MILRINONE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H9N3O
Molecular Weight	211.2194
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MILRINONE

Structure Search

SMILES

CC1=C(C=C(C#N)C(=O)N1)C2=CC=NC=C2

InChI

InChIKey=PZRHRDRVRGEVNW-UHFFFAOYSA-N

InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)

HIDE SMILES / InChI

Molecular Formula	C12H9N3O
Molecular Weight	211.2194
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:11:59 UTC 2023` Edited by `admin` on `Fri Dec 15 16:11:59 UTC 2023`
Record UNII	JU9YAX04C7
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

MILRINONE

Official Name

English

Milrinone [WHO-DD]

Common Name

English

MILRILA

Brand Name

English

MILRINONE [USP-RS]

Common Name

English

WIN 47,203-2

Code

English

MILRINONE [USAN]

Common Name

English

MILRINONE [JAN]

Common Name

English

WIN-47203-2

Code

English

MILRINONE [USP MONOGRAPH]

Common Name

English

MILRINONE [MI]

Common Name

English

milrinone [INN]

Common Name

English

MILRINONE [VANDF]

Common Name

English

NSC-760072

Code

English

MILRINONE [MART.]

Common Name

English

(3,4'-BIPYRIDINE)-5-CARBONITRILE, 1,6-DIHYDRO-2-METHYL-6-OXO-

Systematic Name

English

1,6-DIHYDRO-2-METHYL-6-OXO(3,4'-BIPYRIDINE)-5-CARBONITRILE

Systematic Name

English

Classification Tree Code System Code

NDF-RT

N0000175598

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

FDA ORPHAN DRUG

565916

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

WHO-ATC

C01CE02

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

NDF-RT

N0000175086

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

WHO-VATC

QC01CE02

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

NCI_THESAURUS

C744

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

Code System Code Type Description

MESH

D020105

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

ECHA (EC/EINECS)

278-903-6

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

SMS_ID

100000080655

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

EPA CompTox

DTXSID5023324

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

NCI_THESAURUS

C61848

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

RS_ITEM_NUM

1443908

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

ChEMBL

CHEMBL189

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

USAN

T-72

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

WIKIPEDIA

MILRINONE

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

INN

5383

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

DAILYMED

JU9YAX04C7

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

CAS

78415-72-2

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

MERCK INDEX

m7548

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

Merck Index

DRUG CENTRAL

1809

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

CHEBI

50693

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

RXCUI

52769

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

RxNorm

NSC

760072

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

DRUG BANK

DB00235

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

EVMPD

SUB08968MIG

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

IUPHAR

5225

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

FDA UNII

JU9YAX04C7

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

PUBCHEM

4197

Created by admin on Fri Dec 15 16:11:59 UTC 2023 , Edited by admin on Fri Dec 15 16:11:59 UTC 2023

PRIMARY

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					JOC85XIO65

CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE A

TARGET -> INHIBITOR

Qualification:

IC50

Amount:

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					6G5D63NZ32

MILRINONE O-GLUCURONIDE

METABOLITE -> PARENT

Interaction Type:

MAJOR

Qualification:

URINE

Amount:

Related Record Type Details


					75E39HK2X2

1,6-DIHYDRO-2-METHYL-6-OXO(3,4'-BIPYRIDINE)-5-CARBOXAMIDE

IMPURITY -> PARENT

Amount:

Related Record Type Details


					JU9YAX04C7

MILRINONE

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC		`JU9YAX04C7` MILRINONE

Biological Half-life	PHARMACOKINETIC		`JU9YAX04C7` MILRINONE		Normal renal function PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC		`JU9YAX04C7` MILRINONE		Severe heart failure with (CVVH)continuous venovenous hemfiltration. PHARMACOKINETIC