OLMUTINIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H26N6O2S
Molecular Weight	486.589
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of OLMUTINIB

Structure Search

SMILES

CN1CCN(CC1)C2=CC=C(NC3=NC(OC4=CC=CC(NC(=O)C=C)=C4)=C5SC=CC5=N3)C=C2

InChI

InChIKey=FDMQDKQUTRLUBU-UHFFFAOYSA-N

InChI=1S/C26H26N6O2S/c1-3-23(33)27-19-5-4-6-21(17-19)34-25-24-22(11-16-35-24)29-26(30-25)28-18-7-9-20(10-8-18)32-14-12-31(2)13-15-32/h3-11,16-17H,1,12-15H2,2H3,(H,27,33)(H,28,29,30)

HIDE SMILES / InChI

Molecular Formula	C26H26N6O2S
Molecular Weight	486.589
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 08:49:59 UTC 2023` Edited by `admin` on `Sat Dec 16 08:49:59 UTC 2023`
Record UNII	CHL9B67L95
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

OLMUTINIB

Official Name

English

OLMUTINIB [USAN]

Common Name

English

N-[3-({2-[4-(4-Methylpiperazin-1-yl)anilino]thieno[3,2-d]pyrimidin-4-yl}oxy)phenyl]prop-2-enamide

Systematic Name

English

BI 1482694

Code

English

BI-1482694

Code

English

olmutinib [INN]

Common Name

English

2-PROPENAMIDE, N-(3-((2-((4-(4-METHYL-1-PIPERAZINYL)PHENYL)AMINO)THIENO(3,2-D)PYRIMIDIN-4-YL)OXY)PHENYL)-

Systematic Name

English

Olmutinib [WHO-DD]

Common Name

English

HM-61713

Code

English

HM61713

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C2167

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

NCI_THESAURUS

C129825

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

WHO-ATC

L01XE40

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

Code System Code Type Description

DRUG CENTRAL

5210

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

EVMPD

SUB182705

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

USAN

DE-87

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

FDA UNII

CHL9B67L95

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

CAS

1353550-13-6

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

WIKIPEDIA

Olmutinib

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

EPA CompTox

DTXSID001319119

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

ChEMBL

CHEMBL3545430

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

NCI_THESAURUS

C101791

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

PUBCHEM

54758501

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

DRUG BANK

DB13164

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

SMS_ID

100000169090

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

INN

10093

Created by admin on Sat Dec 16 08:49:59 UTC 2023 , Edited by admin on Sat Dec 16 08:49:59 UTC 2023

PRIMARY

Related Record Type Details


					XY9T35CX4I

OLMUTINIB HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					9LLR266790

TYROSINE-PROTEIN KINASE JAK3

TARGET -> INHIBITOR


					4VRE4P3LWH

OLMUTINIB DIHYDROCHLORIDE MONOHYDRATE

SALT/SOLVATE -> PARENT


					HG6WHF74KQ

TYROSINE-PROTEIN KINASE BTK C481F MUTANT

TARGET -> INHIBITOR

Interaction Type:

IRREVERSIBLE INHIBITOR

Related Record Type Details


					CHL9B67L95

OLMUTINIB

ACTIVE MOIETY