CEFTAROLINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H20N8O5S4
Molecular Weight	604.705
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of CEFTAROLINE

Structure Search

SMILES

[H][C@]12SCC(SC3=NC(=CS3)C4=CC=[N+](C)C=C4)=C(N1C(=O)[C@H]2NC(=O)C(=N/OCC)\C5=NSC(N)=N5)C([O-])=O

InChI

InChIKey=RGFBRLNVZCCMSV-BIRGHMBHSA-N

InChI=1S/C22H20N8O5S4/c1-3-35-27-13(16-26-21(23)39-28-16)17(31)25-14-18(32)30-15(20(33)34)12(9-36-19(14)30)38-22-24-11(8-37-22)10-4-6-29(2)7-5-10/h4-8,14,19H,3,9H2,1-2H3,(H3-,23,25,26,28,31,33,34)/b27-13-/t14-,19-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C22H20N8O5S4
Molecular Weight	604.705
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	1
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:30:38 UTC 2023` Edited by `admin` on `Fri Dec 15 16:30:38 UTC 2023`
Record UNII	H36Z0FHR8K
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CEFTAROLINE

Common Name

English

CEFTAROLINE [MI]

Common Name

English

T-91825

Code

English

CEFTAROLINE [VANDF]

Common Name

English

Ceftaroline [WHO-DD]

Common Name

English

PYRIDINIUM, 4-(2-(((6R,7R)-7-(((2Z)-2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-(ETHOXYIMINO)-1-OXOETHYL)AMINO)-2-CARBOXY-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-EN-3-YL)THIO)-4-THIAZOLYL)-1-METHYL-, INNER SALT

Common Name

English

T 91825

Code

English

Classification Tree Code System Code

LIVERTOX

170

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

NDF-RT

N0000175488

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

LIVERTOX

NBK548666

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

LIVERTOX

NBK547862

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

Code System Code Type Description

MERCK INDEX

m3217

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

Merck Index

EVMPD

SUB31649

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

PUBCHEM

9938701

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

EPA CompTox

DTXSID90172341

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

CAS

189345-04-8

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

CHEBI

70729

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

MESH

C490727

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

LACTMED

Ceftaroline

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

RXCUI

1040005

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

RxNorm

DAILYMED

H36Z0FHR8K

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

WIKIPEDIA

Ceftaroline

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

FDA UNII

H36Z0FHR8K

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

SMS_ID

100000124177

Created by admin on Fri Dec 15 16:30:38 UTC 2023 , Edited by admin on Fri Dec 15 16:30:38 UTC 2023

PRIMARY

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					H36Z0FHR8K

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


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METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS

TARGET ORGANISM->INHIBITOR

Amount:


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PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:

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CEFTAROLINE FOSAMIL

PRODRUG -> METABOLITE ACTIVE

Amount:

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					H36Z0FHR8K

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC