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Details

Stereochemistry ABSOLUTE
Molecular Formula C18H25NO.BrH.H2O
Molecular Weight 370.324
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEXTROMETHORPHAN HYDROBROMIDE

SMILES

O.Br.[H][C@]12CCCC[C@]13CCN(C)[C@H]2CC4=CC=C(OC)C=C34

InChI

InChIKey=STTADZBLEUMJRG-IKNOHUQMSA-N
InChI=1S/C18H25NO.BrH.H2O/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H;1H2/t15-,17+,18+;;/m1../s1

HIDE SMILES / InChI
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C18H25NO
Molecular Weight 271.3972
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula BrH
Molecular Weight 80.912
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:04:42 UTC 2023
Edited
by admin
on Fri Dec 15 15:04:42 UTC 2023
Record UNII
9D2RTI9KYH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEXTROMETHORPHAN HYDROBROMIDE
EP   ORANGE BOOK   USP   USP-RS   VANDF   WHO-IP  
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE COMPONENT OF MUCINEX DM
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE COMPONENT OF NUEDEXTA
Common Name English
BROMFED-DM COMPONENT DEXTROMETHORPHAN HYDROBROMIDE
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE [USP-RS]
Common Name English
ST. JOSEPH COUGH SYRUP
Brand Name English
AZEDIPAMIN
Common Name English
AUVELITY COMPONENT DEXTROMETHORPHAN HYDROBROMIDE
Brand Name English
DEXTROMETHORPHAN HYDROBROMIDE COMPONENT OF BROMANATE DM
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE HYDRATE [JAN]
Common Name English
BROMANATE DM COMPONENT DEXTROMETHORPHAN HYDROBROMIDE
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE COMPONENT OF PHERAZINE DM
Common Name English
DIMETANE-DX COMPONENT DEXTROMETHORPHAN HYDROBROMIDE
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE HYDRATE
JAN  
Common Name English
AVP-923 COMPONENT DEXTROMETHORPHAN HYDROBROMIDE
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE [EP MONOGRAPH]
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE COMPONENT OF AUVELITY
Brand Name English
DEXTROMETHORPHAN HYDROBROMIDE [WHO-IP]
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE MONOHYDRATE
WHO-DD  
Common Name English
3-METHOXY-17-METHYL-9.ALPHA.,13.ALPHA.,14.ALPHA.-MORPHINAN HBR MONOHYDRATE
Common Name English
MORPHINAN, 3-METHOXY-17-METHYL-, (9.ALPHA.,13.ALPHA.,14.ALPHA.)-, HBR, MONOHYDRATE
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE COMPONENT OF BROMFED-DM
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE COMPONENT OF DIMETANE-DX
Common Name English
MORPHINAN, 3-METHOXY-17-METHYL-, (9.ALPHA.,13.ALPHA.,14.ALPHA.)-, HYDROBROMIDE, MONOHYDRATE
Common Name English
CALMOCITENE
Common Name English
DRIXORAL COUGH
Common Name English
DEXTROMETHORPHANI HYDROBROMIDUM [WHO-IP]
Common Name English
SIMASEDAN
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE OROS TABLETS
Common Name English
DEXTROMETHORPHAN HBR
Common Name English
MUCINEX DM COMPONENT DEXTROMETHORPHAN HYDROBROMIDE
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE COMPONENT OF PROMETHAZINE DM
Common Name English
NUEDEXTA COMPONENT DEXTROMETHORPHAN HYDROBROMIDE
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE [ORANGE BOOK]
Common Name English
BENYLIN DM
Common Name English
Dextromethorphan hydrobromide monohydrate [WHO-DD]
Common Name English
3-Methoxy-17-methyl-9α,13α,14α-morphinan hydrobromide monohydrate
Common Name English
DEXTROMETHORPHAN HYDROBROMIDE [VANDF]
Common Name English
PROMETHAZINE DM COMPONENT DEXTROMETHORPHAN HYDROBROMIDE
Common Name English
NUEDEXTA
Brand Name English
DEXTROMETHORPHAN HYDROBROMIDE [USP MONOGRAPH]
Common Name English
ROMILAR
Common Name English
PEDIACARE 1
Common Name English
PHERAZINE DM COMPONENT DEXTROMETHORPHAN HYDROBROMIDE
Common Name English
Classification Tree Code System Code
CFR 21 CFR 341.14
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
FDA ORPHAN DRUG 556716
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
NCI_THESAURUS C67413
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
EMA ASSESSMENT REPORTS NUEDEXTA (AUTHORIZED: NEUROBEHAVIORAL MANIFESTATIONS)
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
NCI_THESAURUS C1506
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
CFR 21 CFR 341.74
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
Code System Code Type Description
CHEBI
4470
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
DAILYMED
9D2RTI9KYH
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
DRUG BANK
DBSALT000376
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
DEXTROMETHORPHAN HYDROBROMIDE
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY Description: A white or almost white, crystalline powder.Solubility: Sparingly soluble in water; freely soluble in ethanol (~750 g/L) TS.Category: Antitussive.Storage: Dextromethorphan hydrobromide should be kept in a well-closed container.
RXCUI
102490
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY RxNorm
RS_ITEM_NUM
1181007
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
FDA UNII
9D2RTI9KYH
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
EVMPD
SUB01645MIG
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
ChEMBL
CHEMBL52440
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
NCI_THESAURUS
C423
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
EVMPD
SUB27099
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
WIKIPEDIA
Dextromethorphan hydrobromide
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
EPA CompTox
DTXSID8045569
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
CAS
6700-34-1
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
PUBCHEM
5462351
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
CHEBI
4471
Created by admin on Fri Dec 15 15:04:42 UTC 2023 , Edited by admin on Fri Dec 15 15:04:42 UTC 2023
PRIMARY
Related Record Type Details
Structure of Dextromethorphan
PARENT -> SALT/SOLVATE
Structure of DEXTROMETHORPHAN HYDROBROMIDE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
EP
Structure of DEXTROMETHORPHAN HYDROBROMIDE ANHYDROUS
ANHYDROUS->SOLVATE
Structure of DEXTROMETHORPHAN HYDROBROMIDE
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
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Structure of ENT-3-METHOXYMORPHINAN
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Structure of DEXTRORPHAN
IMPURITY -> PARENT
and not more than 1 such peak has an area greater than 0.5 times the area of the principal peak in the chromatogram obtained with reference solution (b) (0.25 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of LEVOMETHORPHAN
IMPURITY -> PARENT
Structure of ENT-3-METHOXY-17-METHYLMORPHINAN-10-ONE
IMPURITY -> PARENT
and not more than 1 such peak has an area greater than 0.5 times the area of the principal peak in the chromatogram obtained with reference solution (b) (0.25 per cent); For the calculation of contents, multiply the peak areas by 0.2
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DEXTROMETHORPHAN N-OXIDE
IMPURITY -> PARENT
Related Record Type Details
Structure of Dextromethorphan
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