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Details

Stereochemistry ACHIRAL
Molecular Formula C27H22Cl2N4
Molecular Weight 473.396
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of CLOFAZIMINE

SMILES

CC(C)\N=C1/C=C2N(C3=CC=C(Cl)C=C3)C4=CC=CC=C4N=C2C=C1NC5=CC=C(Cl)C=C5

InChI

InChIKey=WDQPAMHFFCXSNU-BGABXYSRSA-N
InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3/b30-24+

HIDE SMILES / InChI
Molecular Formula C27H22Cl2N4
Molecular Weight 473.396
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:10:06 UTC 2023
Edited
by admin
on Sat Dec 16 11:10:06 UTC 2023
Record UNII
D959AE5USF
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CLOFAZIMINE
EP   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
INN   USAN  
Official Name English
G-30320
Code English
CLOFAZIMINE [WHO-IP]
Common Name English
CLOFAZIMINE [MI]
Common Name English
CLOFAZIMINE [USP IMPURITY]
Common Name English
CLOFAZIMINE [USP MONOGRAPH]
Common Name English
CLOFAZIMINE [EP MONOGRAPH]
Common Name English
Clofazimine [WHO-DD]
Common Name English
2-PHENAZINAMINE, N,5-BIS(4-CHLOROPHENYL)-3,5-DIHYDRO-3-((1-METHYLETHYL)IMINO)-
Systematic Name English
CLOFAZIMINUM [WHO-IP LATIN]
Common Name English
clofazimine [INN]
Common Name English
CHLOFAZIMINE
Common Name English
CLOFAZIMINE [ORANGE BOOK]
Common Name English
3-(P-CHLOROANILINO)-10-(P-CHLOROPHENYL)-2,10-DIHYDRO-2-(ISOPROPYLIMINO)PHENAZINE
Common Name English
CLOFAZIMINE [USAN]
Common Name English
G 30320
Code English
COLFAZIMINE [VANDF]
Common Name English
CLOFAZIMINE [VANDF]
Common Name English
CLOFAZIMINE [USP-RS]
Common Name English
CLOFAZIMINE [JAN]
Common Name English
NSC-141046
Code English
CLOFAZIMINE [MART.]
Common Name English
LAMPRENE
Brand Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 770820
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
WHO-ATC J04BA01
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
FDA ORPHAN DRUG 2684
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
NCI_THESAURUS C258
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
WHO-VATC QJ04BA01
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
LIVERTOX NBK548658
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
FDA ORPHAN DRUG 646318
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
NDF-RT N0000175483
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
FDA ORPHAN DRUG 338811
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
FDA ORPHAN DRUG 436314
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 6.2.3
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
Code System Code Type Description
RXCUI
2592
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY RxNorm
FDA UNII
D959AE5USF
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
INN
2248
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
CAS
2030-63-9
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
SMS_ID
100000092385
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
NSC
141046
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
DRUG BANK
DB00845
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
RS_ITEM_NUM
1138904
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
EVMPD
SUB06694MIG
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
EPA CompTox
DTXSID7022839
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
CLOFAZIMINE
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY Description: A reddish brown, fine powder; odourless or almost odourless.Solubility: Practically insoluble in water; slightly soluble in ethanol (~750 g/l) TS and in ether R.Category: Antileprosy drug.Storage: Clofazimine should be kept in a well-closed container.Additional information: Clofazimine melts at about 217 ?C.
NCI_THESAURUS
C47456
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
MESH
D002991
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
WIKIPEDIA
CLOFAZIMINE
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
LACTMED
Clofazimine
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
ECHA (EC/EINECS)
217-980-2
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
MERCK INDEX
m3637
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY Merck Index
DRUG CENTRAL
692
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
CHEBI
3749
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
ChEMBL
CHEMBL1292
Created by admin on Sat Dec 16 11:10:07 UTC 2023 , Edited by admin on Sat Dec 16 11:10:07 UTC 2023
PRIMARY
Related Record Type Details
BSEP
TRANSPORTER -> INHIBITOR
MYCOBACTERIUM LEPRAE
TARGET ORGANISM->INHIBITOR
Related Record Type Details
Structure of 1-HYDROXY-CLOFAZIMINE
METABOLITE -> PARENT
Structure of CLOFAZIMINE HYDROGEN-SULFATE
METABOLITE -> PARENT
Structure of PHENOL, 4-((5-(4-CHLOROPHENYL)-3,5-DIHYDRO-3-((1-METHYLETHYL)IMINO)-2-PHENAZINYL)AMINO)-
METABOLITE -> PARENT
Related Record Type Details
Structure of N,5-BIS(4-CHLOROPHENYL)-3,5-DIHYDRO-3-IMINO-2-PHENAZINAMINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 5-(4-CHLOROPHENYL)-3-(ISOPROPYLIMINO)-N-PHENYL-3,5-DIHYDROPHENAZIN-2-AMINE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
Structure of CLOFAZIMINE
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