U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C22H29FO5
Molecular Weight 392.4611
Optical Activity UNSPECIFIED
Defined Stereocenters 8 / 8
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEXAMETHASONE

SMILES

[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

InChIKey=UREBDLICKHMUKA-CXSFZGCWSA-N
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1

HIDE SMILES / InChI

Molecular Formula C22H29FO5
Molecular Weight 392.4611
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 8 / 8
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Fri Dec 15 15:09:21 UTC 2023
Edited
by admin
on Fri Dec 15 15:09:21 UTC 2023
Record UNII
7S5I7G3JQL
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEXAMETHASONE
EMA EPAR   EP   GREEN BOOK   HSDB   INN   MART.   MI   ORANGE BOOK   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
INN  
Official Name English
ISV-305
Code English
DEXASONE
Brand Name English
DEXAMETHASONE [MART.]
Common Name English
DEXAMETHASONE [EP MONOGRAPH]
Common Name English
DEXAMETHASONE COMPONENT OF TOBRADEX ST
Brand Name English
DEXAMETHASONE [ORANGE BOOK]
Common Name English
DEXAMETHASONE COMPONENT OF CIPRODEX
Brand Name English
DEXAMETHASONE [USP-RS]
Common Name English
LOVERINE
Brand Name English
GAMMACORTEN
Common Name English
DEXAMETASONE
Common Name English
Dexamethasone [WHO-DD]
Common Name English
MAXIDEX
Brand Name English
SUPERPREDNOL
Common Name English
DEXAMETHASONE ACETATE IMPURITY A [EP IMPURITY]
Common Name English
FORTECORTIN
Brand Name English
DEXASPORIN COMPONENT DEXAMETHASONE
Brand Name English
BETAMETHASONE IMPURITY A [EP IMPURITY]
Common Name English
DEXAMETHASONE [JAN]
Common Name English
(11.BETA.,16.ALPHA.)-9-FLUORO-11,17,21-TRIHYDROXY-16-METHYLPREGNA-1,4-DIENE-3,20-DIONE
Systematic Name English
DEXA-SINE
Brand Name English
DEXONE
Brand Name English
MAXITROL COMPONENT DEXAMETHASONE
Brand Name English
DEXAMETHASONUM [WHO-IP LATIN]
Common Name English
DEXAMETHASONE COMPONENT OF DEXASPORIN
Brand Name English
NSC-34521
Code English
DEXAMETHASONE [EMA EPAR]
Common Name English
FLUORMETHYLPREDNISOLONE
Common Name English
AEROSEB-DEX
Brand Name English
dexamethasone [INN]
Common Name English
DEXAMETHASONE COMPONENT OF DEXACIDIN
Brand Name English
DEXASITE
Brand Name English
DEXAMONOZON
Brand Name English
DEXAMETHASONE COMPONENT OF TOBRADEX
Brand Name English
DEXAMETHASONE [VANDF]
Common Name English
DEXAPOS
Brand Name English
LUXAZONE
Brand Name English
DECADRON
Brand Name English
DEXYCU
Brand Name English
TOBRADEX ST COMPONENT DEXAMETHASONE
Brand Name English
PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11,17,21-TRIHYDROXY-16-METHYL-,(11.BETA.,16.ALPHA.)-9-FLUORO-11.BETA.,17,21-TRIHYDROXY-16.ALPHA.-METHYLPREGNA-1,4-DIENE-3,20-DIONE
Common Name English
DEXACIDIN COMPONENT DEXAMETHASONE
Brand Name English
DEXAMETHASONE [WHO-IP]
Common Name English
TOBRADEX COMPONENT DEXAMETHASONE
Brand Name English
HEMADY
Brand Name English
HEXADROL
Brand Name English
DECADERM
Brand Name English
DEXAMETHASONE [USP MONOGRAPH]
Common Name English
OZURDEX
Brand Name English
ISOPTO-DEX
Brand Name English
CIPRODEX COMPONENT DEXAMETHASONE
Brand Name English
DEXAMETHASONE [HSDB]
Common Name English
DEXAMETHASONE [MI]
Common Name English
VISUMETAZONE
Common Name English
HEXADECADROL
Common Name English
DEXACORTAL
Brand Name English
9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
Systematic Name English
DECASPRAY
Brand Name English
MILLICORTEN
Common Name English
DEXACORTIN
Brand Name English
DEXAMETHASONE COMPONENT OF MAXITROL
Brand Name English
DEXTENZA
Brand Name English
16.ALPHA.-METHYL-9.ALPHA.-FLUOROPREDNISOLONE
Common Name English
APHTHASOLONE
Common Name English
OTO-104
Code English
DEXAMETHASONE [GREEN BOOK]
Common Name English
Classification Tree Code System Code
WHO-ATC R01AD03
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 8.4
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
CFR 21 CFR 522.540
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
CFR 21 CFR 520.540
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
CFR 21 CFR 520.540A
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QD10AA03
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
FDA ORPHAN DRUG 674718
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC S01BA01
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC S03BA01
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC D07XB05
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QR01AD03
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QD07AB19
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QH02AB02
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 17.2
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
NCI_THESAURUS C521
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
FDA ORPHAN DRUG 795620
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
NDF-RT N0000175576
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QS01CB01
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QD07XB05
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC C05AA09
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
CFR 21 CFR 520.540C
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC R01AD53
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
EMA ASSESSMENT REPORTS OZURDEX (AUTHORIZED: MACULAR EDEMA)
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QS02BA06
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
EMA ASSESSMENT REPORTS ORZUDEX (AUTHORIZED: UVEITIS)
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QD07CB04
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC S03CA01
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC S02BA06
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QS03CA01
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC S01CA01
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
FDA ORPHAN DRUG 626318
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QS01BA01
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
FDA ORPHAN DRUG 115298
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC S02CA06
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QR01AD53
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 8.3
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
LIVERTOX 288
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
CFR 21 CFR 522.542
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
NCI_THESAURUS C267
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QS03BA01
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC D07AB19
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QS01CA01
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QC05AA09
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
NDF-RT N0000175450
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC S01CB01
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
EMA ASSESSMENT REPORTS NEOFORDEX (AUTHORIZED: MULTIPLE MYELOMA)
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC H02AB02
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QA01AC02
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
CFR 21 CFR 520.540B
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC A01AC02
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC D10AA03
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 03
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
EU-Orphan Drug EU/3/10/763
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
CFR 21 CFR 524.1484G
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QH02BX90
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
CFR 21 CFR 520.563
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-ATC D07CB04
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
WHO-VATC QS02CA06
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
Code System Code Type Description
WIKIPEDIA
DEXAMETHASONE
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
NSC
34521
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
PUBCHEM
5743
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
NCI_THESAURUS
C422
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
DAILYMED
7S5I7G3JQL
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
LACTMED
Dexamethasone, Topical
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
HSDB
3053
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
MERCK INDEX
m4215
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY Merck Index
RXCUI
3264
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY RxNorm
DRUG BANK
DB01234
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
CHEBI
32132
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
DEXAMETHASONE
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY Description: Colourless crystals or a white or almost white, crystalline powder; odourless. Solubility: Practically insoluble in water; sparingly soluble in ethanol (~750 g/l) TS.Category: Adrenoglucocorticoid. Storage: Dexamethasone should be kept in a tightly closed container, protected from light.
CHEBI
41879
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
LACTMED
Dexamethasone
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
DRUG CENTRAL
824
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
RS_ITEM_NUM
1176007
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
FDA UNII
7S5I7G3JQL
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
MESH
D003907
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
IUPHAR
2768
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
EPA CompTox
DTXSID3020384
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-003-9
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
EVMPD
SUB07017MIG
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
CAS
50-02-2
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
ChEMBL
CHEMBL384467
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
INN
816
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
SMS_ID
100000092605
Created by admin on Fri Dec 15 15:09:21 UTC 2023 , Edited by admin on Fri Dec 15 15:09:21 UTC 2023
PRIMARY
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METABOLIC ENZYME -> INDUCER
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TARGET -> AGONIST
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TRANSPORTER -> SUBSTRATE
METABOLIC ENZYME -> INDUCER
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METABOLITE -> PARENT
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Related Record Type Details
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
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IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY
correction factor: for the calculation of content, multiply the peak area of impurity A by 0.75
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC