SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA

Approval Year

Substance Class	Protein
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	F660L4205N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA

Common Name

English

SODIUM CHANNEL PROTEIN TYPE V SUBUNIT ALPHA

Common Name

English

NAV1.5

Common Name

English

VOLTAGE-GATED SODIUM CHANNEL SUBUNIT ALPHA NAV1.5

Common Name

English

SCN5A

Common Name

English

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Code System

Code

Type

Description

PHAROS

Q14524

PRIMARY

FDA UNII

F660L4205N

PRIMARY

UNIPROT

Q14524

PRIMARY

WIKIPEDIA

NAV1.5

PRIMARY

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Subunit 0

Glycosylation Type

HUMAN

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Glycosylation Link Type	Site
N	1_214
N	1_283
N	1_288
N	1_291
N	1_318

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Related Record

Type

Details


					459384H98V

ZONISAMIDE

INHIBITOR -> TARGET

Amount:


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CARBAMAZEPINE

INHIBITOR -> TARGET

Amount:


					K94FTS1806

FLECAINIDE

INHIBITOR -> TARGET

Amount:


					6YRL8BWD9H

NEOSAXITOXIN

INHIBITOR RESISTANT -> TARGET

Comments:

NaV1.5, NaV1.8, and NaV1.9 are tetrodotoxin-resistant to varying degrees


					OSP71S83EU

LORLATINIB

NON-INHIBITOR->OFF TARGET

Comments:

failed to inhibit L-type calcium channel, or Nav1.5 sodium current at clinically relevant concentrations.

Amount:

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL	ESTIMATED C10244H15969O2955N2646S111

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