CEFEPIME

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H24N6O5S2
Molecular Weight	480.561
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of CEFEPIME

Structure Search

SMILES

[H][C@]12SCC(C[N+]3(C)CCCC3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\C4=CSC(N)=N4)C([O-])=O

InChI

InChIKey=HVFLCNVBZFFHBT-ZKDACBOMSA-N

InChI=1S/C19H24N6O5S2/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29)/b23-12-/t13-,17-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C19H24N6O5S2
Molecular Weight	480.561
Charge	0
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	1
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:39:58 UTC 2023` Edited by `admin` on `Sat Dec 16 16:39:58 UTC 2023`
Record UNII	807PW4VQE3
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CEFEPIME

Official Name

English

1-(((6R,7R)-7-(2-(2-AMINO-4-THIAZOLYL)GLYOXYLAMIDO)-2-CARBOXY-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-EN-3-YL)METHYL)-1-METHYLPYRROLIDINIUM HYDROXIDE, INNER SALT, 7(SUP 2)-(Z)-(O-METHYLOXIME)

Common Name

English

VNRX-5022

Code

English

Cefepime [WHO-DD]

Common Name

English

CEFEPIME [MI]

Common Name

English

cefepime [INN]

Common Name

English

CEFEPIME [USAN]

Common Name

English

PYRROLIDINIUM, 1-((7-(((2-AMINO-4-THIAZOLYL)(METHOXYIMINO)ACETYL)AMINO)-2-CARBOXY-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-EN-3-YL)METHYL)-1-METHYL-, HYDROXIDE, INNER SALT, (6R-(6.ALPHA.,7.BETA.(Z)))-

Common Name

English

CEFEPIME [VANDF]

Common Name

English

J01DE01

Code

English

BMY-28142

Code

English

Classification Tree Code System Code

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

WHO-VATC

QJ01DE01

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

WHO-ATC

J01DE01

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NCI_THESAURUS

C357

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000175488

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

LIVERTOX

NBK548666

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

LIVERTOX

NBK547862

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

WHO-ATC

J01RA06

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

NDF-RT

N0000011161

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

Code System Code Type Description

LACTMED

Cefepime

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

DRUG CENTRAL

535

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

CHEBI

478164

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

MERCK INDEX

m3193

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

Merck Index

FDA UNII

807PW4VQE3

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

CAS

88040-23-7

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

PUBCHEM

5479537

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

NCI_THESAURUS

C65294

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

DAILYMED

807PW4VQE3

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

EPA CompTox

DTXSID70873208

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

RXCUI

20481

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

RxNorm

MESH

C043266

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

INN

6092

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

ChEMBL

CHEMBL186

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

WIKIPEDIA

CEFEPIME

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

DRUG BANK

DB01413

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

USAN

X-23

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

EVMPD

SUB07390MIG

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

SMS_ID

100000081818

Created by admin on Sat Dec 16 16:39:59 UTC 2023 , Edited by admin on Sat Dec 16 16:39:59 UTC 2023

PRIMARY

Related Record Type Details


					807PW4VQE3

CEFEPIME

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


					YP33Y0FYAE

CEFEPIME SULFATE

SALT/SOLVATE -> PARENT

Amount:


					3M13XS26I8

OCTN-2

TRANSPORTER -> INHIBITOR


					I8X1O0607P

CEFEPIME HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:

Related Record Type Details


					06509TZU6C

1-METHYLPYRROLIDINE

METABOLITE INACTIVE -> PARENT

Comments:

Converted rapidly to NMP-N-oxide

Interaction Type:

MINOR

Qualification:

URINE

Amount:


					3AG3AB9JHQ

N-Methylpyrrolidine oxide

METABOLITE INACTIVE -> PARENT

Qualification:

URINE

Amount:

Related Record Type Details


					807PW4VQE3

CEFEPIME

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC