BEXAROTENE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H28O2
Molecular Weight	348.4779
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BEXAROTENE

Structure Search

SMILES

CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(O)=O)C(C)(C)CCC2(C)C

InChI

InChIKey=NAVMQTYZDKMPEU-UHFFFAOYSA-N

InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)

HIDE SMILES / InChI

Molecular Formula	C24H28O2
Molecular Weight	348.4779
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:34:54 UTC 2023` Edited by `admin` on `Fri Dec 15 15:34:54 UTC 2023`
Record UNII	A61RXM4375
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BEXAROTENE

Official Name

English

BEXAROTENE [EMA EPAR]

Common Name

English

Bexarotene [WHO-DD]

Common Name

English

BEXAROTENE [MART.]

Common Name

English

BEXAROTENE [VANDF]

Common Name

English

BEXAROTENE [ORANGE BOOK]

Common Name

English

LGD-1069

Code

English

LGD1069

Code

English

bexarotene [INN]

Common Name

English

P-(1-(5,6,7,8-TETRAHYDRO-3,5,5,8,8-PENTAMETHYL-2-NAPHTHYL)VINYL)BENZOIC ACID

Common Name

English

BEXAROTENE [USAN]

Common Name

English

LG-100069

Code

English

LG100069

Code

English

TARGRETIN

Brand Name

English

4-(1-(5,6,7,8-TETRAHYDRO-3,5,5,8,8-PENTAMETHYL-2-NAPHTHALENYL)ETHENYL)BENZOIC ACID

Systematic Name

English

BEXAROTENE [HSDB]

Common Name

English

BEXAROTENE [MI]

Common Name

English

BEXAROTENE [JAN]

Common Name

English

NSC-747528

Code

English

Classification Tree Code System Code

NDF-RT

N0000007700

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

LIVERTOX

NBK548336

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

WHO-VATC

QL01XX25

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

NDF-RT

N0000007700

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

NDF-RT

N0000175607

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

NDF-RT

N0000007700

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

WHO-ATC

L01XX25

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

NCI_THESAURUS

C804

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

NDF-RT

N0000007700

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

EMA ASSESSMENT REPORTS

TARGRETIN (AUTHORIZED: LYMPHOMA, T-CELL, CUTANEOUS)

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

FDA ORPHAN DRUG

124699

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

NDF-RT

N0000007700

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

Code System Code Type Description

CAS

153559-49-0

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

EPA CompTox

DTXSID1040619

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

NSC

747528

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

MERCK INDEX

m2468

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

Merck Index

SMS_ID

100000089393

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

DRUG BANK

DB00307

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

INN

7782

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

CHEBI

50859

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

USAN

KK-21

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

FDA UNII

A61RXM4375

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

EVMPD

SUB00795MIG

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

IUPHAR

2807

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

NCI_THESAURUS

C1635

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

WIKIPEDIA

BEXAROTENE

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

HSDB

7453

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

DRUG CENTRAL

361

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

MESH

C095105

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

PUBCHEM

82146

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

DAILYMED

A61RXM4375

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

RXCUI

233272

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

RxNorm

ChEMBL

CHEMBL1023

Created by admin on Fri Dec 15 15:34:55 UTC 2023 , Edited by admin on Fri Dec 15 15:34:55 UTC 2023

PRIMARY

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RETINOIC ACID RECEPTOR RXR-GAMMA

TARGET -> AGONIST

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					60VO0DHT4G

RETINOIC ACID RECEPTOR RXR-BETA

TARGET -> AGONIST

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					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

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CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MAJOR

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6-HYDROXY-BEXAROTENE

METABOLITE -> PARENT

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Amount:


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7-HYDROXY-BEXAROTENE

METABOLITE -> PARENT

Qualification:

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Amount:


					915M2UFU28

6-OXO-BEXAROTENE

METABOLITE -> PARENT

Qualification:

PLASMA

Amount:


					POY4N4NX0Q

7-OXO-BEXAROTENE

METABOLITE -> PARENT

Qualification:

PLASMA

Amount:

Related Record Type Details


					A61RXM4375

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Tmax	PHARMACOKINETIC				ORAL ADMINISTRATION

Biological Half-life	PHARMACOKINETIC				ORAL ADMINISTRATION