DOVITINIB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H21FN6O
Molecular Weight	392.4294
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DOVITINIB

Structure Search

SMILES

CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(N)C5=C(NC4=O)C=CC=C5F

InChI

InChIKey=PIQCTGMSNWUMAF-UHFFFAOYSA-N

InChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11H,7-10H2,1H3,(H,24,25)(H3,23,26,29)

HIDE SMILES / InChI

Molecular Formula	C21H21FN6O
Molecular Weight	392.4294
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:19:07 UTC 2023` Edited by `admin` on `Fri Dec 15 16:19:07 UTC 2023`
Record UNII	I35H55G906
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DOVITINIB

Official Name

English

Dovitinib [WHO-DD]

Common Name

English

TKI-258

Code

English

GFKI-258

Code

English

4-AMINO-5-FLUORO-3-(6-(4-METHYLPIPERAZIN-1-YL)-1H-BENZIMIDAZOL-2-YL)QUINOLIN-2(1H)-ONE

Systematic Name

English

dovitinib [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129825

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

NCI_THESAURUS

C1967

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

FDA ORPHAN DRUG

388012

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

FDA ORPHAN DRUG

210105

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

Code System Code Type Description

EVMPD

SUB177210

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

EPA CompTox

DTXSID901025925

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

PUBCHEM

135398510

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

ChEMBL

CHEMBL522892

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

DRUG BANK

DB05928

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

INN

8847

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

CAS

405169-16-6

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

NCI_THESAURUS

C76199

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

FDA UNII

I35H55G906

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

SMS_ID

100000163084

Created by admin on Fri Dec 15 16:19:07 UTC 2023 , Edited by admin on Fri Dec 15 16:19:07 UTC 2023

PRIMARY

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DOVITINIB

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC