TRAMADOL HYDROCHLORIDE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C16H25NO2.ClH
Molecular Weight	299.836
Optical Activity	( + / - )
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TRAMADOL HYDROCHLORIDE

Structure Search

SMILES

Cl.COC1=CC=CC(=C1)[C@@]2(O)CCCC[C@@H]2CN(C)C

InChI

InChIKey=PPKXEPBICJTCRU-XMZRARIVSA-N

InChI=1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C16H25NO2
Molecular Weight	263.3752
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:11:40 UTC 2023` Edited by `admin` on `Fri Dec 15 15:11:40 UTC 2023`
Record UNII	9N7R477WCK
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRAMADOL HYDROCHLORIDE

Official Name

English

ZERTANE

Brand Name

English

TRAMADOL HYDROCHLORIDE [VANDF]

Common Name

English

ULTRAM

Brand Name

English

CG-315

Code

English

TRADONAL

Brand Name

English

TRAMADOL HYDROCHLORIDE [MART.]

Common Name

English

NSC-759105

Code

English

TRAMADOL HYDROCHLORIDE CIV

Common Name

English

TRAMADOL HCL

Common Name

English

CONTRAMAL

Brand Name

English

(±)-CIS-2-((DIMETHYLAMINO)METHYL)-1-(M-METHOXYPHENYL)CYCLOHEXANOL HYDROCHLORIDE

Common Name

English

TRAMADOL HYDROCHLORIDE [USAN]

Common Name

English

TRAMADOL HYDROCHLORIDE CIV [USP-RS]

Common Name

English

TRAMADOL HYDROCHLORIDE [JAN]

Common Name

English

CONZIP

Brand Name

English

TRAMADOL HYDROCHLORIDE [USP MONOGRAPH]

Common Name

English

TRAMADOL HYDROCHLORIDE [EP MONOGRAPH]

Common Name

English

NIH-10969

Code

English

ULTRACET COMPONENT TRAMADOL HYDROCHLORIDE

Common Name

English

TRAMADOL HYDROCHLORIDE [MI]

Common Name

English

ZYDOL

Brand Name

English

AMADOL

Brand Name

English

U-26,225A

Code

English

U-26225A

Code

English

TRAMADOL HYDROCHLORIDE [HSDB]

Common Name

English

ZAMUDOL

Brand Name

English

QDOLO

Brand Name

English

TRAMAL

Brand Name

English

Tramadol hydrochloride [WHO-DD]

Common Name

English

TRAMADOL HYDROCHLORIDE COMPONENT OF ULTRACET

Common Name

English

TRAMADOL HYDROCHLORIDE [ORANGE BOOK]

Common Name

English

CYCLOHEXANOL, 2-((DIMETHYLAMINO)METHYL)-1-(3-METHOXYPHENYL)-, HYDROCHLORIDE, (1R,2R)-REL-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C241

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

DEA NO.

9278

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

EU-Orphan Drug

Tramadol hydrochloride

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

FDA ORPHAN DRUG

192804

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

FDA ORPHAN DRUG

197004

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

Code System Code Type Description

MERCK INDEX

m10996

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

Merck Index

SMS_ID

100000093275

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

ChEMBL

CHEMBL1237044

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

NCI_THESAURUS

C29508

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

CAS

53611-16-8

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

SUPERSEDED

EVMPD

SUB04927MIG

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

CHEBI

9648

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

DRUG BANK

DBSALT000181

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

DAILYMED

9N7R477WCK

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

PUBCHEM

63013

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

RXCUI

82110

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

RxNorm

CAS

194602-08-9

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

SUPERSEDED

CAS

2914-78-5

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

NON-SPECIFIC STEREOCHEMISTRY

CHEBI

32250

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

CAS

22204-88-2

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

SUPERSEDED

CAS

36282-47-0

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

ECHA (EC/EINECS)

252-950-2

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

FDA UNII

9N7R477WCK

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

RS_ITEM_NUM

1672600

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

NSC

759105

Created by admin on Fri Dec 15 15:11:40 UTC 2023 , Edited by admin on Fri Dec 15 15:11:40 UTC 2023

PRIMARY

Related Record Type Details


					9N7R477WCK

TRAMADOL HYDROCHLORIDE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

EP

Amount:


					39J1LGJ30J

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PARENT -> SALT/SOLVATE


					9N7R477WCK

TRAMADOL HYDROCHLORIDE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

USP

Amount:

Related Record Type Details


					0X71A1UR01

1,2-DEHYDRO TRAMADOL

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EP


					2WA8F50C3F

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Comments:

UNSPECIFIED

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					7AO28L53FN

TRAMADOL, TRANS-

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP


					7AO28L53FN

TRAMADOL, TRANS-

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					2K361MJ2WZ

2-((DIMETHYLAMINO)METHYL)CYCLOHEXANONE

IMPURITY -> PARENT

Comments:

TLC, ASSUMED FREE BASE

Interaction Type:

CHROMATOGRAPHIC PURITY (TLC)

Qualification:

USP

Amount:


					2K361MJ2WZ

2-((DIMETHYLAMINO)METHYL)CYCLOHEXANONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (TLC)

Qualification:

EP

Amount:

Related Record Type Details


					39J1LGJ30J

TRAMADOL

ACTIVE MOIETY