CAPTOPRIL

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H15NO3S
Molecular Weight	217.285
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CAPTOPRIL

Structure Search

SMILES

C[C@H](CS)C(=O)N1CCC[C@H]1C(O)=O

InChI

InChIKey=FAKRSMQSSFJEIM-RQJHMYQMSA-N

InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C9H15NO3S
Molecular Weight	217.285
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:23:49 UTC 2023` Edited by `admin` on `Fri Dec 15 15:23:49 UTC 2023`
Record UNII	9G64RSX1XD
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CAPTOPRIL

Official Name

English

CAPOTEN

Brand Name

English

CAPTOPRIL [WHO-IP]

Common Name

English

CAPTOPRIL [MART.]

Common Name

English

CAPTOPRIL [USP MONOGRAPH]

Common Name

English

Captopril [WHO-DD]

Common Name

English

SA-333

Code

English

GARRANIL

Common Name

English

1-((2S)-3-MERCAPTO-2-METHYLPROPIONYL)-L-PROLINE

Systematic Name

English

SQ-14225

Code

English

TENSIOMIN

Common Name

English

CAPTOMAX

Common Name

English

CAPTOPRIL [USP-RS]

Common Name

English

SQ -14225

Code

English

CAPTOPRIL [USAN]

Common Name

English

CAPTOPRIL [HSDB]

Common Name

English

CAPTOPRILUM [WHO-IP LATIN]

Common Name

English

C09AA01

Code

English

FARCOPRIL

Common Name

English

CAPTOPRIL [EP MONOGRAPH]

Common Name

English

CAPTOPRIL [MI]

Common Name

English

L-PROLINE, 1-((2S)-3-MERCAPTO-2-METHYL-1-OXOPROPYL)-

Systematic Name

English

ZAPTO

Common Name

English

APOPRIL

Brand Name

English

MEPHA

Common Name

English

CAPTOPRIL [USP IMPURITY]

Common Name

English

CAPTOPRIL [VANDF]

Common Name

English

CAPTOPRIL [ORANGE BOOK]

Common Name

English

NSC-757419

Code

English

CAPTOPRIL [JAN]

Common Name

English

HYPOPRESS

Common Name

English

captopril [INN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

C09AA01

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

WHO-ATC

C09BA01

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

NDF-RT

N0000000181

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

NDF-RT

N0000175562

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

WHO-VATC

QC09AA01

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

WHO-VATC

QC09BA01

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

NCI_THESAURUS

C247

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

LIVERTOX

NBK548504

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

Code System Code Type Description

MESH

D002216

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

CHEBI

3380

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

NCI_THESAURUS

C340

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

RXCUI

1998

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

RxNorm

ECHA (EC/EINECS)

263-607-1

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

MERCK INDEX

m3046

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

Merck Index

INN

4373

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

ChEMBL

CHEMBL1560

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

WIKIPEDIA

CAPTOPRIL

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

DAILYMED

9G64RSX1XD

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

SMS_ID

100000092557

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

IUPHAR

5158

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

DRUG CENTRAL

484

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

WHO INTERNATIONAL PHARMACOPEIA

CAPTOPRIL

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

Description: A white or almost white, crystalline powder. Solubility: Freely soluble in water, dichloromethane R, and methanol R. Category: Cardiovascular agent; angiotensin-converting enzyme inhibitor. Storage: Captopril should be kept in a tightly closed container, protected from light. Additional information: Captopril may exist in different polymorphic forms. Requirement: Captopril contains not less than 98.0% and not more than 102.0% of C9H15NO3S, calculated with reference to the dried substance.

NSC

757419

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

EVMPD

SUB06081MIG

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

HSDB

6527

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

FDA UNII

9G64RSX1XD

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

DRUG BANK

DB01197

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

RS_ITEM_NUM

1091200

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

CAS

62571-86-2

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

EPA CompTox

DTXSID1037197

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

PUBCHEM

44093

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

LACTMED

Captopril

Created by admin on Fri Dec 15 15:23:49 UTC 2023 , Edited by admin on Fri Dec 15 15:23:49 UTC 2023

PRIMARY

Related Record Type Details


					9G64RSX1XD

CAPTOPRIL

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

EP

Amount:


					91L39G324W

PEPT-2

TRANSPORTER -> SUBSTRATE


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					51FM2R4Y24

ANGIOTENSIN-CONVERTING ENZYME

TARGET -> INHIBITOR

Comments:

Binding Assay

Qualification:

IC50

Amount:


					22ES734693

MULTIDRUG RESISTANCE PROTEIN 1

TRANSPORTER -> INHIBITOR

Amount:


					51FM2R4Y24

ANGIOTENSIN-CONVERTING ENZYME

TARGET -> INHIBITOR


					XYD5147M6H

PEPT-1

TRANSPORTER -> SUBSTRATE


					9G64RSX1XD

CAPTOPRIL

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

USP

Amount:

Related Record Type Details


					1036F0RZ9O

CAPTOPRIL-L-CYSTEINE

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

URINE

Related Record Type Details


					07304AI75I

3-BROMO-2-METHYLPROPIONIC ACID

IMPURITY -> PARENT


					27JC6R80S1

ISOBUTYRYLPROLINE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					V3E4016VAS

3-MERCAPTO-2-METHYLPROPIONIC ACID

IMPURITY -> PARENT


					V3E4016VAS

3-MERCAPTO-2-METHYLPROPIONIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					6HCR5N6952

CAPTOPRIL BROMO ANALOG

IMPURITY -> PARENT


					6HCR5N6952

CAPTOPRIL BROMO ANALOG

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					07304AI75I

3-BROMO-2-METHYLPROPIONIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					PPW0ENH1HA

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					Y139M16FXG

S-ACETYLCAPTOPRIL

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					Y21D2C2453

CAPTOPRIL DISULFIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					27JC6R80S1

ISOBUTYRYLPROLINE

IMPURITY -> PARENT

Related Record Type Details


					9G64RSX1XD

CAPTOPRIL

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC