DOXAPRAM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C24H30N2O2
Molecular Weight	378.5072
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DOXAPRAM

Structure Search

SMILES

CCN1CC(CCN2CCOCC2)C(C1=O)(C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChIKey=XFDJYSQDBULQSI-UHFFFAOYSA-N

InChI=1S/C24H30N2O2/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12,22H,2,13-19H2,1H3

HIDE SMILES / InChI

Molecular Formula	C24H30N2O2
Molecular Weight	378.5072
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 14:58:29 UTC 2023` Edited by `admin` on `Fri Dec 15 14:58:29 UTC 2023`
Record UNII	94F3830Q73
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DOXAPRAM

Official Name

English

DOXAPRAM [HSDB]

Common Name

English

DOCATONE

Brand Name

English

(±)-1-ETHYL-4-(2-MORPHOLINOETHYL)-3,3-DIPHENYL-2-PYRROLIDINONE

Systematic Name

English

DOXAPRAM [MI]

Common Name

English

DOXAPRAM [VANDF]

Common Name

English

2-PYRROLIDINONE, 1-ETHYL-4-(2-(4-MORPHOLINYL)ETHYL)-3,3-DIPHENYL-

Systematic Name

English

doxapram [INN]

Common Name

English

Doxapram [WHO-DD]

Common Name

English

1-ETHYL-4-(2-(4-MORPHOLINYL)ETHYL)-3,3-DIPHENYL-2-PYRROLIDINONE

Systematic Name

English

2-PYRROLIDINONE, 1-ETHYL-4-(2-(4-MORPHOLINYL)ETHYL)-3,3-DIPHENYL-, (±)-

Systematic Name

English

1-ETHYL-4-(2-MORPHOLINOETHYL)-3,3-DIPHENYL-2-PYRROLIDINONE

Systematic Name

English

DOXAPRAM [JAN]

Common Name

English

2-PYRROLIDINONE, 1-ETHYL-4-(2-MORPHOLINOETHYL)-3,3-DIPHENYL-

Systematic Name

English

Classification Tree Code System Code

WHO-ATC

R07AB01

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

NDF-RT

N0000009393

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

WHO-VATC

QR07AB01

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

CFR

21 CFR 522.775

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

NCI_THESAURUS

C47795

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

NDF-RT

N0000175716

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

Code System Code Type Description

MERCK INDEX

m4751

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

Merck Index

CAS

162521-37-1

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

SUPERSEDED

HSDB

3318

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

DAILYMED

94F3830Q73

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

DRUG BANK

DB00561

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

SMS_ID

100000080771

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

CHEBI

681848

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

ChEMBL

CHEMBL1754

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

NCI_THESAURUS

C61736

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

IUPHAR

7169

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

RXCUI

3637

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

RxNorm

INN

1462

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

EVMPD

SUB06382MIG

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

PUBCHEM

3156

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

WIKIPEDIA

DOXAPRAM

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

EPA CompTox

DTXSID2022963

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

FDA UNII

94F3830Q73

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

CAS

309-29-5

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

MESH

D004315

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

DRUG CENTRAL

953

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

ECHA (EC/EINECS)

206-216-3

Created by admin on Fri Dec 15 14:58:29 UTC 2023 , Edited by admin on Fri Dec 15 14:58:29 UTC 2023

PRIMARY

Related Record Type Details


					8J865SG1AT

ENANTIOMER -> RACEMATE


					FB8713U6DM

DOXAPRAM HYDROCHLORIDE ANHYDROUS

SALT/SOLVATE -> PARENT


					9186ARG44D

ENANTIOMER -> RACEMATE


					P5RU6UOQ5Y

DOXAPRAM HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					73P6569O4H

1-ETHYL-4-(2-((2-HYDROXYETHYL)AMINO)ETHYL)-3,3-DIPHENYLPYRROLIDIN-2-ONE

METABOLITE -> PARENT

Comments:

In a premature newborn following an intravenous infusion of doxapram.

Qualification:

URINE


					7SY5VUG7T7

AHR-5955

METABOLITE -> PARENT

Amount:


					9X29GQN4HV

N2-MONODESMETHYLNIZATIDINE

METABOLITE -> PARENT

Interaction Type:

MAJOR

Qualification:

PLASMA


					8893TQB54V

AHR-5904

METABOLITE -> PARENT

Comments:

In a premature newborn following an intravenous infusion of doxapram.

Qualification:

URINE

Related Record Type Details


					94F3830Q73

DOXAPRAM

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC