OFLOXACIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C18H20FN3O4
Molecular Weight	361.3675
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of OFLOXACIN

Structure Search

SMILES

CC1COC2=C3N1C=C(C(O)=O)C(=O)C3=CC(F)=C2N4CCN(C)CC4

InChI

InChIKey=GSDSWSVVBLHKDQ-UHFFFAOYSA-N

InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)

HIDE SMILES / InChI

Molecular Formula	C18H20FN3O4
Molecular Weight	361.3675
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:35:52 UTC 2023` Edited by `admin` on `Fri Dec 15 18:35:52 UTC 2023`
Record UNII	A4P49JAZ9H
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

OFLOXACIN

Official Name

English

NSC-758178

Code

English

OFLOXACIN [EP MONOGRAPH]

Common Name

English

HOE-280

Code

English

FLOXIN

Brand Name

English

9-FLUORO-2,3-DIHYDRO-3-METHYL-10-(4-METHYL-1-PIPERAZINYL)-7-OXO-7H-PYRIDO(1,2,3-DE)(1,4)BENZOXAZINE-6-CARBOXYLIC ACID, DL-

Common Name

English

OFLOXACIN [MART.]

Common Name

English

7H-PYRIDO(1,2,3-DE)-1,4-BENZOXAZINE-6-CARBOXYLIC ACID, 9-FLUORO-2,3-DIHYDRO-3-METHYL-10-(4-METHYL-1-PIPERAZINYL)-7-OXO-, (±)-

Common Name

English

Ofloxacin [WHO-DD]

Common Name

English

OFLOXACIN [ORANGE BOOK]

Common Name

English

OFLOXACIN [JAN]

Common Name

English

J01MA01

Code

English

OFLOXACIN [VANDF]

Common Name

English

OFLOXACIN [USP-RS]

Common Name

English

OFLOXACIN [USAN]

Common Name

English

HOE 280

Code

English

OCUFLOX

Brand Name

English

ofloxacin [INN]

Common Name

English

DL-8280

Code

English

OFLOXACIN [USP MONOGRAPH]

Common Name

English

OFLOXACIN [MI]

Common Name

English

NSC-727071

Code

English

Classification Tree Code System Code

WHO-ATC

J01MA01

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

WHO-ATC

J01RA09

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

NCI_THESAURUS

C795

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

WHO-VATC

QS01AE01

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

NDF-RT

N0000007606

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

WHO-ATC

S01AX11

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

LIVERTOX

NBK548923

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

NDF-RT

N0000175937

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

WHO-ESSENTIAL MEDICINES LIST

6.2.4

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

WHO-VATC

QS02AA16

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

FDA ORPHAN DRUG

56791

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

WHO-ATC

S02AA16

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

WHO-ATC

S01AE01

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

WHO-VATC

QJ01MA01

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

Code System Code Type Description

CAS

82419-36-1

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

DRUG BANK

DB01165

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

NSC

758178

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

RS_ITEM_NUM

1478108

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

NSC

727071

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

USAN

W-70

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

FDA UNII

A4P49JAZ9H

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

EPA CompTox

DTXSID3041085

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

DAILYMED

A4P49JAZ9H

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

MERCK INDEX

m8133

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

Merck Index

LACTMED

Ofloxacin

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

ChEMBL

CHEMBL4

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

SMS_ID

100000092309

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

WIKIPEDIA

OFLOXACIN

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

RXCUI

7623

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

RxNorm

DRUG CENTRAL

1981

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

INN

5322

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

HSDB

8030

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

MESH

D015242

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

EVMPD

SUB09422MIG

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

NCI_THESAURUS

C712

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

CHEBI

7731

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

PUBCHEM

4583

Created by admin on Fri Dec 15 18:35:52 UTC 2023 , Edited by admin on Fri Dec 15 18:35:52 UTC 2023

PRIMARY

Related Record Type Details


					A4P49JAZ9H

OFLOXACIN

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

USP

Amount:


					I2UWV315WA

OFLOXACIN HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					A4P49JAZ9H

OFLOXACIN

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

EP

Amount:

Related Record Type Details


					5S4363I4ED

N-DESMETHYL OFLOXACIN

METABOLITE -> PARENT

Qualification:

URINE

Amount:


					2400MFQ95B

OFLOXACIN N-OXIDE

METABOLITE -> PARENT

Qualification:

URINE

Amount:


					2400MFQ95B

OFLOXACIN N-OXIDE

METABOLITE -> PARENT

Qualification:

FECAL

Amount:


					5S4363I4ED

N-DESMETHYL OFLOXACIN

METABOLITE -> PARENT

Qualification:

FECAL

Amount:

Related Record Type Details


					2400MFQ95B

OFLOXACIN N-OXIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					8L87OH5G1Z

9-PIPERAZINO OFLOXACIN

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					Q12TEZ182A

DECARBOXYL OFLOXACIN

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					4Q53R99NFD

DEFLUOROOFLOXACIN

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					501W86694Z

OFLOXACIN Q ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (TLC)

Qualification:

EP

Amount:


					5S4363I4ED

N-DESMETHYL OFLOXACIN

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					A4P49JAZ9H

OFLOXACIN

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Tmax	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC