U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C21H23ClFNO2
Molecular Weight 375.864
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HALOPERIDOL

SMILES

OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C3=CC=C(Cl)C=C3

InChI

InChIKey=LNEPOXFFQSENCJ-UHFFFAOYSA-N
InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2

HIDE SMILES / InChI
Molecular Formula C21H23ClFNO2
Molecular Weight 375.864
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:28:50 UTC 2023
Edited
by admin
on Fri Dec 15 16:28:50 UTC 2023
Record UNII
J6292F8L3D
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HALOPERIDOL
EP   HSDB   INN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD   WHO-IP  
INN   USAN  
Official Name English
HALOPERIDOL COMPONENT OF VESALIUM
Brand Name English
EUKYSTOL
Common Name English
HALOPERIDOL DECANOATE IMPURITY G [EP IMPURITY]
Common Name English
VESALIUM COMPONENT HALOPERIDOL
Brand Name English
HALOPERIDOL [HSDB]
Common Name English
HALOPERIDOL [WHO-IP]
Common Name English
SIGAPERIDOL
Common Name English
HALDOL
Brand Name English
KESELAN
Common Name English
ALOPERIDIN
Common Name English
NSC-170973
Code English
Haloperidol [WHO-DD]
Common Name English
HALOPERIDOL [EP MONOGRAPH]
Common Name English
HALOPERIDOL [JAN]
Common Name English
R-1625
Code English
NSC-615296
Code English
HALOPERIDOLUM [WHO-IP LATIN]
Common Name English
SERENELFI
Common Name English
SERENASE
Common Name English
BIOPERIDOLO
Common Name English
1-BUTANONE, 4-(4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL)-1-(4-FLUOROPHENYL)-
Systematic Name English
HALOPERIDOL [MI]
Common Name English
SERENACE
Common Name English
HALOPERIDOL [USP MONOGRAPH]
Common Name English
HALOPERIDOL DECANOATE IMPURITY, HALOPERIDOL- [USP IMPURITY]
Common Name English
HALOPERIDOL [MART.]
Common Name English
NEURODOL
Common Name English
LINTON
Common Name English
HALOPERIDOL [ORANGE BOOK]
Common Name English
HALOPERIDOL [USP IMPURITY]
Common Name English
HALOPERIDOL [USAN]
Common Name English
haloperidol [INN]
Common Name English
HALOPERIDOL [VANDF]
Common Name English
DOZIC
Common Name English
HALOPERIDOL [USP-RS]
Common Name English
Classification Tree Code System Code
LIVERTOX NBK548393
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
NDF-RT N0000180182
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
WHO-ATC N05AD01
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
WHO-ESSENTIAL MEDICINES LIST 24.1
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
WHO-VATC QN05AD01
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
NCI_THESAURUS C323
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
NCI_THESAURUS C66883
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
Code System Code Type Description
WHO INTERNATIONAL PHARMACOPEIA
HALOPERIDOL
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY Description: A white to faintly yellowish, amorphous or microcrystalline powder; odourless. Solubility: Practically insoluble in water; soluble in 50 parts of ethanol (~750 g/l) TS and in 200 parts of ether R. Category: Neuroleptic. Storage: Haloperidol should be kept in a well-closed container, protected from light. Definition: Haloperidol contains not less than 98.0% and not more than 101.0% of C21H23ClFNO2, calculated with reference to the dried substance.
IUPHAR
86
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
RS_ITEM_NUM
1303002
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
CHEBI
5613
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
DRUG BANK
DB00502
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
DAILYMED
J6292F8L3D
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
HSDB
3093
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
LACTMED
Haloperidol
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
WIKIPEDIA
HALOPERIDOL
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
FDA UNII
J6292F8L3D
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
RXCUI
5093
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY RxNorm
CAS
52-86-8
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
PUBCHEM
3559
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
ChEMBL
CHEMBL54
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
MESH
D006220
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-155-6
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
MERCK INDEX
m5904
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY Merck Index
NSC
615296
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
NCI_THESAURUS
C537
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
EPA CompTox
DTXSID4034150
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
SMS_ID
100000092645
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
EVMPD
SUB08005MIG
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
INN
918
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
NSC
170973
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
DRUG CENTRAL
1353
Created by admin on Fri Dec 15 16:28:50 UTC 2023 , Edited by admin on Fri Dec 15 16:28:50 UTC 2023
PRIMARY
Related Record Type Details
D(2) DOPAMINE RECEPTOR
TARGET->INVERSE AGONIST
Ki
Structure of HALOPERIDOL HYDROCHLORIDE
SALT/SOLVATE -> PARENT
Structure of HALOPERIDOL
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
USP
D(2) DOPAMINE RECEPTOR
TARGET -> AGONIST
BINDING
IC50
CYTOCHROME P450 2D6
METABOLIC ENZYME -> SUBSTRATE
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Structure of HALOPERIDOL
BASIS OF STRENGTH->SUBSTANCE
ASSAY (TITRATION)
EP
Related Record Type Details
Structure of HALOPERIDOL PYRIDINIUM
METABOLITE TOXIC -> PARENT
Structure of 4-(4-(P-CHLOROPHENYL)-2,5,6-TRIHYDROPYRIDINO)-4'-FLUOROBUTYROPHENONE
METABOLITE -> PARENT
Structure of DIHYDROHALOPERIDOL, (S)-
METABOLITE -> PARENT
Structure of 3-(4-FLUOROBENZOYL)PROPANOIC ACID
METABOLITE -> PARENT
Structure of HALOPERIDOL GLUCURONIDE
PARENT -> METABOLITE
Structure of 4-(4-CHLOROPHENYL)-4-PIPERIDINOL
METABOLITE INACTIVE -> PARENT
Structure of HALOPERIDOL DECANOATE
PRODRUG -> METABOLITE ACTIVE
Related Record Type Details
Structure of 4-(4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDIN-1-YL)-1-(2-FLUOROPHENYL)BUTAN-1-ONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of HALOPERIDOL DECANOATE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 4-(4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDIN-1-YL)-1-(4-(4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDIN-1-YL)PHENYL)BUTAN-1-ONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 4-(4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDIN-1-YL)-1-(4-(4-(4-CHLOROPHENYL)-4-HYDROXYPIPERIDIN-1-YL)PHENYL)BUTAN-1-ONE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
Structure of HALOPERIDOL
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966