITRATE [JAN]
Common Name English
ZEMIDE
Brand Name English
(Z)-2-(P-(1,2-DIPHENYL-1-BUTENYL)PHENOXY)-N,N-DIMETHYLETHYLAMINE CITRATE (1:1)
Common Name English
TAMOXIFENI CITRAS [WHO-IP LATIN]
Common Name English
Tamoxifen citrate [WHO-DD]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C1821
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
NCI_THESAURUS C2089
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
EU-Orphan Drug EU/3/17/1944
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
Code System Code Type Description
EVMPD
SUB04672MIG
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
RXCUI
40137
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY RxNorm
ChEMBL
CHEMBL83
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
DAILYMED
7FRV7310N6
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
CHEBI
9397
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
PUBCHEM
2733525
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
DRUG BANK
DBSALT000168
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
MERCK INDEX
m10450
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY Merck Index
WHO INTERNATIONAL PHARMACOPEIA
TAMOXIFEN CITRATE
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY Description: A white or almost white, crystalline powder. Solubility: Slightly soluble in water and acetone R; soluble in methanol R. Category: Antiestrogen. Storage: Tamoxifen citrate should be kept in a well-closed container, protected from light. Requirement: Tamoxifen citrate contains not less than 99.0% and not more than the equivalent of 101.0% of C26H29NO,C6H8O7, calculated with reference to the dried substance.
ECHA (EC/EINECS)
259-415-2
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
NCI_THESAURUS
C855
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
NSC
180973
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
CAS
54965-24-1
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
FDA UNII
7FRV7310N6
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
EPA CompTox
DTXSID8021301
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
NSC
757345
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
SMS_ID
100000090201
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
RS_ITEM_NUM
1643306
Created by admin on Fri Dec 15 15:21:03 UTC 2023 , Edited by admin on Fri Dec 15 15:21:03 UTC 2023
PRIMARY
Related Record Type Details
Structure of TAMOXIFEN
PARENT -> SALT/SOLVATE
Structure of TAMOXIFEN CITRATE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
EP
Structure of ANHYDROUS CITRIC ACID
PARENT -> SALT/SOLVATE
Structure of TAMOXIFEN CITRATE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
USP
Related Record Type Details
DESETHYL TAMOXIFEN
IMPURITY -> PARENT
UNSPECIFIED
EP
DESETHYL METHYL TAMOXIFEN
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of N-DESMETHYLTAMOXIFEN
IMPURITY -> PARENT
not more than 3 times the area of the principal peak in the chromatogram obtained with reference solution (b)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 4-(4-(2-(DIMETHYLAMINO)ETHOXY)DIPHENYLMETHYL) TAMOXIFEN
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 1-(4-(2-(DIMETHYLAMINO)ETHOXY)PHENYL)-2-PHENYLBUTAN-1-ONE, (2RS)-
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of TAMOXIFEN, (E)-
IMPURITY -> PARENT
not more than 3 times the area of the principal peak in the chromatogram obtained with reference solution (b)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
O-TAMOXIFEN ISOMER
IMPURITY -> PARENT
UNSPECIFIED
EP
Structure of 1-(4-(2-(DIMETHYLAMINO)ETHOXY)PHENYL)-1,2-DIPHENYLBUTAN-1-OL
IMPURITY -> PARENT
UNSPECIFIED
EP
Related Record Type Details
Structure of TAMOXIFEN
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