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Details

Stereochemistry ACHIRAL
Molecular Formula C15H12N2O
Molecular Weight 236.2686
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CARBAMAZEPINE

SMILES

NC(=O)N1C2=C(C=CC=C2)C=CC3=C1C=CC=C3

InChI

InChIKey=FFGPTBGBLSHEPO-UHFFFAOYSA-N
InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)

HIDE SMILES / InChI
Molecular Formula C15H12N2O
Molecular Weight 236.2686
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:38:29 UTC 2023
Edited
by admin
on Sat Dec 16 17:38:29 UTC 2023
Record UNII
33CM23913M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CARBAMAZEPINE
EP   HSDB   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RC   USP-RS   VANDF   WHO-DD   WHO-IP  
USAN   INN  
Official Name English
EQUETRO
Brand Name English
TERIL
Brand Name English
NEUROTOP
Common Name English
KARBAMAZEPIN
Common Name English
carbamazepine [INN]
Common Name English
G-32883
Code English
5H-DIBENZ(B,F)AZEPINE-5-CARBOXAMIDE
Systematic Name English
CARBAMAZEPINE [WHO-IP]
Common Name English
TEGRETOL
Brand Name English
NEUROTOL
Common Name English
CARBAMAZEPINE [VANDF]
Common Name English
CARBAMAZEPINE [JAN]
Common Name English
NSC-169864
Code English
SIRTAL
Brand Name English
FINLEPSIN
Brand Name English
CARBAMAZEPINE [ORANGE BOOK]
Common Name English
EPITOL
Brand Name English
CARBAMAZEPINE [EP MONOGRAPH]
Common Name English
STAZEPINE
Brand Name English
Carbamazepine [WHO-DD]
Common Name English
CARBAMAZEPINE [USAN]
Common Name English
CARBAMAZEPINE [MART.]
Common Name English
CARBAMAZEPINE EXTENDED RELEASE
Common Name English
BISTON
Brand Name English
TELESMIN
Brand Name English
CARBAMAZEPINE [USP IMPURITY]
Common Name English
GEIGY 32883
Code English
CARBAMAZEPINE [MI]
Common Name English
CARBATROL
Brand Name English
CARBAMAZEPINE [HSDB]
Common Name English
TIMONIL
Brand Name English
CARBAMAZEPINE ANHYDROUS
Common Name English
OXCARBAZEPINE IMPURITY A [EP IMPURITY]
Common Name English
KARBELEX
Common Name English
TEGRETAL
Brand Name English
CARBAMAZEPINE [USP-RS]
Common Name English
CARBAMAZEPINE [USP MONOGRAPH]
Common Name English
CARBAMAZEPINUM [WHO-IP LATIN]
Common Name English
CARNEXIV
Brand Name English
Classification Tree Code System Code
NCI_THESAURUS C264
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
NDF-RT N0000008486
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
NDF-RT N0000175753
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 24.2.2
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
NDF-RT N0000175751
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
FDA ORPHAN DRUG 43590
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
FDA ORPHAN DRUG 265508
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
WHO-ATC N03AF01
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
LIVERTOX NBK548097
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
WHO-VATC QN03AF01
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
EU-Orphan Drug EU/3/16/1746
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 05
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
Code System Code Type Description
EVMPD
SUB06113MIG
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
LACTMED
Carbamazepine
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
NSC
169864
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
EPA CompTox
DTXSID4022731
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
CAS
298-46-4
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
HSDB
3019
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
ECHA (EC/EINECS)
206-062-7
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
DAILYMED
33CM23913M
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
WIKIPEDIA
CARBAMAZEPINE
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
ChEMBL
CHEMBL108
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
FDA UNII
33CM23913M
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
NDF-RT
N0000191266
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY Cytochrome P450 1A2 Inducers [MoA]
SMS_ID
100000092127
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
PUBCHEM
2554
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
MERCK INDEX
m3053
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY Merck Index
RXCUI
2002
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY RxNorm
DRUG CENTRAL
489
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
DRUG BANK
DB00564
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
INN
1836
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
NCI_THESAURUS
C341
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
NDF-RT
N0000185607
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY Cytochrome P450 2C19 Inducers [MoA]
MESH
D002220
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
WHO INTERNATIONAL PHARMACOPEIA
CARBAMAZEPINE
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY Description: A white to yellowish white, crystalline powder; odourless or almost odourless. Solubility: Practically insoluble in water and ether R; soluble in ethanol (~750 g/l) TS. Category: Antiepileptic drug. Storage: Carbamazepine should be kept in a tightly closed container. Definition: Carbamazepine contains not less than 98.0% and not more than 102.0% of C15H12N2O, calculated with reference to the dried substance.
NDF-RT
N0000187064
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY Cytochrome P450 2B6 Inducers [MoA]
CHEBI
3387
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
NDF-RT
N0000185507
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY Cytochrome P450 2C9 Inducers [MoA]
RS_ITEM_NUM
1093001
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
IUPHAR
5339
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY
NDF-RT
N0000185506
Created by admin on Sat Dec 16 17:38:34 UTC 2023 , Edited by admin on Sat Dec 16 17:38:34 UTC 2023
PRIMARY Cytochrome P450 3A4 Inducers [MoA]
Related Record Type Details
Structure of CARBAMAZEPINE DIHYDRATE
SOLVATE->ANHYDROUS
CYTOCHROME P450 3A4
METABOLIC ENZYME -> SUBSTRATE
CYTOCHROME P450 3A5
METABOLIC ENZYME -> SUBSTRATE
MULTIDRUG RESISTANCE PROTEIN 1
TRANSPORTER -> INDUCER
CYTOCHROME P450 3A5
METABOLIC ENZYME -> INDUCER
SODIUM CHANNEL PROTEIN TYPE 1 SUBUNIT ALPHA
TARGET -> INHIBITOR
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
CYTOCHROME P450 2C8
METABOLIC ENZYME -> SUBSTRATE
CYTOCHROME P450 1A2
METABOLIC ENZYME -> INDUCER
Structure of CARBAMAZEPINE DIHYDRATE
SALT/SOLVATE -> PARENT
SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA
TARGET -> INHIBITOR
CYTOCHROME P450 2C19
METABOLIC ENZYME -> INDUCER
POTENT
Related Record Type Details
Structure of HYDROXYCARBAMAZEPINE, 2-
METABOLITE -> PARENT
Structure of .BETA.-D-GLUCOPYRANOSIDURONIC ACID, 5-(AMINOCARBONYL)-10,11-DIHYDRO-11-HYDROXY-5H-DIBENZ(B,F)AZEPIN-10-YL
METABOLITE -> PARENT
MAJOR
URINE
Structure of .BETA.-D-GLUCOPYRANOSIDURONIC ACID, (10-(AMINOCARBONYL)-9,10-DIHYDRO-9-METHYL-9-ACRIDINYL)METHYL
METABOLITE -> PARENT
MAJOR
URINE
Structure of 2-HYDROXYIMINOSTILBENE
METABOLITE -> PARENT
Structure of 1-DEOXY-1-((5H-DIBENZ(B,F)AZEPIN-5-YLCARBONYL)AMINO)-.BETA.-D-GLUCOPYRANURONIC ACID
METABOLITE -> PARENT
MAJOR
URINE
Structure of 3-HYDROXYCARBAMAZEPINE
METABOLITE -> PARENT
Structure of CARBAMAZEPINE-10,11-EPOXIDE
METABOLITE ACTIVE -> PARENT
Structure of 3H-BENZO(B)OXIRENO(2',3':4,5)BENZO(1,2-F)AZEPINE-3-CARBOXAMIDE
METABOLITE -> PARENT
Structure of 2,3-DIHYDROXYCARBAMAZEPINE
METABOLITE -> PARENT
Structure of 9-ACRIDINECARBOXALDEHYDE
METABOLITE -> PARENT
Structure of DIBENZAZEPINE
METABOLITE -> PARENT
Related Record Type Details
Structure of DIHYDROCARBAMAZEPINE
IMPURITY -> PARENT
Structure of OXCARBAZEPINE
PARENT -> IMPURITY
UNSPECIFIED
EP
Structure of N-ACETYL CARBAMAZEPINE
IMPURITY -> PARENT
Structure of (5H-DIBENZO(B,F)AZEPIN-5-YLCARBONYL)UREA
IMPURITY -> PARENT
Structure of DIBENZAZEPINE
IMPURITY -> PARENT
Structure of IMINODIBENZYL
IMPURITY -> PARENT
Structure of MYTHYLSULFONYLCARBAMAZEPINE
IMPURITY -> PARENT
MINOR
URINE
Structure of 9-METHYLACRIDINE
IMPURITY -> PARENT
Structure of 5-(CHLOROCARBONYL)-5H-DIBENZ(B,F)AZEPINE
IMPURITY -> PARENT
Structure of 10-BROMO-5H-DIBENZO(B,F)AZEPINE-5-CARBOXAMIDE
IMPURITY -> PARENT
Related Record Type Details
Structure of CARBAMAZEPINE
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
NIH
NCATS
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