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Details

Stereochemistry ACHIRAL
Molecular Formula C12H19N2O2.CH3O4S
Molecular Weight 334.389
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NEOSTIGMINE METHYLSULFATE

SMILES

COS([O-])(=O)=O.CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C

InChI

InChIKey=OSZNNLWOYWAHSS-UHFFFAOYSA-M
InChI=1S/C12H19N2O2.CH4O4S/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;1-5-6(2,3)4/h6-9H,1-5H3;1H3,(H,2,3,4)/q+1;/p-1

HIDE SMILES / InChI
Molecular Formula C12H19N2O2
Molecular Weight 223.2915
Charge 1
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula CH3O4S
Molecular Weight 111.097
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:14:47 UTC 2023
Edited
by admin
on Fri Dec 15 16:14:47 UTC 2023
Record UNII
98IMH7M386
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NEOSTIGMINE METHYLSULFATE
GREEN BOOK   ORANGE BOOK   USP   USP-RS   VANDF  
Common Name English
NEOSTIGMINE METHYLSULFATE [USP-RS]
Common Name English
NEOSTIGMINE METILSULFATE [WHO-IP]
Common Name English
NSC-93753
Code English
BENZENAMINIUM, 3-(((DIMETHYLAMINO)CARBONYL)OXY)-N,N,N-TRIMETHYL-, METHYL SULFATE
Common Name English
INTRASTIGMINA
Common Name English
NEOSTIGMINE METHYLSULFATE [GREEN BOOK]
Common Name English
NEOSTIGMINE METILSULFATE [MART.]
Common Name English
(M-HYDROXYPHENYL)TRIMETHYLAMMONIUM METHYL SULPHATE DIMETHYLCARBAMATE
Systematic Name English
Neostigmine metilsulfate [WHO-DD]
Common Name English
NEOSTIGMINE METILSULFATE
EP   MART.   WHO-DD   WHO-IP  
Common Name English
NEOSTIGMINI METILSULFAS [WHO-IP LATIN]
Common Name English
NEOSTIGMINE METHYLSULFATE [JAN]
Common Name English
NEOSTIGMINE METILSULFATE [EP MONOGRAPH]
Common Name English
NEOSTIGMINE METHYLSULFATE [USP IMPURITY]
Common Name English
SYNTOSTIGMIN
Common Name English
PREVDUO COMPONENT NEOSTIGMINE METHYLSULFATE
Brand Name English
NEOSTIGMINE METHYLSULFATE COMPONENT OF PREVDUO
Brand Name English
NEOSTIGMINE METHYLSULFATE [USP MONOGRAPH]
Common Name English
BENZENAMINIUM, 3-(((DIMETHYLAMINO)CARBONYL)OXY)-N,N,N-TRIMETHYL-, METHYL SULPHATE
Common Name English
NEOSTIGMINE METHYLSULPHATE
Common Name English
(M-HYDROXYPHENYL)TRIMETHYLAMMONIUM METHYL SULFATE DIMETHYLCARBAMATE
Systematic Name English
NEOSTIGMINE METHYLSULFATE [VANDF]
Common Name English
NEOSTIGMINE METHYLSULFATE [ORANGE BOOK]
Common Name English
NEOSTIGMINE METHYL SULFATE [MI]
Common Name English
Classification Tree Code System Code
CFR 21 CFR 522.1503
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
FDA ORPHAN DRUG 359611
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
NCI_THESAURUS C47792
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
Code System Code Type Description
DAILYMED
98IMH7M386
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
NCI_THESAURUS
C76613
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
FDA UNII
98IMH7M386
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
RS_ITEM_NUM
1460000
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
CAS
51-60-5
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-109-5
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
SMS_ID
100000086473
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
EVMPD
SUB20700
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
DRUG BANK
DBSALT000128
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
MERCK INDEX
m7819
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY Merck Index
ChEMBL
CHEMBL278020
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
NEOSTIGMINE METHYLSULFATE
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY Description: A white, crystalline powder; odourless. Solubility: Very soluble in water; freely soluble in ethanol (~750 g/l) TS. Category: Cholinergic. Storage: Neostigmine metilsulfate should be kept in a tightly closed container, protected from light. Definition: Neostigmine metilsulfate contains not less than 98.0% and not more than 100.5% of C13H22N2O6S, calculated with reference to the dried substance.
NSC
93753
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
RXCUI
7316
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY RxNorm
EPA CompTox
DTXSID40199003
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
PUBCHEM
5824
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
CHEBI
7514
Created by admin on Fri Dec 15 16:14:47 UTC 2023 , Edited by admin on Fri Dec 15 16:14:47 UTC 2023
PRIMARY
Related Record Type Details
Structure of METHYL SULFATE
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Structure of NEOSTIGMINE
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Structure of NEOSTIGMINE METHYLSULFATE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
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Structure of NEOSTIGMINE METHYLSULFATE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
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Structure of 3-(DIMETHYLAMINO)PHENOL
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CHROMATOGRAPHIC PURITY (HPLC/UV)
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Structure of 3-HYDROXY-N,N,N-TRIMETHYLBENZENAMINIUM
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
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Structure of NORNEOSTIGMINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
Structure of NEOSTIGMINE
ACTIVE MOIETY
NIH
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