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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H28FO8P.2Na
Molecular Weight 516.4046
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEXAMETHASONE SODIUM PHOSPHATE

SMILES

[Na+].[Na+].[H][C@@]12C[C@@H](C)[C@](O)(C(=O)COP([O-])([O-])=O)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

InChIKey=PLCQGRYPOISRTQ-FCJDYXGNSA-L
InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1

HIDE SMILES / InChI
Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C22H28FO8P
Molecular Weight 470.4251
Charge -2
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 8 / 8
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:35:21 UTC 2023
Edited
by admin
on Fri Dec 15 15:35:21 UTC 2023
Record UNII
AI9376Y64P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEXAMETHASONE SODIUM PHOSPHATE
EP   GREEN BOOK   JAN   MART.   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
Common Name English
DEXAMETHASONE SODIUM PHOSPHATE [VANDF]
Common Name English
DEXABENE
Brand Name English
MEPHAMESONE
Brand Name English
DEXADRESON
Common Name English
DEXAMETHASONE SODIUM PHOSPHATE [WHO-IP]
Common Name English
MEGACORT
Common Name English
ORADEXON
Brand Name English
TLC-399
Code English
DEXACORT
Brand Name English
DEXAMETHASONE DISODIUM PHOSPHATE
Common Name English
DEXAMETHASONE SODIUM PHOSPHATE [USP IMPURITY]
Common Name English
PRODEX
Brand Name English
9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(dihydrogen phosphate) disodium salt
Common Name English
SOLUDECADRON
Brand Name English
PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11,17-DIHYDROXY-16-METHYL-21-(PHOSPHONOOXY)-, DISODIUM SALT, (11.BETA.,16.ALPHA.)-
Common Name English
TLC399
Code English
AK-DEX
Brand Name English
Dexamethasone sodium phosphate [WHO-DD]
Common Name English
DALALONE
Brand Name English
DEXAMETHASONE SODIUM PHOSPHATE [JAN]
Common Name English
NSC-756722
Code English
DEXAMETHASONE SODIUM PHOSPHATE [GREEN BOOK]
Common Name English
DEXAMETHASONE PHOSPHATE (AS SODIUM)
Common Name English
TOTOCORTIN
Brand Name English
DEXACEN-4
Brand Name English
DEXAMETHASONE 21-PHOSPHATE DISODIUM SALT [MI]
Common Name English
ORGADRONE
Brand Name English
SOLDESAM
Brand Name English
NEODECADRON COMPONENT DEXAMETHASONE SODIUM PHOSPHATE
Common Name English
DEXAIR
Brand Name English
DEXAMETHASONE SODIUM PHOSPHATE [USP MONOGRAPH]
Common Name English
DEXAMETHASONE SODIUM PHOSPHATE COMPONENT OF NEODECADRON
Common Name English
DEXAMETHASONE SODIUM PHOSPHATE [ORANGE BOOK]
Common Name English
DEXAMETHASONE 21-PHOSPHATE DISODIUM SALT
MI  
Common Name English
TURBINAIRE
Common Name English
SOLUPEN N
Brand Name English
DEXAMETHASONI NATRII PHOSPHAS [WHO-IP LATIN]
Common Name English
DEXAMETHASONE SODIUM PHOSPHATE [USP-RS]
Common Name English
DECADRON PHOSPHATE
Brand Name English
DEXAMETHASONE SODIUM PHOSPHATE [MART.]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 373212
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
NCI_THESAURUS C521
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
EU-Orphan Drug EU/3/13/1158
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
Code System Code Type Description
PUBCHEM
16961
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
CHEBI
41879
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
RXCUI
48933
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY RxNorm
CHEBI
4462
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
RS_ITEM_NUM
1177032
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
NSC
756722
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
ECHA (EC/EINECS)
219-243-0
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
SMS_ID
100000090542
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
ChEMBL
CHEMBL1201302
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
NCI_THESAURUS
C1362
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
FDA UNII
AI9376Y64P
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
DRUG BANK
DBSALT000843
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
CAS
2392-39-4
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
MERCK INDEX
m4215
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY Merck Index
EVMPD
SUB01615MIG
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
DAILYMED
AI9376Y64P
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
EVMPD
SUB122698
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
ALTERNATIVE
WHO INTERNATIONAL PHARMACOPEIA
DEXAMETHASONE SODIUM PHOSPHATE
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY Description: A white or almost white, crystalline powder.Solubility: Freely soluble in water; slightly soluble in ethanol (~750 g/L) TS; practically insoluble in dichloromethane R.Category: Adrenal hormone.Storage: Dexamethasone sodium phosphate should be kept in a tightly closed container, protected from light.Additional information: Dexamethasone sodium phosphate is very hygroscopic. Even in the absence of light it is graduallydegraded on exposure to a humid atmosphere, the decomposition being faster at higher temperatures. Dexamethasone sodiumphosphate may exhibit polymorphism.
EPA CompTox
DTXSID3047429
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
MESH
C004180
Created by admin on Fri Dec 15 15:35:22 UTC 2023 , Edited by admin on Fri Dec 15 15:35:22 UTC 2023
PRIMARY
Related Record Type Details
Structure of DEXAMETHASONE PHOSPHATE
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of BETAMETHASONE ACID, (-)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DEXAMETHASONE ETHYL ESTER
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of ALCOHOL
IMPURITY -> PARENT
EP
Structure of ALCOHOL
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (GC)
USP
Structure of 9-FLUORO-11.BETA.,17-DIHYDROXY-16.BETA.-METHYL-3,20-DIOXOPREGN-4-EN-21-YL DIHYDROGEN PHOSPHATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DEXAMETHASONE
IMPURITY -> PARENT
correction factor: for the calculation of content, multiply the peak area of impurity A by 0.75
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of DEXAMETHASONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
Structure of DEXAMETHASONE
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