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Details

Stereochemistry ACHIRAL
Molecular Formula C12H18N2O3S
Molecular Weight 270.348
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TOLBUTAMIDE

SMILES

CCCCNC(=O)NS(=O)(=O)C1=CC=C(C)C=C1

InChI

InChIKey=JLRGJRBPOGGCBT-UHFFFAOYSA-N
InChI=1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)

HIDE SMILES / InChI
Molecular Formula C12H18N2O3S
Molecular Weight 270.348
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 15:47:22 UTC 2023
Edited
by admin
on Sat Dec 16 15:47:22 UTC 2023
Record UNII
982XCM1FOI
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TOLBUTAMIDE
EP   HSDB   INN   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
INN  
Official Name English
TOLBUTAMIDE [VANDF]
Common Name English
BUTAMIDE
Common Name English
TOLBUTAMIDE [EP MONOGRAPH]
Common Name English
tolbutamide [INN]
Common Name English
1-BUTYL-3-(P-TOLYLSULFONYL)UREA
Common Name English
BENZENESULFONAMIDE, N-((BUTYLAMINO)CARBONYL)-4-METHYL-
Systematic Name English
TOLBUTAMIDE [MART.]
Common Name English
Tolbutamide [WHO-DD]
Common Name English
TOLBUTAMIDUM [WHO-IP LATIN]
Common Name English
NSC-23813
Code English
ORINASE
Common Name English
NSC-87833
Code English
TOLBUTAMIDE [MI]
Common Name English
ARKOZAL
Common Name English
TOLBUTAMIDE [HSDB]
Common Name English
GLYCONON
Common Name English
TOLBUTAMIDE [USP MONOGRAPH]
Common Name English
DIABETAMID
Common Name English
TOLBUTAMIDE [WHO-IP]
Common Name English
TOLBUTAMIDE [JAN]
Common Name English
IPOGLICONE
Common Name English
WILLBUTAMIDE
Common Name English
TOLBUTAMIDE [USP-RS]
Common Name English
TOLBUTAMIDE [ORANGE BOOK]
Common Name English
Classification Tree Code System Code
CFR 21 CFR 310.517
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
WHO-VATC QA10BB03
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
LIVERTOX 976
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
NDF-RT N0000008054
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
WHO-VATC QV04CA01
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
WHO-ATC A10BB03
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
WHO-ATC V04CA01
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
NDF-RT N0000175608
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
NDF-RT N0000008054
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
NDF-RT N0000008054
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
NCI_THESAURUS C97936
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
Code System Code Type Description
PUBCHEM
5505
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-594-3
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
MESH
D014044
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
CHEBI
27999
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
IUPHAR
6848
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
WIKIPEDIA
TOLBUTAMIDE
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
HSDB
3393
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
SMS_ID
100000091980
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
MERCK INDEX
m10937
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY Merck Index
FDA UNII
982XCM1FOI
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
ChEMBL
CHEMBL782
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
EVMPD
SUB11150MIG
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
LACTMED
Tolbutamide
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
NSC
87833
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
TOLBUTAMIDE
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY Description: A white or almost white, crystalline powder; odourless or almost odourless. Solubility: Practically insoluble in water; soluble in 10 parts of ethanol (~750 g/l) TS; soluble in acetone R. Category: Antidiabetic. Storage: Tolbutamide should be kept in a tightly closed container, protected from light. Additional information: Even in the absence of light, Tolbutamide is gradually degraded on exposure to a humid atmosphere, the decomposition being faster at higher temperatures. Definition: Tolbutamide contains not less than 99.0% and not more than 101.0% of C12H18N2O3S, calculated with reference to the dried substance.
NSC
23813
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
INN
602
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
DRUG CENTRAL
2696
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
EPA CompTox
DTXSID8021359
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
RS_ITEM_NUM
1670003
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
RXCUI
10635
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY RxNorm
NCI_THESAURUS
C66610
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
DRUG BANK
DB01124
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
CAS
64-77-7
Created by admin on Sat Dec 16 15:47:23 UTC 2023 , Edited by admin on Sat Dec 16 15:47:23 UTC 2023
PRIMARY
Related Record Type Details
CYTOCHROME P450 2C9
METABOLIC ENZYME -> SUBSTRATE
Structure of TOLBUTAMIDE SODIUM
SALT/SOLVATE -> PARENT
ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8
TARGET -> INHIBITOR
Related Record Type Details
Structure of 4-CARBOXY TOLBUTAMIDE
METABOLITE INACTIVE -> PARENT
MAJOR
URINE
Structure of HYDROXYMETHYLTOLBUTAMIDE
METABOLITE INACTIVE -> PARENT
MINOR
URINE
Related Record Type Details
Structure of 4-TOLYLSULFONYLUREA
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of P-TOLUENESULFONAMIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of TOLAZAMIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of TOLBUTAMIDE
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