| Stereochemistry | ABSOLUTE |
| Molecular Formula | C20H24F2N4O3 |
| Molecular Weight | 406.4264 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[C@H]1CN(CCN1C2=CC(F)=CC(F)=C2)C(=O)CC[C@]3(NC(=O)NC3=O)C4CC4
InChI
InChIKey=CMLVKUWQFZQPPS-YUNKPMOVSA-N
InChI=1S/C20H24F2N4O3/c1-12-11-25(6-7-26(12)16-9-14(21)8-15(22)10-16)17(27)4-5-20(13-2-3-13)18(28)23-19(29)24-20/h8-10,12-13H,2-7,11H2,1H3,(H2,23,24,28,29)/t12-,20-/m0/s1
| Molecular Formula | C20H24F2N4O3 |
| Molecular Weight | 406.4264 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
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METABOLIC ENZYME -> NON-SUBSTRATE | |||
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METABOLIC ENZYME -> NON-SUBSTRATE | |||
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METABOLIC ENZYME -> INDUCER |
urinary 6β-OH-cortisol/cortisol ratio was increased in five out of 18 subjects (2- to 4.7-fold) |
||
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METABOLIC ENZYME -> SUBSTRATE |
MAJOR
96.7 % (average) metabolized after 60 minutes |
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METABOLIC ENZYME -> SUBSTRATE |
MAJOR
97.3 % (average) metabolized after 60 minutes |
Showing 1 to 5 of 15 entries
