TALMAPIMOD

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C27H30ClFN4O3
Molecular Weight	513.004
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TALMAPIMOD

Structure Search

SMILES

C[C@H]1CN([C@H](C)CN1CC2=CC=C(F)C=C2)C(=O)C3=C(Cl)C=C4N(C)C=C(C(=O)C(=O)N(C)C)C4=C3

InChI

InChIKey=ZMELOYOKMZBMRB-DLBZAZTESA-N

InChI=1S/C27H30ClFN4O3/c1-16-13-33(17(2)12-32(16)14-18-6-8-19(29)9-7-18)26(35)21-10-20-22(25(34)27(36)30(3)4)15-31(5)24(20)11-23(21)28/h6-11,15-17H,12-14H2,1-5H3/t16-,17+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C27H30ClFN4O3
Molecular Weight	513.004
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:03:03 UTC 2023` Edited by `admin` on `Sat Dec 16 18:03:03 UTC 2023`
Record UNII	B1E00KQ6NT
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TALMAPIMOD

Official Name

English

TALMAPIMOD [USAN]

Common Name

English

Talmapimod [WHO-DD]

Common Name

English

talmapimod [INN]

Common Name

English

SCIO 469

Code

English

SCIO-469

Code

English

2-[6-Chloro-5-[[(2R,5S)-4-(4-fluorobenzyl)-2,5-dimethylpiperazin-1-yl]carbonyl]-1-methyl-1H-indol-3-yl]-N,N-dimethyl-2-oxoacetamide

Systematic Name

English

1H-INDOLE-3-ACETAMIDE, 6-CHLORO-5-(((2R,5S)-4-((4-FLUOROPHENYL)METHYL)-2,5-DIMETHYL-1-PIPERAZINYL)CARBONYL)-N,N,1-TRIMETHYL-.ALPHA.-OXO-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2149

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

NCI_THESAURUS

C129825

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

Code System Code Type Description

SMS_ID

100000174942

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

PRIMARY

USAN

SS-75

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

PRIMARY

PUBCHEM

9871074

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

PRIMARY

ChEMBL

CHEMBL514201

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

PRIMARY

CAS

309913-83-5

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

PRIMARY

FDA UNII

B1E00KQ6NT

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

PRIMARY

NCI_THESAURUS

C79841

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

PRIMARY

INN

8957

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

PRIMARY

EPA CompTox

DTXSID10953119

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

PRIMARY

CHEBI

90683

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

PRIMARY

DRUG BANK

DB05412

Created by admin on Sat Dec 16 18:03:03 UTC 2023 , Edited by admin on Sat Dec 16 18:03:03 UTC 2023

PRIMARY

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MITOGEN-ACTIVATED PROTEIN KINASE 11

TARGET -> INHIBITOR


					K6T0L6I32X

TALMAPIMOD HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Related Record Type Details


					B1E00KQ6NT

ACTIVE MOIETY