TAMSULOSIN

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H28N2O5S
Molecular Weight	408.512
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TAMSULOSIN

Structure Search

SMILES

CCOC1=C(OCCN[C@H](C)CC2=CC(=C(OC)C=C2)S(N)(=O)=O)C=CC=C1

InChI

InChIKey=DRHKJLXJIQTDTD-OAHLLOKOSA-N

InChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C20H28N2O5S
Molecular Weight	408.512
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:11:28 UTC 2023` Edited by `admin` on `Fri Dec 15 16:11:28 UTC 2023`
Record UNII	G3P28OML5I
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TAMSULOSIN

Official Name

English

TAMSULON

Brand Name

English

HIP1402

Code

English

tamsulosin [INN]

Common Name

English

TAMSULOSIN [HSDB]

Common Name

English

HIP-1402

Code

English

Tamsulosine

Common Name

English

TAMSULOSIN [VANDF]

Common Name

English

TAMSULOSIN [MI]

Common Name

English

BENZENESULFONAMIDE, 5-(2-((2-(2-ETHOXYPHENOXY)ETHYL)AMINO)PROPYL)-2-METHOXY-, (R)-

Common Name

English

HGP-0412

Code

English

(-)-(R)-5-(2-((2-(O-ETHOXYPHENOXY)ETHYL)AMINO)PROPYL)-2-METHOXYBENZENESULFONAMIDE

Common Name

English

Tamsulosin [WHO-DD]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QG04CA52

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

WHO-ATC

G04CA52

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

NDF-RT

N0000175553

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

LIVERTOX

NBK548017

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

NCI_THESAURUS

C29713

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

WHO-VATC

QG04CA02

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

NDF-RT

N0000000099

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

WHO-VATC

QG04CA53

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

WHO-ATC

G04CA53

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

WHO-ATC

G04CA02

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

Code System Code Type Description

CAS

106133-20-4

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

WIKIPEDIA

TAMSULOSIN

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

CHEBI

9398

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

RXCUI

77492

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

RxNorm

MERCK INDEX

m10451

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

Merck Index

EPA CompTox

DTXSID3023631

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

DAILYMED

G3P28OML5I

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

DRUG BANK

DB00706

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

DRUG CENTRAL

2562

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

FDA UNII

G3P28OML5I

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

PUBCHEM

129211

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

SMS_ID

100000082422

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

IUPHAR

488

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

INN

6750

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

MESH

C088482

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

EVMPD

SUB10827MIG

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

ChEMBL

CHEMBL836

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

NCI_THESAURUS

C75055

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

HSDB

7744

Created by admin on Fri Dec 15 16:11:28 UTC 2023 , Edited by admin on Fri Dec 15 16:11:28 UTC 2023

PRIMARY

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CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE


					11SV1951MR

TAMSULOSIN HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

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Interaction Type:

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Amount:


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE

Interaction Type:

MAJOR


					P5O3A2DHB2

ALPHA-1D ADRENERGIC RECEPTOR

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Related Record Type Details


					YPH33XH8PL

5-((2R)-2-((2-(2-ETHOXY-5-HYDROXYPHENOXY)ETHYL)AMINO)PROPYL)-2-METHOXYBENZENESULFONAMIDE

METABOLITE -> PARENT

Qualification:

PLASMA

Amount:


					0E45PSU8QW

DEETHYL TAMSULOSIN-O-GLUCURONIDE

METABOLITE -> PARENT

Qualification:

PLASMA; URINE


					GRE0Q7D7FH

DE(ETHOXY)-SULFOOXY TAMSULOSIN

METABOLITE -> PARENT

Qualification:

PLASMA

Amount:


					I0T9MX48ZE

3-(2-(((1R)-2-(3-(AMINOSULFONYL)-4-METHOXYPHENYL)-1-METHYLETHYL)AMINO)ETHOXY)-4-ETHOXYPHENYL .BETA.-D-GLUCOPYRANOSIDURONIC ACID

METABOLITE -> PARENT

Qualification:

URINE

Amount:


					8Y9E3LDI0C

5-((2R)-2-((2-(2-ETHOXY-5-(SULFOOXY)PHENOXY)ETHYL)AMINO)PROPYL)-2-METHOXYBENZENESULFONAMIDE

METABOLITE -> PARENT

Qualification:

URINE

Amount:


					636E91C8QD

DEMETHYL TAMSULOSIN-O-GLUCURONIDE

METABOLITE -> PARENT

Qualification:

URINE

Amount:


					Q2W0EQA69H

4-(2-(((1R)-2-(3-(AMINOSULFONYL)-4-METHOXYPHENYL)-1-METHYLETHYL)AMINO)ETHOXY)-3-ETHOXYPHENYL .BETA.-D-GLUCOPYRANOSIDURONIC ACID

METABOLITE -> PARENT

Qualification:

PLASMA; URINE


					Q6S7J0Y8RB

2-(2-ETHOXYPHENOXY)ACETIC ACID

METABOLITE -> PARENT

Qualification:

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Amount:


					HV9IN7E2ER

5-((2R)-2-((2-(2-ETHOXY-4-HYDROXYPHENOXY)ETHYL)AMINO)PROPYL)-2-METHOXYBENZENESULFONAMIDE

METABOLITE -> PARENT

Qualification:

PLASMA

Amount:


					L3ZWN2HON0

RBX-9001

METABOLITE -> PARENT

Qualification:

URINE

Amount:


					6F9N0FD3GS

DEETHYL TAMSULOSIN

METABOLITE -> PARENT

Qualification:

PLASMA

Amount:

Related Record Type Details


					G3P28OML5I

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Tmax	PHARMACOKINETIC				ORAL ADMINISTRATION

Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC