EGANELISIB

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C30H24N8O2
Molecular Weight	528.564
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@H](NC(=O)C1=C2N=CC=CN2N=C1N)C3=CC4=C(C(=O)N3C5=CC=CC=C5)C(=CC=C4)C#CC6=CN(C)N=C6

InChI

InChIKey=XUMALORDVCFWKV-IBGZPJMESA-N

InChI=1S/C30H24N8O2/c1-19(34-29(39)26-27(31)35-37-15-7-14-32-28(26)37)24-16-22-9-6-8-21(13-12-20-17-33-36(2)18-20)25(22)30(40)38(24)23-10-4-3-5-11-23/h3-11,14-19H,1-2H3,(H2,31,35)(H,34,39)/t19-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C30H24N8O2
Molecular Weight	528.564
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 14:16:58 UTC 2023` Edited by `admin` on `Sat Dec 16 14:16:58 UTC 2023`
Record UNII	FOF5155FMZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

EGANELISIB

Official Name

English

2-amino-N-[(1S)-1-{8-[2-(1-methyl-1H-pyrazol-4-yl)ethynyl]-1-oxo-2-phenyl- 1,2-dihydroisoquinolin-3-yl}ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

Systematic Name

English

eganelisib [INN]

Common Name

English

Eganelisib [WHO-DD]

Common Name

English

PI3K-GAMMA INHIBITOR IPI-549

Common Name

English

IPI-549

Code

English

PYRAZOLO(1,5-A)PYRIMIDINE-3-CARBOXAMIDE, 2-AMINO-N-((1S)-1-(1,2-DIHYDRO-8-(2-(1-METHYL-1H-PYRAZOL-4-YL)ETHYNYL)-1-OXO-2-PHENYL-3-ISOQUINOLINYL)ETHYL)-

Systematic Name

English

(S)-2-AMINO-N-(1-(8-((1-METHYL-1H-PYRAZOL-4-YL)ETHYNYL)-1-OXO-2-PHENYL-1,2- DIHYDROISOQUINOLIN-3-YL)ETHYL)PYRAZOLO(1,5-A)PYRIMIDINE-3-CARBOXAMIDE

Systematic Name

English

EGANELISIB [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129825