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Details

Stereochemistry ACHIRAL
Molecular Formula C35H43N5O4
Molecular Weight 597.747
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of REVEFENACIN

SMILES

CN(CCN1CCC(CC1)OC(=O)NC2=CC=CC=C2C3=CC=CC=C3)C(=O)C4=CC=C(CN5CCC(CC5)C(N)=O)C=C4

InChI

InChIKey=FYDWDCIFZSGNBU-UHFFFAOYSA-N
InChI=1S/C35H43N5O4/c1-38(34(42)29-13-11-26(12-14-29)25-40-19-15-28(16-20-40)33(36)41)23-24-39-21-17-30(18-22-39)44-35(43)37-32-10-6-5-9-31(32)27-7-3-2-4-8-27/h2-14,28,30H,15-25H2,1H3,(H2,36,41)(H,37,43)

HIDE SMILES / InChI
Molecular Formula C35H43N5O4
Molecular Weight 597.747
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 11:11:45 UTC 2023
Edited
by admin
on Sat Dec 16 11:11:45 UTC 2023
Record UNII
G2AE2VE07O
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
REVEFENACIN
INN   USAN   WHO-DD  
INN   USAN  
Official Name English
1-(2-(4-((4-CARBAMOYLPIPERIDIN-1-YL)METHYL)-N-METHYLBENZAMIDO)ETHYL)PIPERIDIN-4-YL N-((1,1'-BIPHENYL)-2-YL)CARBAMATE
Systematic Name English
GSK-1160724
Code English
TD-4208
Code English
GSK1160724
Code English
REVEFENACIN [MI]
Common Name English
YUPELRI
Brand Name English
REVEFENACIN [ORANGE BOOK]
Common Name English
CARBAMIC ACID, N-(1,1'-BIPHENYL)-2-YL-, 1-(2-((4-((4-(AMINOCARBONYL)-1-PIPERIDINYL)METHYL)BENZOYL)METHYLAMINO)ETHYL)-4-PIPERIDINYL ESTER
Systematic Name English
REVEFENACIN [USAN]
Common Name English
Revefenacin [WHO-DD]
Common Name English
revefenacin [INN]
Common Name English
BIPHENYL-2-YLCARBAMIC ACID, 1-(2-((4-(4-CARBAMOYLPIPERIDIN-1-YLMETHYL)BENZOYL)METHYLAMINO)ETHYL)PIPERIDIN-4-YL ESTER
Brand Name English
Classification Tree Code System Code
NCI_THESAURUS C29704
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
Code System Code Type Description
FDA UNII
G2AE2VE07O
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
DRUG BANK
DB11855
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
NCI_THESAURUS
C152200
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
USAN
DE-71
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
MERCK INDEX
m12116
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
RXCUI
2102775
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
EPA CompTox
DTXSID701027775
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
SMS_ID
100000183238
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
CAS
864750-70-9
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
CAS
1211931-83-7
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
NO STRUCTURE GIVEN
INN
10112
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
LACTMED
Revefenacin
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
DAILYMED
G2AE2VE07O
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
PUBCHEM
11753673
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
DRUG CENTRAL
5303
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
WIKIPEDIA
Revefenacin
Created by admin on Sat Dec 16 11:11:46 UTC 2023 , Edited by admin on Sat Dec 16 11:11:46 UTC 2023
PRIMARY
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TRANSPORTER -> SUBSTRATE
MUSCARINIC ACETYLCHOLINE RECEPTOR M5
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TARGET -> INHIBITOR
BINDING
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PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Related Record Type Details
Structure of 1-((4-(2-HYDROXYETHYL(METHYL)CARBAMOYL)PHENYL)METHYL)PIPERIDINE-4-CARBOXAMIDE
METABOLITE -> PARENT
Structure of THRX-195518
METABOLITE ACTIVE -> PARENT
MAJOR
Structure of 1-((4-(2-(4-HYDROXY-1-PIPERIDYL)ETHYL-METHYL-CARBAMOYL)PHENYL)METHYL)PIPERIDINE-4-CARBOXYLIC ACID
METABOLITE -> PARENT
Structure of 1-((4-(2-(4-HYDROXY-1-PIPERIDYL)ETHYLCARBAMOYL)PHENYL)METHYL)PIPERIDINE-4-CARBOXYLIC ACID
METABOLITE -> PARENT
Structure of 1-((4-(2-(4-HYDROXY-1-PIPERIDYL)ETHYL-METHYL-CARBAMOYL)PHENYL)METHYL)PIPERIDINE-4-CARBOXAMIDE
METABOLITE -> PARENT
Structure of 2-((4-((4-CARBAMOYL-1-PIPERIDYL)METHYL)BENZOYL)-METHYL-AMINO)ACETIC ACID
METABOLITE -> PARENT
Related Record Type Details
Structure of REVEFENACIN
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC
Tmax PHARMACOKINETIC
Volume of Distribution PHARMACOKINETIC
NIH
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