U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C18H19NOS.ClH
Molecular Weight 333.876
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DULOXETINE HYDROCHLORIDE

SMILES

Cl.CNCC[C@H](OC1=C2C=CC=CC2=CC=C1)C3=CC=CS3

InChI

InChIKey=BFFSMCNJSOPUAY-LMOVPXPDSA-N
InChI=1S/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/m0./s1

HIDE SMILES / InChI
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C18H19NOS
Molecular Weight 297.415
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:41:44 UTC 2023
Edited
by admin
on Fri Dec 15 15:41:44 UTC 2023
Record UNII
9044SC542W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DULOXETINE HYDROCHLORIDE
JAN   MART.   MI   ORANGE BOOK   USAN   USP-RS   WHO-DD  
USAN  
Official Name English
DULOXETINE HYDROCHLORIDE [JAN]
Common Name English
DULOXETINE (AS HYDROCHLORIDE)
Common Name English
DULOXETINE LILLY
Systematic Name English
DULOXETINE HYDROCHLORIDE [MART.]
Common Name English
Duloxetine hydrochloride [WHO-DD]
Common Name English
LY-248686 HCL
Code English
CYMBALTA
Brand Name English
(+)-(S)-N-METHYL-.GAMMA.-(1-NAPHTHYLOXY)-2-THIOPHENEPROPYLAMINE HYDROCHLORIDE
Systematic Name English
DULOXETINE HYDROCHLORIDE [EP MONOGRAPH]
Common Name English
LY248686 HCL
Code English
DULOXETINE BOEHRINGER INGELHEIM
Brand Name English
ARICLAIM
Brand Name English
2-THIOPHENEPROPANAMINE, N-METHYL-.GAMMA.-(1-NAPHTHALENYLOXY)-, HYDROCHLORIDE, (S)-
Systematic Name English
DULOXETINE HYDROCHLORIDE [MI]
Common Name English
XERISTAR
Brand Name English
DULOXETINE MYLAN
Brand Name English
DULOXETINE HYDROCHLORIDE [ORANGE BOOK]
Common Name English
DULOXETINE HYDROCHLORIDE [USP MONOGRAPH]
Common Name English
DULOXETINE HCL
Common Name English
DULOXETINE HYDROCHLORIDE [USP-RS]
Common Name English
NSC-759112
Code English
DULOXETINE HYDROCHLORIDE [USAN]
Common Name English
Classification Tree Code System Code
EMA ASSESSMENT REPORTS DULOXETINE MYLAN (AUTHORIZED: DEPRESSIVE DISORDER, MAJOR)
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
EMA ASSESSMENT REPORTS ARICLAIM (AUTHORIZED: DIABETIC NEUROPATHIES)
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
EMA ASSESSMENT REPORTS DULOXETINE MYLAN (AUTHORIZED: DIABETIC NEUROPATHIES)
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
EMA ASSESSMENT REPORTS CYMBALTA (AUTHORIZED: DEPRESSIVE DISORDER, MAJOR)
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
EMA ASSESSMENT REPORTS XERISTAR (AUTHORIZED: DEPRESSIVE DISORDER, MAJOR)
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
EMA ASSESSMENT REPORTS DULOXETINE BOEHRINGER INGELHEIM (WITHDRAWN: DIABETIC NEUROPATHIES)
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
EMA ASSESSMENT REPORTS CYMBALTA (AUTHORIZED: DIABETIC NEUROPATHIES)
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
EMA ASSESSMENT REPORTS DULOXETINE LILLY (AUTHORIZED: DIABETIC NEUROPATHIES)
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
EMA ASSESSMENT REPORTS XERISTAR (AUTHORIZED: DIABETIC NEUROPATHIES)
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
NCI_THESAURUS C265
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
EMA ASSESSMENT REPORTS YENTREVE (AUTHORIZED: URINARY INCONTINENCE, STRESS)
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
Code System Code Type Description
USAN
EE-18
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
NCI_THESAURUS
C65496
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
CHEBI
31526
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
FDA UNII
9044SC542W
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
SMS_ID
100000093366
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
ChEMBL
CHEMBL1175
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
EPA CompTox
DTXSID9046443
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
EVMPD
SUB20026
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
PUBCHEM
60834
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
NSC
759112
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
CAS
136434-34-9
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
DAILYMED
9044SC542W
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
RS_ITEM_NUM
1229817
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
RXCUI
476250
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY RxNorm
DRUG BANK
DB00476
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY
MERCK INDEX
m4782
Created by admin on Fri Dec 15 15:41:44 UTC 2023 , Edited by admin on Fri Dec 15 15:41:44 UTC 2023
PRIMARY Merck Index
Related Record Type Details
Structure of DULOXETINE HYDROCHLORIDE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
EP
Structure of DULOXETINE
PARENT -> SALT/SOLVATE
Structure of DULOXETINE HYDROCHLORIDE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Related Record Type Details
Structure of PARA-NAPHTHOL DULOXETINE
IMPURITY -> PARENT
Structure of DULOXETINE HYDROCHLORIDE, (R)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of (3S)-N-METHYL-3-(NAPHTHALEN-1-YLOXY)-3-(THIOPHEN-3-YL)PROPAN-1-AMINE
IMPURITY -> PARENT
ASSAY (HPLC)
USP
Structure of DULOXETINE, (R)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of DULOXETINE
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966