RANITIDINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C13H22N4O3S
Molecular Weight	314.404
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of RANITIDINE

Structure Search

SMILES

CNC(NCCSCC1=CC=C(CN(C)C)O1)=C[N+]([O-])=O

InChI

InChIKey=VMXUWOKSQNHOCA-LCYFTJDESA-N

InChI=1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9-

HIDE SMILES / InChI

Molecular Formula	C13H22N4O3S
Molecular Weight	314.404
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:14:17 UTC 2023` Edited by `admin` on `Fri Dec 15 16:14:17 UTC 2023`
Record UNII	884KT10YB7
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

RANITIDINE

Official Name

English

RANITIDINE [VANDF]

Common Name

English

RANITIDINE [MI]

Common Name

English

RANITIDINE [MART.]

Common Name

English

RANITIDINE [ORANGE BOOK]

Common Name

English

RANITIDINE [USAN]

Common Name

English

NSC-757851

Code

English

Ranitidine [WHO-DD]

Common Name

English

RANITIDINE [HSDB]

Common Name

English

ranitidine [INN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

A02BA02

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

17.1

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

NDF-RT

N0000175784

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

WHO-ATC

A02BA07

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

NDF-RT

N0000000151

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

LIVERTOX

NBK548867

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

WHO-VATC

QA02BA02

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

NCI_THESAURUS

C29702

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

Code System Code Type Description

RXCUI

9143

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

RxNorm

IUPHAR

1234

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

CHEBI

8776

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

EVMPD

SUB10258MIG

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

DAILYMED

884KT10YB7

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

WIKIPEDIA

RANITIDINE

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

PUBCHEM

657345

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

ChEMBL

CHEMBL1790041

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

EPA CompTox

DTXSID8045191

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

LACTMED

Ranitidine

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

NSC

757851

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

DRUG CENTRAL

2358

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

DRUG BANK

DB00863

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

CAS

66357-35-5

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

MESH

D011899

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

FDA UNII

884KT10YB7

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

ECHA (EC/EINECS)

266-332-5

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

MERCK INDEX

m9498

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

Merck Index

HSDB

3925

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

NCI_THESAURUS

C29412

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

INN

4660

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

SMS_ID

100000092215

Created by admin on Fri Dec 15 16:14:18 UTC 2023 , Edited by admin on Fri Dec 15 16:14:18 UTC 2023

PRIMARY

Related Record Type Details


					XC55JSP2CX

HISTAMINE H2 RECEPTOR

TARGET -> INHIBITOR


					7AJ51I17KG

RANITIDINE BISMUTH CITRATE

SALT/SOLVATE -> PARENT

Amount:


					4007E25Z4Z

OCT-3

TRANSPORTER -> INHIBITOR


					BK76465IHM

RANITIDINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					B46KUN2O9L

MATE-2

TRANSPORTER -> INHIBITOR


					482M00274D

OCT-2

TRANSPORTER -> INHIBITOR


					6NP3XSMIP3

MULTIDRUG AND TOXIN EXTRUSION PROTEIN 1

TRANSPORTER -> INHIBITOR


					ONY583280Z

OCT-1

TRANSPORTER -> INHIBITOR


					ONY583280Z

OCT-1

TRANSPORTER -> SUBSTRATE


					22ES734693

MULTIDRUG RESISTANCE PROTEIN 1

TRANSPORTER -> SUBSTRATE

Related Record Type Details


					TK8SB999BQ

RANITIDINE S-OXIDE

METABOLITE INACTIVE -> PARENT

Interaction Type:

MINOR


					K131L1Z4KY

RANITIDINE N-OXIDE

METABOLITE INACTIVE -> PARENT

Amount:


					L0OF19OW3L

DESMETHYLRANITIDINE

METABOLITE INACTIVE -> PARENT


					L0OF19OW3L

DESMETHYLRANITIDINE

METABOLITE INACTIVE -> PARENT

Interaction Type:

MINOR

Qualification:

URINE


					TK8SB999BQ

RANITIDINE S-OXIDE

METABOLITE INACTIVE -> PARENT

Interaction Type:

MINOR

Qualification:

URINE

Amount:

Related Record Type Details


					884KT10YB7

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Route of Elimination	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC				ELDERLY: 3 - 4 HOURS CHILDREN: 1.7 - 2.8 HOURS ADULTS, RENAL IMPAIRMENT: 4.8 - 9.8 HOURS

MAXIMUM TOLERATED DOSE	TOXICITY				NON-ULCER INDIGESTION, PROPHYLAXIS AND TREATMENT: 300 MG/DAY

Volume of Distribution	PHARMACOKINETIC

PROTEIN BINDING	PHARMACOKINETIC