Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C22H22N2O |
| Molecular Weight | 330.4229 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@@H]1CCCN1CCC2=CC3=CC(=CC=C3O2)C4=CC=C(C=C4)C#N
InChI
InChIKey=KFHYZKCRXNRKRC-MRXNPFEDSA-N
InChI=1S/C22H22N2O/c1-16-3-2-11-24(16)12-10-21-14-20-13-19(8-9-22(20)25-21)18-6-4-17(15-23)5-7-18/h4-9,13-14,16H,2-3,10-12H2,1H3/t16-/m1/s1
| Molecular Formula | C22H22N2O |
| Molecular Weight | 330.4229 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:52:44 UTC 2023
by
admin
on
Sat Dec 16 09:52:44 UTC 2023
|
| Record UNII |
86H6B395PI
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
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Systematic Name | English |
| Code System | Code | Type | Description | ||
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9818903
Created by
admin on Sat Dec 16 09:52:44 UTC 2023 , Edited by admin on Sat Dec 16 09:52:44 UTC 2023
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PRIMARY | |||
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460746-46-7
Created by
admin on Sat Dec 16 09:52:44 UTC 2023 , Edited by admin on Sat Dec 16 09:52:44 UTC 2023
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ABT-239
Created by
admin on Sat Dec 16 09:52:44 UTC 2023 , Edited by admin on Sat Dec 16 09:52:44 UTC 2023
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DTXSID00196710
Created by
admin on Sat Dec 16 09:52:44 UTC 2023 , Edited by admin on Sat Dec 16 09:52:44 UTC 2023
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PRIMARY | |||
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86H6B395PI
Created by
admin on Sat Dec 16 09:52:44 UTC 2023 , Edited by admin on Sat Dec 16 09:52:44 UTC 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET->INVERSE AGONIST |
It was ultimately dropped from human trials after showing the dangerous cardiac side effect of QT prolongation
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
