FEXOFENADINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C32H39NO4
Molecular Weight	501.6564
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FEXOFENADINE

Structure Search

SMILES

CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN2CCC(CC2)C(O)(C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChIKey=RWTNPBWLLIMQHL-UHFFFAOYSA-N

InChI=1S/C32H39NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36)

HIDE SMILES / InChI

Molecular Formula	C32H39NO4
Molecular Weight	501.6564
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:12:51 UTC 2023` Edited by `admin` on `Sat Dec 16 16:12:51 UTC 2023`
Record UNII	E6582LOH6V
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

FEXOFENADINE

Official Name

English

FEXOFENADINE [USP-RS]

Common Name

English

Fexofenadine [WHO-DD]

Common Name

English

FEXOFENADINE [VANDF]

Common Name

English

fexofenadine [INN]

Common Name

English

(±)-P-(1-HYDROXY-4-(4-(HYDROXYDIPHENYLMETHYL)PIPERIDINO)BUTYL)-.ALPHA.-METHYLHYDRATROPIC ACID

Common Name

English

FEXOFENADINE [MI]

Common Name

English

4-(1-HYDROXY-4-(4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINYL)BUTYL)-ALPHA,ALPHA-DIMETHYLBENZENEACETIC ACID

Systematic Name

English

BENZENEACETIC ACID, 4-(1-HYDROXY-4-(4-(HYDROXYDIPHENYLMETHYL)-1-PIPERIDINYL)BUTYL)-.ALPHA.,.ALPHA.-DIMETHYL-, (±)-

Common Name

English

FEXOFENADINE [HSDB]

Common Name

English

TELFAST

Brand Name

English

Classification Tree Code System Code

NDF-RT

N0000000190

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

WHO-ATC

R06AX26

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

NDF-RT

N0000175587

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

WHO-VATC

QR06AX26

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

LIVERTOX

NBK548571

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

NCI_THESAURUS

C29578

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

Code System Code Type Description

DRUG CENTRAL

1170

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

CAS

83799-24-0

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

LACTMED

Fexofenadine

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

MESH

C093230

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

ChEMBL

CHEMBL914

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

HSDB

7486

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

WIKIPEDIA

FEXOFENADINE

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

IUPHAR

4819

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

RXCUI

87636

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

RxNorm

PUBCHEM

3348

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

FDA UNII

E6582LOH6V

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

MERCK INDEX

m5367

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

Merck Index

RS_ITEM_NUM

1270363

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

EVMPD

SUB13883MIG

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

NCI_THESAURUS

C61764

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

EPA CompTox

DTXSID00861411

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

SMS_ID

100000078495

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

CHEBI

5050

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

DRUG BANK

DB00950

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

INN

7469

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

DAILYMED

E6582LOH6V

Created by admin on Sat Dec 16 16:12:53 UTC 2023 , Edited by admin on Sat Dec 16 16:12:53 UTC 2023

PRIMARY

Related Record Type Details


					2S068B75ZU

FEXOFENADINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT


					AIN96D6SGL

OATP1B1

TRANSPORTER -> INHIBITOR


					AIN96D6SGL

OATP1B1

TRANSPORTER -> SUBSTRATE


					E6582LOH6V

EXCRETED UNCHANGED

Qualification:

FECAL

Amount:


					22ES734693

MULTIDRUG RESISTANCE PROTEIN 1

TRANSPORTER -> SUBSTRATE


					E6582LOH6V

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


					G49RZO51ZC

OATP-B

TRANSPORTER -> SUBSTRATE


					570V991KGQ

SOLUTE CARRIER FAMILY 21 MEMBER 3

TRANSPORTER -> SUBSTRATE


					66DDF797LP

OATP-8

TRANSPORTER -> INHIBITOR


					28XBT591QG

HISTAMINE H1 RECEPTOR

TARGET -> INHIBITOR


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Amount:

Related Record Type Details


					7BA5G9Y06Q

PARENT -> METABOLITE ACTIVE

Interaction Type:

MAJOR

Amount:

Related Record Type Details


					E6582LOH6V

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

PROTEIN BINDING	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC

Route of Elimination	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC

Route of Elimination	PHARMACOKINETIC
Tmax	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC