PHENYLBUTAZONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C19H20N2O2
Molecular Weight	308.3743
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PHENYLBUTAZONE

Structure Search

SMILES

CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3

InChI

InChIKey=VYMDGNCVAMGZFE-UHFFFAOYSA-N

InChI=1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3

HIDE SMILES / InChI

Molecular Formula	C19H20N2O2
Molecular Weight	308.3743
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:16:04 UTC 2023` Edited by `admin` on `Fri Dec 15 15:16:04 UTC 2023`
Record UNII	GN5P7K3T8S
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PHENYLBUTAZONE

Official Name

English

SHIGRODIN

Common Name

English

AMBENE

Brand Name

English

PHEBUZINE

Common Name

English

FLEXAZONE

Common Name

English

BUTAPIRAZOL

Brand Name

English

DIPHENYLBUTAZONE

Common Name

English

3,5-PYRAZOLIDINEDIONE, 4-BUTYL-1,2-DIPHENYL-

Systematic Name

English

ROBIZONE-V

Brand Name

English

3,5-DIOXO-1,2-DIPHENYL-4-N-BUTYLPYRAZOLIDINE

Common Name

English

PHENYLBUTAZONE [MART.]

Common Name

English

EXRHEUDON N

Brand Name

English

FENYLBUTAZON

Common Name

English

PHENYLBUTAZONE [USP-RS]

Common Name

English

BUTACOTE

Brand Name

English

FENIBUTAZONA

Common Name

English

phenylbutazone [INN]

Common Name

English

BUTAZOLIDIN

Brand Name

English

4-Butyl-1,2-diphenyl-3,5-pyrazolidinedione

Systematic Name

English

ARTRIZIN

Brand Name

English

NSC-25134

Code

English

INTRABUTAZONE

Brand Name

English

BUTADIONA

Brand Name

English

ZOLAPHEN

Common Name

English

FENIBUTOL

Brand Name

English

SUXIBUZONE IMPURITY A [EP IMPURITY]

Common Name

English

Phenylbutazone [WHO-DD]

Common Name

English

MEPHA-BUTAZON

Brand Name

English

BUZON

Brand Name

English

PHENYLBUTAZONE [MI]

Common Name

English

PHENYLBUTAZONE [USP MONOGRAPH]

Common Name

English

AZOLID

Systematic Name

English

PHENYZENE

Brand Name

English

INTRAZONE

Brand Name

English

UZONE

Brand Name

English

EQUIPALAZONE

Brand Name

English

BUTATRON

Brand Name

English

PHENYLBUTAZONE [JAN]

Common Name

English

PHENYLBUTAZONE [GREEN BOOK]

Common Name

English

PHENYLBUTAZONE [ORANGE BOOK]

Common Name

English

PHENYLBUTAZONE [VANDF]

Common Name

English

R-3-ZON

Code

English

PHENYLBUTAZONE [IARC]

Common Name

English

DIPHEBUZOL

Common Name

English

PHENYLBUTAZONE [HSDB]

Common Name

English

4-BUTYL-1,2-DIPHENYL-3,5-DIOXOPYRAZOLIDINE

Systematic Name

English

BUTOZ

Brand Name

English

BUTADION

Brand Name

English

BIZOLIN

Brand Name

English

PHENYLBUTAZONE [EP MONOGRAPH]

Common Name

English

ECOBUTAZONE

Brand Name

English

TEVCODYNE

Brand Name

English

G-13871

Code

English

Classification Tree Code System Code

CFR

21 CFR 522.1720

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

CFR

21 CFR 520.1720D

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

CFR

21 CFR 520.1720

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

CFR

21 CFR 520.1720B

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

CFR

21 CFR 520.1720C

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

CFR

21 CFR 520.1720A

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

NCI_THESAURUS

C257

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

WHO-VATC

QM02AA01

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

CFR

21 CFR 520.1720E

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

WHO-VATC

QM01BA01

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

WHO-ATC

M02AA01

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

IARC

Phenylbutazone

WHO-VATC

QM01AA01

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

WHO-ATC

M01BA01

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

WHO-ATC

M01AA01

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

Code System Code Type Description

MERCK INDEX

m8660

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

Merck Index

RS_ITEM_NUM

1531007

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

ChEMBL

CHEMBL101

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

FDA UNII

GN5P7K3T8S

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

WIKIPEDIA

PHENYLBUTAZONE

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

RXCUI

8160

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

RxNorm

NCI_THESAURUS

C66377

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

ECHA (EC/EINECS)

200-029-0

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

EPA CompTox

DTXSID9021136

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

EVMPD

SUB09787MIG

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

CAS

50-33-9

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

PUBCHEM

4781

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

SMS_ID

100000092182

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

IUPHAR

7270

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

HSDB

3159

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

DRUG BANK

DB00812

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

INN

4

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

NSC

25134

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

DAILYMED

GN5P7K3T8S

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

CHEBI

48574

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

DRUG CENTRAL

2145

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

MESH

D010653

Created by admin on Fri Dec 15 15:16:04 UTC 2023 , Edited by admin on Fri Dec 15 15:16:04 UTC 2023

PRIMARY

Related Record Type Details


					005MKH0F6D

SALT/SOLVATE -> PARENT


					5RB28NE79Y

CLOFEZONE ANHYDROUS

SALT/SOLVATE -> PARENT


					0J1026H8UB

PHENYLBUTAZONE PIPERAZINE

SALT/SOLVATE -> PARENT


					TPT3MH65LD

CLOFEZONE

SALT/SOLVATE -> PARENT


					GN5P7K3T8S

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

EP

Amount:


					A09K6UG6UJ

DIETHANOLAMINE PHENYLBUTAZONE

SALT/SOLVATE -> PARENT


					GN5P7K3T8S

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

USP

Amount:


					42EK807V2G

THIAZOLINOBUTAZONE

SALT/SOLVATE -> PARENT

Related Record Type Details


					H806S4B3NS

OXYPHENBUTAZONE

METABOLITE ACTIVE -> PARENT

Comments:

Metabolite to parent drug ratio in non-uraemic human plasma.

Interaction Type:

METABOLITE TO PARENT DRUG RATIO

Qualification:

PLASMA; URINE

Amount:


					H806S4B3NS

OXYPHENBUTAZONE

METABOLITE ACTIVE -> PARENT

Comments:

Oxyphenbutazone, having the same antirheumatic and sodium retaining activities as phenylbutazone, is in clinical use.


					H806S4B3NS

OXYPHENBUTAZONE

METABOLITE ACTIVE -> PARENT

Comments:

Percent of dose excreted in urine as metabolite.

Interaction Type:

AMOUNT ADMINISTERED

Qualification:

URINE

Amount:

Related Record Type Details


					2X02101HVF

BENZIDINE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					F0U1H6UG5C

IMPURITY -> PARENT

Comments:

UNSPECIFIED

Qualification:

EP


					ATD81G944M

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					86TDZ5WP2B

PARENT -> IMPURITY

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					1G3CS09TUK

1,2-DIPHENYLHYDRAZINE

IMPURITY -> PARENT

Comments:

For the calculation of contents, multiply the peak areas by 0.55

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					R4ROQ243U3

4-HYDROXYPHENYLBUTAZONE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					GN5P7K3T8S

ACTIVE MOIETY