DORIPENEM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C15H24N4O6S2
Molecular Weight	420.504
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DORIPENEM

Structure Search

SMILES

[H][C@]12[C@@H](C)C(S[C@@H]3CN[C@H](CNS(N)(=O)=O)C3)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O

InChI

InChIKey=AVAACINZEOAHHE-VFZPANTDSA-N

InChI=1S/C15H24N4O6S2/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25)/t6-,7-,8+,9+,10-,11-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C15H24N4O6S2
Molecular Weight	420.504
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:03:18 UTC 2023` Edited by `admin` on `Fri Dec 15 16:03:18 UTC 2023`
Record UNII	BHV525JOBH
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DORIPENEM

Official Name

English

DORIPENEM [EMA EPAR]

Common Name

English

DORIPENEM [MART.]

Common Name

English

doripenem [INN]

Common Name

English

DORIPENEM [USAN]

Common Name

English

1-AZABICYCLO(3.2.0)HEPT-2-ENE-2-CARBOXYLIC ACID, 3-(((3S,5S)-5-(((AMINOSULFONYL)AMINO)METHYL)-3-PYRROLIDINYL)THIO)-6-((1R)-1-HYDROXYETHYL)-4-METHYL-7-OXO-, (4R,5S,6S)-

Common Name

English

(+)-(4R,5S,6S)-6-((1R)-1-HYDROXYETHYL)-4-METHYL-7-OXO-3-(((3S,5S)-5-((SULFAMOYLAMINO)METHYL)-3-PYRROLIDINYL)THIO)-1-AZABICYCLO(3.2.0)HEPT-2-ENE-2-CARBOXYLIC ACID

Systematic Name

English

DORIPENEM [VANDF]

Common Name

English

DORIBAX

Brand Name

English

DORIPENEM [ORANGE BOOK]

Common Name

English

Doripenem [WHO-DD]

Common Name

English

S-4661

Code

English

DORIPENEM [MI]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000011294

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

NDF-RT

N0000175496

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

NCI_THESAURUS

C260

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

EMA ASSESSMENT REPORTS

DORIBAX (WITHDRAW: URINARY TRACT INFECTIONS)

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

FDA ORPHAN DRUG

188104

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

WHO-ATC

J01DH04

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

LIVERTOX

NBK548111

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

WHO-VATC

QJ01DH04

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

Code System Code Type Description

MESH

C099245

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

NCI_THESAURUS

C65470

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

EPA CompTox

DTXSID2046678

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

FDA UNII

BHV525JOBH

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

DRUG CENTRAL

4149

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

DRUG BANK

DB06211

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

MERCK INDEX

m4744

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

Merck Index

USAN

RR-37

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

EVMPD

SUB22196

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

ChEMBL

CHEMBL491571

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

CAS

148016-81-3

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

LACTMED

Doripenem

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

RXCUI

119771

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

RxNorm

PUBCHEM

73303

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

INN

7975

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

SMS_ID

100000089808

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

WIKIPEDIA

DORIPENEM

Created by admin on Fri Dec 15 16:03:18 UTC 2023 , Edited by admin on Fri Dec 15 16:03:18 UTC 2023

PRIMARY

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Amount:


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					H9HCE7993P

BACTEROIDES THETAIOTAOMICRON

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Amount:


					4B035T6NKT

DORIPENEM MONOHYDRATE

SALT/SOLVATE -> PARENT

Amount:


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Comments:

primarily via dehydropeptidase-I

Interaction Type:

MAJOR

Qualification:

PLASMA; URINE

Amount:

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DORIPENEM

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Amount: