ILOPROST

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	EPIMERIC
Molecular Formula	C22H32O4
Molecular Weight	360.4871
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 6
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure of ILOPROST

Structure Search

SMILES

[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)C(C)CC#CC)[C@@]1([H])C\C(C2)=C\CCCC(O)=O

InChI

InChIKey=HIFJCPQKFCZDDL-ACWOEMLNSA-N

InChI=1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8+/t15?,17-,18+,19-,20+,21+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C22H32O4
Molecular Weight	360.4871
Charge	0
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	5 / 6
E/Z Centers	2
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 01:38:50 UTC 2023` Edited by `admin` on `Sat Dec 16 01:38:50 UTC 2023`
Record UNII	JED5K35YGL
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ILOPROST

Official Name

English

PENTANOIC ACID, 5-((3AS,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-((1E,3S)-3-HYDROXY-4-METHYL-1-OCTEN-6-YNYL)-2(1H)-PENTALENYLIDENE)-, (5E)-

Common Name

English

ILOPROST [JAN]

Common Name

English

ILOPROST [MART.]

Common Name

English

iloprost [INN]

Common Name

English

ILOPROST [VANDF]

Common Name

English

(5E)-[3aS,4R,5R,6aS)-5-Hydroxy-4-[(1E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]-hexahydropentalen-2(1H)-ylidene]pentanoic acid

Common Name

English

Iloprost [WHO-DD]

Common Name

English

ZK-00036374

Code

English

ILOPROST [MI]

Common Name

English

VENTAVIS

Brand Name

English

ILOPROST [EMA EPAR]

Common Name

English

ENDOPROST

Brand Name

English

ILOPROST [ORANGE BOOK]

Common Name

English

ZK-36374

Code

English

ILOPROST [USAN]

Common Name

English

ILOMEDIN

Brand Name

English

CILOPROST

Brand Name

English

ZK 00036374

Code

English

Classification Tree Code System Code

NDF-RT

N0000011280

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

FDA ORPHAN DRUG

655118

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

WHO-ATC

B01AC11

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

EMA ASSESSMENT REPORTS

VENTSVIS (AUTHORIZED: HYPERTENSION, PULMONARY)

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

NDF-RT

N0000011280

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

WHO-VATC

QB01AC11

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

FDA ORPHAN DRUG

186904

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

FDA ORPHAN DRUG

364012

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

LIVERTOX

499

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

NCI_THESAURUS

C1892

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

NDF-RT

N0000011280

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

NCI_THESAURUS

C78568

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

FDA ORPHAN DRUG

38789

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

EU-Orphan Drug

EU/3/00/014

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

FDA ORPHAN DRUG

886722

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

FDA ORPHAN DRUG

40089

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

NDF-RT

N0000175603

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

FDA ORPHAN DRUG

324610

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

Code System Code Type Description

FDA UNII

JED5K35YGL

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

EVMPD

SUB08136MIG

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

DRUG CENTRAL

1422

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

DAILYMED

JED5K35YGL

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

INN

4972

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

WIKIPEDIA

ILOPROST

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

SMS_ID

100000085458

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

CAS

78919-13-8

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

NCI_THESAURUS

C48397

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

DRUG BANK

DB01088

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

PUBCHEM

5311181

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

USAN

QQ-106

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

IUPHAR

1895

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

EPA CompTox

DTXSID2041046

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

MERCK INDEX

m6212

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

Merck Index

RXCUI

40138

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

RxNorm

MESH

D016285

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

CHEBI

63916

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

ChEMBL

CHEMBL494

Created by admin on Sat Dec 16 01:38:50 UTC 2023 , Edited by admin on Sat Dec 16 01:38:50 UTC 2023

PRIMARY

Related Record Type Details


					45U5P0UB24

ILOPROST S-ISOMER

ACTIVE ISOMER -> PARENT

Amount:


					807T91913V

ILOPROST TROMETHAMINE

SALT/SOLVATE -> PARENT

Amount:


					D381C4K8ZW

PROSTAGLANDIN E2 RECEPTOR EP1 SUBTYPE

TARGET -> AGONIST

Qualification:

Ki

Amount:


					66UL4XJJ3X

PROSTACYCLIN RECEPTOR

TARGET -> AGONIST

Qualification:

Ki

Amount:


					6EM0N6I9ZP

PROSTAGLANDIN E2 RECEPTOR EP4 SUBTYPE

TARGET->WEAK AGONIST

Qualification:

Ki

Amount:


					66UL4XJJ3X

PROSTACYCLIN RECEPTOR

TARGET -> AGONIST

Amount:


					AHG2128QW6

ILOPROST R-ISOMER

LESS ACTIVE ISOMER -> PARENT

Amount:


					7L8YW0VG16

PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE

TARGET -> AGONIST

Qualification:

Ki

Amount:

Related Record Type Details


					JED5K35YGL

ILOPROST

ACTIVE MOIETY

Amount: