CURCUMIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H20O6
Molecular Weight	368.3799
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure of CURCUMIN

Structure Search

SMILES

COC1=CC(\C=C\C(=O)CC(=O)\C=C\C2=CC(OC)=C(O)C=C2)=CC=C1O

InChI

InChIKey=VFLDPWHFBUODDF-FCXRPNKRSA-N

InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+

HIDE SMILES / InChI

Molecular Formula	C21H20O6
Molecular Weight	368.3799
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	2
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:10:05 UTC 2023` Edited by `admin` on `Fri Dec 15 15:10:05 UTC 2023`
Record UNII	IT942ZTH98
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CURCUMIN

Official Name

English

CURCUMIN [MI]

Common Name

English

CURCUMIN [USP-RS]

Common Name

English

(1E,6E)-1,7-BIS(4-HYDROXY-3-METHOXYPHENYL)-1,6-HEPTADIENE-3,5-DIONE

Systematic Name

English

C.I. NATURAL YELLOW 3

Common Name

English

E-100

Code

English

MERITA EARTH

Common Name

English

C.I. 75300

Common Name

English

E 100

Code

English

TURMERIC YELLOW

Common Name

English

HALDAR

Common Name

English

JIANGHUANGSU

Common Name

English

INS-100(I)

Code

English

Curcumin [WHO-DD]

Common Name

English

CURCUMIN [HSDB]

Common Name

English

CI 75300 [INCI]

Common Name

English

KURKUM

Common Name

English

E100

Code

English

CURCUMIN [INCI]

Common Name

English

NANOCURC

Common Name

English

NSC-687842

Code

English

CI 75300

Official Name

English

LIPOCURC

Common Name

English

KACHA HALDI

Common Name

English

CURCUMIN (CONSTITUENT OF TURMERIC) [DSC]

Common Name

English

INS NO. 100(I)

Code

English

1,7-BIS-(4-HYDROXY-3-METHOXYPHENYL)-HEPTA-1,6-DIENE-3,5-DIONE

Systematic Name

English

CURCUMIN E100

Common Name

English

CURCUMIN [MART.]

Common Name

English

DIFERULOYLMETHANE

Common Name

English

NSC-32982

Code

English

Classification Tree Code System Code

FDA ORPHAN DRUG

167603

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

NCI_THESAURUS

C1323

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

CODEX ALIMENTARIUS (GSFA)

INS-100(I)

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

JECFA EVALUATION

INS-100(I)

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

DSLD

2377 (Number of products:310)

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

NCI_THESAURUS

C1967

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

Code System Code Type Description

WIKIPEDIA

CURCUMIN

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

CAS

458-37-7

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

EU FOOD ADDITIVES

E100(I)

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

MESH

D003474

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

EPA CompTox

DTXSID8031077

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

NCI_THESAURUS

C401

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

DRUG BANK

DB11672

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

GRAS Notification (GRN No.)

822

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

DAILYMED

IT942ZTH98

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

ECHA (EC/EINECS)

207-280-5

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

SMS_ID

100000093154

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

RXCUI

2955

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

RxNorm

GRAS Notification (GRN No.)

686

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

CHEBI

3962

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

EU FOOD ADDITIVES

E 100

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

MERCK INDEX

m3933

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

Merck Index

NSC

687842

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

NSC

32982

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

PUBCHEM

969516

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

FDA UNII

IT942ZTH98

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

RS_ITEM_NUM

1151855

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

EVMPD

SUB29071

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

HSDB

4334

Created by admin on Fri Dec 15 15:10:05 UTC 2023 , Edited by admin on Fri Dec 15 15:10:05 UTC 2023

PRIMARY

Related Record Type Details


					Y49M64GZ4Q

MRP-1

TRANSPORTER -> INHIBITOR

Amount:


					22ES734693

MULTIDRUG RESISTANCE PROTEIN 1

TRANSPORTER -> INHIBITOR


					4AF605U6JN

MRP-2

TRANSPORTER -> INHIBITOR

Related Record Type Details


					BE1PK7RL4M

CURCUMIN GLUCURONIDE

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

PLASMA


					S702I6I4FQ

DEMETHOXYCURCUMIN GLUCURONIDE

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

URINE


					4YU9OA673J

DIHYDROCURCUMIN

METABOLITE -> PARENT

Qualification:

Significant Metabolite


					160DHE331M

CURCUMIN SULFATE

METABOLITE -> PARENT

Interaction Type:

IN-VIVO

Qualification:

PLASMA


					FA26VP94XR

TETRAHYDROCURCUMIN .BETA.-O-GLUCURONIDE

METABOLITE -> PARENT

Qualification:

Significant Metabolite


					7K3QWL7KXP

HEXAHYDROCURCUMIN .BETA.-O-GLUCURONIDE

METABOLITE -> PARENT

Qualification:

Significant Metabolite


					YS2A8X6SX2

OCTAHYDROCURCUMIN

METABOLITE -> PARENT

Interaction Type:

IN-VIVO


					00U0645U03

TETRAHYDRODIFERULOYLMETHANE

METABOLITE -> PARENT

Qualification:

Significant Metabolite


					BE1PK7RL4M

CURCUMIN GLUCURONIDE

METABOLITE -> PARENT

Comments:

Unit: mcg/mL; Fraction of curcumin glucuronide in plasma at Cmax after administration of 10g curcumin (n=6); Total curcumin: 3.10 +/- 0.60 mcg/mL

Interaction Type:

IN-VIVO

Qualification:

PLASMA

Amount:


					RNL5XJ2BA7

HEXAHYDROCURCUMIN

METABOLITE -> PARENT

Interaction Type:

IN-VIVO


					160DHE331M

CURCUMIN SULFATE

METABOLITE -> PARENT

Comments:

Unit: mcg/mL; Fraction of curcumin sulfate in plasma at Cmax after administration of 12 g curcumin; Total curcumin: 2.27 +/- 1.17 mcg/mL

Interaction Type:

IN-VIVO

Qualification:

PLASMA

Amount:

Related Record Type Details


					IT942ZTH98

CURCUMIN

ACTIVE MOIETY