ALOGLIPTIN

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H21N5O2
Molecular Weight	339.3916
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ALOGLIPTIN

Structure Search

SMILES

CN1C(=O)C=C(N2CCC[C@@H](N)C2)N(CC3=C(C=CC=C3)C#N)C1=O

InChI

InChIKey=ZSBOMTDTBDDKMP-OAHLLOKOSA-N

InChI=1S/C18H21N5O2/c1-21-17(24)9-16(22-8-4-7-15(20)12-22)23(18(21)25)11-14-6-3-2-5-13(14)10-19/h2-3,5-6,9,15H,4,7-8,11-12,20H2,1H3/t15-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C18H21N5O2
Molecular Weight	339.3916
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:57:30 UTC 2023` Edited by `admin` on `Sat Dec 16 17:57:30 UTC 2023`
Record UNII	JHC049LO86
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ALOGLIPTIN

Official Name

English

ALOGLIPTIN [MI]

Common Name

English

Alogliptin [WHO-DD]

Common Name

English

ALOGLIPTIN [VANDF]

Common Name

English

alogliptin [INN]

Common Name

English

Classification Tree Code System Code

WHO-ATC

A10BH04

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

NCI_THESAURUS

C98086

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

WHO-ATC

A10BD09

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

WHO-VATC

QA10BD13

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

WHO-ATC

A10BD13

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

WHO-VATC

QA10BD09

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

WHO-VATC

QA10BH04

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

NDF-RT

N0000175913

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

Code System Code Type Description

LACTMED

Alogliptin

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

INN

8814

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

RXCUI

1368001

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

RxNorm

HSDB

8203

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

CHEBI

72323

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

FDA UNII

JHC049LO86

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

WIKIPEDIA

ALOGLIPTIN

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

EPA CompTox

DTXSID90234130

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

DRUG BANK

DB06203

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

NCI_THESAURUS

C76906

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

MESH

C520853

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

CAS

850649-61-5

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

ChEMBL

CHEMBL376359

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

PUBCHEM

11450633

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

EVMPD

SUB32564

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

IUPHAR

6319

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

MERCK INDEX

m1572

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

Merck Index

DAILYMED

JHC049LO86

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

SMS_ID

100000124299

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

DRUG CENTRAL

4340

Created by admin on Sat Dec 16 17:57:31 UTC 2023 , Edited by admin on Sat Dec 16 17:57:31 UTC 2023

PRIMARY

Related Record Type Details


					EEN99869SC

ALOGLIPTIN BENZOATE

SALT/SOLVATE -> PARENT


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE


					JHC049LO86

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


					RIGEZF4K05

DIPEPTIDYL PEPTIDASE 4 MEMBRANE FORM

TARGET -> INHIBITOR

Qualification:

IC50

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:

Related Record Type Details


					625UXD6CJI

2-((6-((3R)-3-AMINO-1-PIPERIDINYL)-3,4-DIHYDRO-2,4-DIOXO-1(2H)-PYRIMIDINYL)METHYL)BENZONITRILE

METABOLITE ACTIVE -> PARENT

Interaction Type:

MINOR

Amount:


					U93RK9Q9H6

N-ACETYL ALOGLIPTIN

METABOLITE INACTIVE -> PARENT

Interaction Type:

MINOR

Related Record Type Details


					JHC049LO86

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC				SINGLE DOSE INTRAVENOUS ADMINISTRATION

Tmax	PHARMACOKINETIC				SINGLE DOSE ORAL ADMINISTRATION

Biological Half-life	PHARMACOKINETIC