OLOPATADINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H23NO3
Molecular Weight	337.4122
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of OLOPATADINE

Structure Search

SMILES

CN(C)CC\C=C1\C2=C(COC3=C1C=C(CC(O)=O)C=C3)C=CC=C2

InChI

InChIKey=JBIMVDZLSHOPLA-LSCVHKIXSA-N

InChI=1S/C21H23NO3/c1-22(2)11-5-8-18-17-7-4-3-6-16(17)14-25-20-10-9-15(12-19(18)20)13-21(23)24/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24)/b18-8-

HIDE SMILES / InChI

Molecular Formula	C21H23NO3
Molecular Weight	337.4122
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:50:39 UTC 2023` Edited by `admin` on `Fri Dec 15 15:50:39 UTC 2023`
Record UNII	D27V6190PM
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

OLOPATADINE

Official Name

English

OLOPATADINE [VANDF]

Common Name

English

olopatadine [INN]

Common Name

English

OPATANOL

Brand Name

English

Olopatadine [WHO-DD]

Common Name

English

OLOPATADINE [MI]

Common Name

English

11-((Z)-3-(DIMETHYLAMINO)PROPYLIDENE)-6,11-DIHYDRODIBENZ(B,E)OXEPIN-2-ACETIC ACID

Systematic Name

English

AL-4943A

Code

English

DIBENZ(B,E)OXEPIN-2-ACETIC ACID, 11-(3-(DIMETHYLAMINO)PROPYLIDENE)-6,11-DIHYDRO-, (Z)-

Common Name

English

Classification Tree Code System Code

WHO-ATC

R01AC08

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

NDF-RT

N0000175519

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

WHO-VATC

QS01GX09

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

NCI_THESAURUS

C29578

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

NDF-RT

N0000000190

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

WHO-VATC

QR01AC08

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

WHO-ATC

S01GX09

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

NDF-RT

N0000175628

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

Code System Code Type Description

EVMPD

SUB09431MIG

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

PUBCHEM

5281071

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

WIKIPEDIA

OLOPATADINE

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

MERCK INDEX

m8204

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

Merck Index

DRUG BANK

DB00768

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

IUPHAR

7249

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

EPA CompTox

DTXSID3023390

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

FDA UNII

D27V6190PM

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

ChEMBL

CHEMBL1189432

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

LACTMED

Olopatadine

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

DRUG CENTRAL

1986

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

INN

7257

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

RXCUI

135391

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

RxNorm

CAS

113806-05-6

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

DAILYMED

D27V6190PM

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

SMS_ID

100000085473

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

MESH

C074921

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

NCI_THESAURUS

C61866

Created by admin on Fri Dec 15 15:50:39 UTC 2023 , Edited by admin on Fri Dec 15 15:50:39 UTC 2023

PRIMARY

Related Record Type Details


					28XBT591QG

HISTAMINE H1 RECEPTOR

TARGET -> INHIBITOR


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:

Related Record Type Details


					A4NNX45712

N,N-DIDESMETHYL OLOPATADINE

METABOLITE -> PARENT

Interaction Type:

MINOR

Amount:


					UWI9F1YFCM

OLOPATADINE N-OXIDE

METABOLITE LESS ACTIVE -> PARENT

Comments:

primarily catalyzed by FMO1 and FMO3

Interaction Type:

MINOR

Amount:


					B32K679JBG

N-DESMETHYL OLOPATADINE

METABOLITE ACTIVE -> PARENT

Comments:

N-desmethyl olopatadine (Ml) formation was catalyzed mainly by CYP3A4

Interaction Type:

MAJOR

Amount:


					UWI9F1YFCM

OLOPATADINE N-OXIDE

METABOLITE LESS ACTIVE -> PARENT

Interaction Type:

MINOR

Amount:

Related Record Type Details


					D27V6190PM

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC